Individual Members

John Glass

Dr. John Glass is a Professor and leader of the J. Craig Venter Institute (JCVI) Synthetic Biology and Bioenergy Group. His expertise is in molecular biology, microbial pathogenesis, RNA virology, and microbial genomics. Glass is part of the Venter Institute team that created the first bacterial cell with a chemically synthesized genome and a bacterial cell with a synthetic genome encoding only the essential gene set needed for life. In reaching this milestone the Venter Institute scientists developed the fundamental techniques of the new field of synthetic genomics including genome transplantation and genome assembly. Glass was also leader of the JCVI project that rapidly made synthetic influenza virus vaccine strains in collaboration with Novartis Vaccines and Diagnostics, Inc. and Synthetic Genomics, Inc. At the JCVI he has also led the bacterial outer membrane vesicle based vaccine, genome transplantation, and Mycoplasma genitalium minimal genome projects, and projects studying other mycoplasma and ureaplasma species. Glass and his Venter Institute colleagues are now using synthetic biology and synthetic genomics approaches developed at the JCVI to create cells and organelles with redesigned genomes to make microbes that can produce biofuels, pharmaceuticals, and industrially valuable molecules. Glass is an adjunct faculty member of the University of Maryland at College Park Cellular and Molecular Biology Program, one of the founding members of the Build-A-Cell program to create synthetic cells, and member of the Global Viral Network Scientific Leadership Board.

Prior to joining the JCVI, Glass spent five years in the Infectious Diseases Research Division of the pharmaceutical company Eli Lilly. There he was a member of the hepatitis C virology group and a microbial genomics group (1998-2003). There Glass was part of the Lilly and Vertex Pharmaceuticals Inc. team that developed Incivek, one of the first drugs to cure hepatitis C virus.
Glass earned his undergraduate (Biology) and graduate degrees (Genetics) from the University of North Carolina at Chapel Hill. His Ph.D. work was on RNA virus genetics in the laboratory of Gail Wertz. He was on the faculty and did postdoctoral fellowships in the Microbiology Department of the University of Alabama at Birmingham in polio virology with Casey Morrow and mycoplasma pathogenesis with Gail Cassell (1990-1998). On sabbatical leave in Ellson Chen’s lab at Applied Biosystems, Inc. (1995-1997) he sequenced the genome of Ureaplasma parvum and began his study of bacterial genomics.

Emma Frow

Emma’s research and teaching activities focus on the governance of emerging biotechnologies, especially synthetic biology and biological engineering. She started her research life as a bioscientist, completing a PhD in biochemistry at the University of Cambridge, and then re-trained in the field of science & technology studies (STS) at the University of Edinburgh and Harvard’s Kennedy School of Government. Her current faculty position at Arizona State University is a joint appointment between the School for the Future of Innovation in Society and the School of Biological & Health Systems Engineering, which allows her to straddle the worlds of science policy and bioengineering. Emma has been studying the field of synthetic biology for a decade now, working on a variety of social scientific and interdisciplinary projects in Europe and the US. She has specific research interests in the relationship between engineering and biology, and in the standards and infrastructures (physical, digital, social) being designed to support the development of this field. She sees standards and infrastructures as tools of governance, and is interested in identifying the values, design choices and visions of the future that get built into new infrastructures for biotechnology.

Andrew Ellington

The Ellington lab works on using synthetic biology to augment organismal chemistry, generating expanded genetic alphabets and genetic codes. In addition, we attempt to developing orthogonal control systems for a variety of organisms that allow us to readily lay in new instruction sets that can operate on top of normal metabolism. Between these innovations, it has proven possible to develop and produce novel biomaterials, with the ultimate goal of being able to direct the evolution of materials properties.

Mary Dunlop

Mary Dunlop is an Associate Professor of Biomedical Engineering at Boston University with additional appointments in Molecular Biology, Cell Biology & Biochemistry and Bioinformatics. She graduated from Princeton University with a B.S.E. in Mechanical and Aerospace Engineering and a minor in Computer Science. She then received her Ph.D. from the California Institute of Technology, where she studied synthetic biology with a focus on dynamics and feedback in gene regulation. As a postdoctoral scholar, she conducted research on biofuel production at the Department of Energy’s Joint BioEnergy Institute. Her lab engineers novel synthetic feedback control systems and also studies naturally occurring examples of feedback in gene regulation. In recognition of her outstanding research and service contributions, she has received many honors including a Department of Energy Early Career Award, a National Science Foundation CAREER Award, and the ACS Synthetic Biology Young Investigator Award.

Maitreya Dunham

The Dunham lab uses synthetic biology, evolution, and genomics to understand how genome variation works in yeast and humans. In service of this goal, we also build tools, both physical devices for continuous culture and DNA gadgets for yeast genetics.

Douglas Densmore

Douglas Densmore

Lydia Contreras

Dr. Lydia M. Contreras is an Associate Professor (and Laurence E. McMakin, Jr. Centennial Fellow) of Chemical Engineering at the University of Texas-Austin; she is also a member of the Institute of Cell and Molecular Biology. She teaches Introduction to Chemical Engineering Computing, Thermodynamics, Introduction to Chemical Engineering Analysis, and Fundamental and Applications of Cellular Regulation. Dr. Contreras obtained a B.S.E. in Chemical Engineering from Princeton University, where she graduated Cum Laude. She completed her PhD in Chemical Engineering from Cornell University, focusing on engineering bacterial cells for improved production of therapeutic proteins. As a postdoctoral associate at the Wadsworth Center (New York State Department of Health), she focused on understanding mechanisms of infection in pathogenic bacteria. She began her career at the University of Texas-Austin in 2011, where she leads a research team focused on RNA biochemistry to study gene regulation mechanisms associated with stress-responses for applications in health and biotechnology. She has received several academic, teaching and service awards including: Biotechnology and Bioengineering Daniel I.C. Wang Award, Department of Thrust Reduction Agency (DTRA) Young Investigator, Airforce Office of Scientific Research Young Investigator, NSF CAREER, Health and Environmental Institute (HEI) Walter E. Rosenblith New Investigator, Norman Hackerman Advanced Research Program (NHARP) Early Career, Society of Hispanic Professional Engineers (SHPE) Young Investigator Award, and an Innovative Early-Career Frontiers of Engineering Educator. She lives in Austin, Tx with her husband Chris and is a proud mom to boy-girl twins.

James Collins

Yvonne Chen

Yvonne Chen

Dr. Yvonne Chen is an Associate Professor of Microbiology, Immunology, and Molecular Genetics at the University of California, Los Angeles. She is also a faculty, by courtesy, in the Department of Chemical and Biomolecular Engineering. The Chen Laboratory focuses on applying synthetic biology and biomolecular engineering techniques to the development of novel mammalian-cell systems. The Chen Lab’s work on engineering next-generation T-cell therapies for cancer has been recognized by the NIH Director’s Early Independence Award, the NSF CAREER Award, the Hellman Fellowship, the ACGT Young Investigator Award in Cell and Gene Therapy for Cancer, the Mark Foundation Emerging Leader Award, and the Cancer Research Institute Lloyd J. Old STAR Award. Prior to joining UCLA in 2013, Yvonne was a Junior Fellow in the Harvard Society of Fellows. She received postdoctoral training at the Center for Childhood Cancer Research within the Seattle Children’s Research Institute, and in the Department of Systems Biology at Harvard Medical School. Yvonne received her B.S. in Chemical Engineering from Stanford University and her Ph.D. in Chemical Engineering from the California Institute of Technology.

Matthew Chang

Michelle Chang

James Carothers

The Carothers Research Group at the University of Washington creates design-driven approaches for synthetic biology that integrate quantitative RNA aptamer device design, dynamic control system modeling, and CRISPR-Cas network engineering to investigate questions about biological design and develop technologies for bio-based chemical synthesis. Previously, Carothers was a postdoctoral fellow with pioneering synthetic biologist Jay D. Keasling at UC Berkeley. Carothers earned a Ph.D. at Harvard University with Nobel Prize winner Jack W. Szostak. He has a B.S. in Molecular Biophysics and Biochemistry from Yale. His work has been recognized by the UW Presidential Innovation Award and the Alfred P. Sloan Research Fellowship, and supported by the NSF, DOE and private industry. He has been awarded the UW College of Engineering Junior Faculty Award and is a Dan Evans Career Development Professor.

Adam Arkin

Mark Styczynski

Mark received a B.S. in chemical engineering from the University of Notre Dame in 2002 and a Ph.D. in Chemical Engineering from MIT in 2007. He also did postdoctoral work at the Broad Institute from 2007-2009. At Georgia Tech, Mark’s work spans synthetic and systems biology, and often includes work at the intersection of those two fields. His main Engineering Biology focus is on the development of low-cost, low-resource diagnostics.

Pamela Silver

Pamela Silver

Vincent Noireaux

Vincent Noireaux got his B.Sc. in applied physics at the University of Tours (France) in 1994. In 1995 he moved to Paris for physics graduate school at the University Paris 11 (Orsay). He did his PhD at the Curie Institute (Paris, 1996-2000) in biological physics in the laboratory of Jacques Prost on the motion of the bacterium Listeria. He studied the actin cytoskeleton mechanisms involved in cell motility and learned the biology related to this project in the laboratory of Daniel Louvard. In 2000 he joined the laboratory of Albert Libchaber at the Rockefeller University in New York City where he spent five years as a postdoc. He used cell-free expression systems to construct elementary gene networks and synthetic cell systems. In 2005, he moved to the University of Minnesota where he is pursuing his work in synthetic biology using cell-free expression. His research consists of constructing and characterizing biochemical systems by executing synthetic DNA programs in vitro, from simple regulatory elements to synthetic cells.

Joshua Leonard

Julius Lucks

Julius B. Lucks is Associate Chair and Professor of Chemical and Biological Engineering at Northwestern University. Research in the Lucks Lab asks fundamental questions about the molecules of life. They are particularly fascinated by how RNA, DNA’s close chemical cousin, acts as a mini molecular computer inside cells, allowing it to continuously monitor the status of itself and its environment. They then translate newly discovered fundamental knowledge into new ways to engineer biological systems for the health of ourselves and the planet, with recent applications to sustainable biomanufacturing and low cost water quality diagnostics.

For his research, Professor Lucks has been recognized with a number of awards including a DARPA Young Faculty Award, an Alfred P. Sloan Foundation Research Fellowship, an ONR Young Investigator Award, an NIH New Innovator Award, an NSF CAREER award, the ACS Synthetic Biology Young Investigator Award, and most recently a Camille-Dreyfus Teacher Scholar Award. Professor Lucks is also heavily invested in helping to train the next generation of scientists and engineers through his co-founding of the Cold Spring Harbor Synthetic Biology Summer Course and his roles as a founding board member of the Engineering Biology Research Consortium. Please visit http://luckslab.org or on twitter @luckslab for more information.

Natalie Kuldell

Dr. Natalie Kuldell leads BioBuilder, a nonprofit organization that inspires the next generation of innovators with authentic science and engineering. BioBuilder’s synthetic biology curriculum breeds excitement by helping students and teachers design and then build
biotechnologies that solve real problems throughout the US and around the world. A BioBuilder textbook was published by O’Reilly Media. In 2017, BioBuilder opened a community lab in Kendall Square’s LabCentral.

Dr. Kuldell studied Chemistry as an undergraduate at Cornell, completed her doctoral and post-doctoral work at Harvard Medical School, and taught at Wellesley College before joining the Department of Biological Engineering faculty at MIT in 2003. She is the 2020 recipient of the Margret and H.A. Rey Curiosity Award.

Eric Klavins

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