Profiles

  • Bojing Jiang

    Bojing Jiang is a Ph.D. candidate in Biomedical Engineering at Washington University in St. Louis, with a focus on developing protein-based materials for biomedical and environmental applications. Her research integrates synthetic biology, materials science, and tissue engineering to create innovative biomaterials for regenerative medicine, drug delivery, and micro-nanofabrication. Bojing’s work emphasizes sustainability and biocompatibility, leveraging fully protein-based materials to design eco-friendly alternatives with enhanced functionality.

    She has contributed to groundbreaking projects funded by the National Institutes of Health (NIH), including materials for neuron regeneration, vascular repair, and wound healing. Bojing has published in high-impact journals such as Science Advances and Advanced Functional Materials, with her research recognized for its role in advancing green and scalable nanofabrication techniques using protein-based resists.

    In addition to her technical expertise, Bojing excels in protein design, gene editing, fermentation, and biomaterials characterization, with a commitment to developing solutions that bridge scientific innovation and real-world impact. She is passionate about contributing to the next generation of healthcare technologies while advancing sustainability in the field of biomedical engineering.

  • Sara Molinari

    Dr. Sara Molinari graduated from the Systems, Synthetic and Physical Biology Ph.D. program at Rice University with a thesis on programming differentiation in bacteria. This work enabled the creation of a novel pattern formation by physically separating genetically distinct cells. As a postdoctoral researcher, she created the first de novo macroscopic living material that grows from engineered bacteria. This work presents the only genetically encoded synthetic matrix that hierarchically assembles cells over four orders of magnitude and allows the genetic control of ELM mechanical and catalytic properties. In her laboratory in the Department of Bioengineering at The University of Maryland College Park, she investigates the design rules for engineering de novo ELMs from different bacteria to enable a wide array of applications. Sara is a full member of the Sigma Xi Scientific Research Honor Society, a 2022 Distinguished Young Scholar (UWDYSS), a 2022 BME Future Faculty, and a rising star at the SynBYSS seminar series.

  • Wheaton Schroeder

    Wheaton Schroeder is a new Assistant Professor at Washington State University in the Voiland School of Chemical Engineering and Bioengineering (started in August 2024). His research lab specializes in computational metabolic modeling (often referred to as genome-scale modeling) with various applications. Emerging applications in his research includes studying neurometabolic coupling (through the Astrocyte-Neuron Lactate Shuttle) including its role in seizures and designing an inducible cyanobacteria bioproduction platform leveraging the heterogeneity in photobioreactors for division of labor. Previous to his current position, Wheaton was most recently a Postdoctoral Scholar in the Department of Chemical Engineering at the Pennsylvania State University advised by Costas D. Maranas (for three years). In this position, his research, still in systems biology, was funded by the Center for Bioenergy Innovation (CBI). In CBI, his research focused on fundamental understanding of the target organism for consolidated bioprocessing, Clostridium thermocellum, and improved phenotype of process feedstock, Populus tricocarpa. In this role, he worked closely with synthetic biologists for hypothesis testing and model validation. Wheaton earned his Ph.D. in Chemical and Biomolecular Engineering at the University of Nebraska – Lincoln, advised by Rajib Saha. In his doctoral studies, Wheaton applied mathematical modeling to designing and modeling genetic circuits, creating a lifecycle model for the model plant Arabidopsis thaliana, studying fungal melanogenesis, and studying nitrogen-stressed maize root metabolism, among other application. Given this diversity of application, his thesis was entitled “Creation and Application of Various Tools for the Reconstruction, Curation, and Analysis of Genome-Scale Models of Metabolism”, defended in June of 2021. Wheaton earned a Bachelors degree in Chemical Engineering and Mathematics at Iowa State University in May of 2015.

  • Leopold Green

    Leo Green is an assistant professor of biomedical engineering at Purdue University. His research program converges DNA nanotechnology, microbiome engineering, and computational models to design bacterial theanostics.

  • James Saenz

    Research Summary
    My lab’s research merges my unique background in geochemistry and microbiology and my interest in synthetic biology and bioengineering to unravel and harness the role of lipids in organizing bioactivity. My lab has recently pioneered two fronts:

    1. Minimal Microbial Models for Membrane Biology: We’ve established minimal bacterial systems, notably pathogenic mycoplasma and the Minimal Cell (JCVI-Syn3), as modifiable membrane platforms amenable to synthetic genomics. This approach allows us to dissect and manipulate cell membranes, offering unique insights into lipid-mediated cellular functions and interactions. We have developed approaches to tune and minimize mycoplasma and Syn3 lipidomes, demonstrating that two lipids are sufficient (but far from optimal) for life. Using these minimal bacterial organisms, we can reintroduce genomic and chemical complexity to elucidate the crucial components of a functional cell membrane, with the ultimate goal of designing bespoke synthetic cell membranes. Expanding from studies of individual lipids, we aim to understand and engineer the lipidome’s complexity and its impact on cellular behavior in the context of environments from mammalian hosts to oceans and soils.

    2. Novel Membrane Sense and Response Mechanisms based on RNA-Lipid Interactions: A groundbreaking direction in our research is exploring how lipids can selectively interact with, and modulate RNAs. Beyond exploring lipid functions, this work paves the way for developing RNA-lipid interactions to create synthetic membrane sensors and riboregulatory mechanisms. The potential to design lipid-sensitive RNAs opens new avenues for synthetic biology applications, including novel forms of lipid regulation and membrane homeostasis.

  • Jonathan Klonowski

    Jonathan is a policy postdoctoral researcher at the Engineering Biology Research Consortium focusing on biosecurity and simulating the bioeconomy. Earning is PhD from the University of Pittsburgh School of Medicine, Jonathan used an interdisciplinary approach to explore the complexities of developmental diseases employing biological and computational methods. Transitioning into policy, Jonathan now aims to leverage his expertise and leadership to drive evidence-based policy at the intersection of biotechnology, national security and society to ensure inclusive solutions for society’s most pressing challenges.

    During graduate school, Jonathan led Allegheny Science Policy and Governance for five years, promoting the role of science in public policy. He organized over 15 Science Policy, Advocacy, Communication and Diplomacy (Sci-PACD) events, mentored 10 early-career scientists, and published several policy manuscripts that contributed to the engagement of scientists in policy. Jonathan Is also a member of the National Science Policy Network, where he launched and managed two grants amplifying the voices of minority communities in Sci-PACD.

    In 2023, Jonathan consulted for the Special Competitive Studies Project — a think tank focused on U.S. competitiveness in the technology sector — utilizing his strengths as an adaptable analyst also capable of uniting stakeholders. There, he authored a public-private moonshot action plan to foster innovation in biotechnology by creating an open-source genetic library that encompasses global biodiversity. His work contributed to initiatives that aim to enhance national security and competitiveness by promoting collaboration across the Vannevar Bush Triangle.

  • Sana Zakaria

    Sana Zakaria is a Research Leader, and a Global RAND Scholar working emerging technologies and their intersection. Her work focusses on assessing the societal and biosecurity implications of technological advancement, and unpacking the factors affecting technology demand and supply, assessing oversight mechanisms for technology, and building resilience and preparedness in society.
    She is currently leading on evaluating the PATH-SAFE programme, a pilot programme on interconnectivity of the UK-wide genomic
    biosurveillance ecosystem. She is working with UK MoD on bioattribution workflows and capacity building. Her other key project involves assessing oversight mechanisms in embryology, brain computer interfaces, engineering biology and organoids. She is also leading on a project developing a global risk index to manage dual use risks from AI powered biological tools. She currently sits on an expert scientific group to the BWC to provide expert advice on science and technology mechanism, compliance and verification and international cooperation and assistance.

  • George Church

    Harvard PhD 1984. Professor at Harvard & MIT 1986, co-author of 716 papers, 164 patent publications & book “Regenesis”; developed methods used for the first genome sequence (1994) & 10M-fold cost reduction (fluor-NGS & nanopores), molecular barcoding/ multiplexing, DNA assembly from chips, genome editing/writing/recoding; co-initiated BRAIN Initiative (2011) & Genome Projects (GP-Read-1984, GP-Write-2016, PGP-2005:first open-access personal/precision medicine data & cells); machine learning for protein engineering, tissue reprogramming, organoids, gene therapy, aging reversal, xeno-transplantation, in situ 3D DNA/RNA/protein imaging.

  • P. C. Dave P. Dingal

    My research focuses on the interplay between extrinsic and intrinsic signals that affect cell behavior by building cutting-edge molecular tools to measure and perturb such signals. Most molecular tools are being developed and function well in vitro. Current technologies are unable to measure signaling in its native context in vivo, mainly due to lack of signal amplification, slow kinetics, and incompatibility of reagents. I aim to develop and translate some of these tools in vivo to help solve issues of biomedical relevance.

    My graduate training combined biophysical and systems-biology approaches for the mechano-chemical control of adult human stem cells.With my engineering background, my postdoctoral fellowship at Stanford University focused on developing synthetic biological tools to measure signals that induce cell fate. I developed a versatile receptor-based tool called CRISPR ChaCha, which senses the immediate microenvironment and activate novel genomic expression programs via CRISPR-Cas9. At Harvard University, I created molecular tools that control the secretion and sensing of signals as they arise in the developing zebrafish embryo.

    As an Assistant Professor at UT Dallas, my research laboratory is developing cutting-edge tools to measure and characterize signaling mechanisms in vivo. We are developing innovative uses of biological molecules in vivo, including CRISPR/Cas systems, synthetic proteases, and fluorescent probes to gain deeper insights into endogenous signal release and response in early embryos and in the brain.

  • Chris Vaiana

  • Erin Garza

    Dr. Garza received her master’s and PhD in microbiology from Northern Illinois University. Her graduate work involved genetically engineering biofuel pathways, like homoethanol and butanol, into Escherichia coli. Dr. Garza completed a postdoc at the J. Craig Venter Institute (JCVI) where she is currently a staff scientist in the synthetic biology department. Her research involves genetically engineering bacteria and diatoms to produce compounds of interest, elucidating plastic degradation pathways in marine organisms, domesticating and characterizing genetic parts for DNA cloning libraries, and developing and optimizing cloning techniques for non-model organisms.

    Dr. Garza has worked on numerous research projects, but her main interest involves studying the microbiome of deep-sea plastics in an attempt to locate and engineer new plastic degrading organisms and to determine the effects of plastic pollution on the ocean and its ecology. She is currently working towards attaining an assistant professor position at JCVI.

  • Christian Cuba Samaniego

    I received my BS degree in Mechatronic Eng. from National University of Engineering (UNI-Peru). I obtained my PhD in Mechanical Engineering from the University of California Riverside (UCR) under the supervision of Elisa Franco in 2017. I held a postdoctoral scholar with Ron Weiss at MIT (2017), Elisa Franco at UCLA (2019), Ming-Ru Wu at Harvard/DFCI (2023). In Fall 2024, I will join the Computational Biology Department at Carnegie Mellon University. I work at the intersection among Control Theory, Systems Biology and Synthetic Biology. I am specially interested in the design, analysis and applications of biomolecular feedback control systems and molecular neural networks for decision-making in living cells. To create a community that connects mathematical theories, models, and biomolecular experiments, I co-organize a Seminar on Biological Control Systems. it focuses on applications of mathematical modeling and control systems to biology. We host monthly talks featuring our members and invited guests.

  • Johnathan O’Neil

    Johnathan is a postdoctoral scholar at the Engineering Biology Research Consortium (EBRC). He earned his Ph.D. in Chemical and Biomolecular Engineering from Georgia Tech, where his research centered on the biomechanics and fluid dynamics of semiaquatic insects’ locomotion with potential applications in robotics. His fieldwork included studying these insects in Georgia and the Peruvian Amazon. During graduate school, he actively engaged in outreach events in both Atlanta and Peru. Outside of research, Johnathan enjoys writing poetry and collecting vinyl records.

  • Elizabeth Allen

    Elizabeth is a U.S. Coast Guard Veteran who spent 12 years as a Food Service Officer. She joined EBRC as a Senior Administrator in August 2024. She has most recently been a contract Executive Assistant with First Republic Bank and FEMA. She has a B.S. in Hospitality Management from Johnson & Wales University. She is an avid book reader and crossfitter. You can find her hiking the Bay Area on the weekends with her husband and three kids.

  • Garrett Dunlap

    Dr. Garrett Dunlap joined EBRC as Associate Director of Policy & International Engagement in September 2024. Before this, he was Head of Science and Innovation at the British Consulate-General in New York, fostering UK-US science and tech collaborations. He previously worked as a Graduate Fellow at the Wilson Center, focusing on biosecurity risks from converging technologies, and as a Science Diplomacy Fellow with the Netherlands Innovation Network, exploring deep tech innovation ecosystems. In addition to his current role, Garrett is a Fellow for Ending Bioweapons with the Council on Strategic Risks, and he also participates in working groups for the World Economic Forum and All Tech is Human. He holds a Ph.D. in Biological and Biomedical Sciences from Harvard University and undergraduate degrees in Biology and Political Science from Case Western Reserve University.

  • Jaya Joshi

    Jaya Joshi is an Assistant Professor in the Department of Wood Science, Bioproducts, and Bioengineering at the University of British Columbia in Vancouver, Canada. Her research walks through enzyme design space: exploring fitness landscapes for radical metabolic engineering design ideas, with the goal of achieving successful carbon farming by 2050. The overarching aim of her research program is to transform inefficient designer biocatalysts into highly active enzymes by applying novel enzyme improvement strategies, such as continuous directed evolution and machine learning. Jaya earned her PhD in Cell and Molecular Biology from Western University and Agriculture and Agri-Food Canada in 2017. She completed her postdoctoral fellowship with Dr. Andrew Hanson at the University of Florida in 2020 before joining Dr. Vincent Martin’s lab at the Centre for Structural and Functional Genomics in Montreal, where she explored the immense potential of biofoundries in synthetic biology. Exploring automation and synthetic biology tool development remains central to Jaya’s research at the University of British Columbia.

  • Michaelle Mayalu

    Dr. Michaëlle N. Mayalu is an Assistant Professor of Mechanical Engineering. She received her Ph.D., M.S., and B.S., degrees in Mechanical Engineering at the Massachusetts Institute of Technology. She was a postdoctoral scholar at the California Institute of Technology in the Computing and Mathematical Sciences Department. She was a 2017 California Alliance Postdoctoral Fellowship Program recipient and a 2019 Burroughs Wellcome Fund Postdoctoral Enrichment Program award recipient. She is also a 2023 Hypothesis Fund Grantee.
    Dr. Michaëlle N. Mayalu’s area of expertise is in mathematical modeling and control theory of synthetic biological and biomedical systems. She is interested in the development of control theoretic tools for understanding, controlling, and predicting biological function at the molecular, cellular, and organismal levels to optimize therapeutic intervention.

  • Virginia Cornish

    Virginia W. Cornish is the Helena Rubinstein Chair in the Department of Chemistry and a founding member of the Department of Systems Biology at Columbia University. Her research brings together modern methods in synthetic chemistry and DNA technology to expand the synthetic capabilities of living cells, and she is a pioneer in the field of yeast synthetic biology. Her current research focuses on translating state-of-the-art synthetic biology platforms to the clinic. She has over 100 research publications and issued patents and has been supported by grants from the NIH, NSF, DARPA, USDA, and numerous private foundations. Virginia has been recognized by an NSF Career Award (2000), a Sloan Foundation Fellowship (2003), the Columbia College John Jay Award (2005), the Protein Society Irving Sigal Young Investigator Award (2009), the American Chemical Society Pfizer Award in Enzyme Chemistry (2009), and an HHMI Gilliam Adviser (2021). She graduated summa cum laude from Columbia University with a B.A. in Biochemistry in 1991, where she did undergraduate research with Professor Ronald Breslow. She earned her Ph.D. in Chemistry with Professor Peter Schultz at the University of California at Berkeley and then was a Postdoctoral Fellow in the Biology Department at M.I.T. under the guidance of Professor Robert Sauer. Virginia joined the faculty of the Chemistry Department at Columbia in 1999 and was promoted Associate Professor with tenure in 2004, Professor in 2007, and Helena Rubinstein Chair in 2011.

  • Alexander Vlahos

    Alexander Vlahos is an incoming Assistant Professor in the Department of Biomedical Engineering at the Georgia Institute of Technology. He is currently a Human Frontier Science Program Fellow in the laboratory of Dr. Xiaojing Gao at Stanford University where he applies principles in synthetic biology and protein engineering to develop tools for programming intercellular signalling. Previously, he completed his PhD in Biomedical Engineering with Dr. Michael Sefton at the University of Toronto, where he developed platforms to improve vascularization of the subcutaneous space for islet transplantation. His goal is to converge his background in synthetic biology, systems biology, and tissue engineering to mechanistically study and manipulate multicellular systems to determine the key signals that govern these processes. His lab will focus on grandstanding challenges in biomedicine such improving the long-term engraftment of therapeutic cells, and increasing the efficacy of cancer immunotherapies.

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