Postdoctoral Scholar in Gene Synthesis Technologies

University of Oregon | Academic | Eugene, OR | More →

The Plesa lab ( has a funded position for a postdoctoral scholar to work on gene synthesis technologies. Our lab aims to accelerate the pace at which we understand and engineer biological systems, particularly proteins. We are interested in uncovering the rules for the engineering of novel protein function, particularly in the areas of sensing and interfacing with engineering. Towards this end, we develop new technologies for gene synthesis, multiplex functional assays, in-vivo mutagenesis, and genotype-phenotype linkages. These allow us to both access the huge sequence diversity present in natural systems as well as carry out testing of rationally designed hypotheses encoded onto DNA at much larger scales than previously possible. Using these approaches, we aim to quickly characterize and engineer entire protein families, rather than focusing on individual proteins. Our work is highly-interdisciplinary and touches on aspects from many fields including bioengineering, protein engineering, biochemistry, synthetic biology, molecular biology, microbiology, structural biology, genetics, bioinformatics, and quantitative biology.

The postdoc will be responsible for conducting research and technical activities related to sponsored projects in the lab. Research work will include designing and optimizing new scalable gene synthesis methods to enable longer genes, higher yields, and lower cost. Essential responsibilities will include designing and conducting experiments, interpreting data, writing manuscripts, writing research proposals, assembling and delivering research presentations locally and nationally, assisting and training other researchers in the laboratory, and maintaining laboratory equipment.

This position will work closely with other lab researchers (students, postdocs, and technicians) and with Dr. Plesa. The position will be given a level of independence depending on the level of experience, with the goal of becoming a fully independent researcher by the end of their term as guided by a formal mentoring plan.

Further position details available in the job posting link above. Those interested are encouraged to contact Calin Plesa ([email protected]) by email with a PDF copy of their CV and a cover letter outlining their research interests.