Synthetic Biology Scientist

ResVita Bio | Industry | Berkeley, CA | More →

ResVita Bio is an early-stage synthetic biology start-up spun out of UC Berkeley. We seek to build genetically engineered skin probiotics to treat chronic skin diseases. We have developed a platform for controlled colonization of the skin with engineered therapeutic bacteria and are applying this to multiple disease areas. We have submitted an application to the FDA for the Rare Pediatric Disease Designation for Netherton Syndrome, a devastating skin condition that most severely affects children, and are actively progressing programs in atopic dermatitis and psoriasis.

ResVita Bio is hiring a scientist who is eager to push the boundaries of synthetic biology and metabolic engineering to develop the next generation of bio-therapies to treat deadly and destructive skin diseases. This is an exciting, multi-disciplinary position branching the fields of immunology, dermatology, synthetic biology and metabolic engineering. The scientist will work closely with our CEO to advance our platform to develop and test therapeutic strains for the treatment of skin diseases. The ideal candidate will have experience in murine models, but prior experience with microbial communities is not required.

As a small start-up, your creativity, values, and managerial skills will help shape ResVita Bio’s path as well as its culture. At ResVita Bio, we believe a diverse workforce will help us achieve our mission to meaningfully change the outcome of many human diseases. Come and play an important role in the development and commercialization of a technology at the forefront of biology and engineering.

Responsibilities
Design and construct DNA expression and integration cassettes, building and screening combinatorial strain/enzyme libraries, and analyze and improve of strain performance
Develop new genetic tools and improve media engineering to improve in vivo strain performance
Directly test designed strains in skin-damaged murine models
Collaborate with immunologists to design and interpret animal experiments
Contribute to the generation and documentation of intellectual property

Key Qualifications
PhD in bioengineering, chemical engineering, molecular biology, or biochemistry or a related discipline
Proficient with microbial genetic engineering and molecular biology bench work
Direct experience in synthetic biology or metabolic engineering projects
Ideally, the candidate has some experience with murine models
Must be able to work independently and have strong organizational and planning skills
Eagerness to work collaboratively on a team of experts while adapting to the fast-paced needs of an early-stage startup