Lead Scientist, Cell-Free

LanzaTech | Industry | Skokie, IL | More →

Company Overview

Mission-driven LanzaTech is a revolutionary solution to climate change, capturing pollution to clean our skies and oceans and create new high value products for a sustainable future. LanzaTech captures pollution to make fuels and chemicals, including sustainable jet fuel and products you use every day. The technology is like retrofitting a brewery onto an emission source like a steel mill or a landfill site, but instead of using sugars and yeast to make beer, pollution is converted by biology to fuels and chemicals! Imagine a day when your plane is powered by recycled emissions, when your yoga pants started life as pollution from a steel mill. This future is possible using LanzaTech technology.

  • 2021 Biofuels Digest #1 Hottest Company in Renewable Fuels, Chemicals & Biomaterials
  • 2020 Biofuels Digest #3 Best Company to work for in the Advanced Bioeconomy
  • 2020 Fast Company World Changing Company
  • 2020 CNBC #43 on Top 50 Disrupter Companies list
  • 2019 Chicago Innovation Awards Winner
  • 2019 Fortune Magazine – Change the World – Companies to watch
  • 2019 Kirkpatrick Chemical Engineering Achievement Award

LanzaTech is committed to Diversity, Equity & Inclusion as part of our mission, culture & core values
This position is open to candidates authorized to work in the United States on a full-time basis for any employer. LanzaTech is an Equal Employment Opportunity employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, gender, sexual orientation, gender identity or expression, national origin, age, genetic information, disability, or veteran status.

About the Role

LanzaTech is looking for a motivated, high energy, well-organized, collaborative Scientist to lead research and development of cell-free technologies at LanzaTech. The role will include:

Work on a cross-functional team to support projects that require and/or would benefit from cell-free applications and experiments
Leading the development, optimization, and automation of cell-free protein synthesis workflows both in model systems and gas-fermenting organisms
Evaluating and leading testing of additional cell-free applications such as biosensors and manufacturing
Conducting work collaboratively across multiple teams at LanzaTech including Automation, Fermentation, Analytics, and Engineering


Follow all safety requirements for working in the offices and laboratories, including completing any required trainings
Maintain a clean and functional laboratory space
Assist in upkeep of laboratory reagents and stock supplies to run experiments
Maintain an up-to-date laboratory notebook tracking experiments, data, and interpretation of results
Perform cell-free experiments and workflows in support of externally funded projects
Lead the development of new cell-free workflows and capabilities at LanzaTech
Establish and write standard operating procedures (SOPs) for laboratory workflows
Stay up-to-date with advancements in cell-free scientific field
Attend and participate in Enzymology and Synthetic Biology group meetings as well as relevant project updates with partners
Present findings and developments both internally to LanzaTech teams and externally to partners
Instruct and advise LanzaTech colleagues on established workflows
Guide and train junior scientists such as research associates, technicians, and interns
Develop research plans and preliminary data in support of grant proposals
Use of laboratory management systems, in-house experimental design tools, and computational tools to improve efficiency in design, execution, and interpretation of experiments



Ph.D. in Biochemistry, Synthetic Biology, Bioengineering, Molecular Biology, Chemical Engineering, or a related field OR M.Sc. in related field with 2+ years relevant laboratory experience with cell-free applications post-graduation
Demonstrated experience with designing, executing, and reporting cell-free experiments
Knowledgeable with the current cell-free protein synthesis/cell-free applications field
Strong organizational, time management, and interpersonal skills
Experience writing reports and/or manuscripts centered on cell-free applications (e.g., transcription, translation, sensing and screening)
Experience giving group presentations
High attention to detail and careful record keeping
Independent and highly self-motivated
Excellent communication skills and a desire to work in a team
Ability to conduct research independently and manage multiple tasks in parallel
Awareness of safety issues in the work environment
Strong computer literacy including Microsoft Office, SharePoint or equivalent applications

Highly Preferred

Experience and/or working knowledge of anaerobic microbes
Experience with multiple cell-free protein synthesis systems (e.g., E. coli and Wheat Germ)
Experience with multiple protein reporter, detection, and/or quantification approaches (e.g., luciferase, radiolabeling, and blotting)
Experience with multiple DNA cloning methods (e.g., Gibson and Golden Gate assemblies)


LanzaTech Headquarters
Skokie, IL USA

Apply HERE