Profiles

  • Michaelle Mayalu

    Dr. Michaëlle N. Mayalu is an Assistant Professor of Mechanical Engineering. She received her Ph.D., M.S., and B.S., degrees in Mechanical Engineering at the Massachusetts Institute of Technology. She was a postdoctoral scholar at the California Institute of Technology in the Computing and Mathematical Sciences Department. She was a 2017 California Alliance Postdoctoral Fellowship Program recipient and a 2019 Burroughs Wellcome Fund Postdoctoral Enrichment Program award recipient. She is also a 2023 Hypothesis Fund Grantee.
    Dr. Michaëlle N. Mayalu’s area of expertise is in mathematical modeling and control theory of synthetic biological and biomedical systems. She is interested in the development of control theoretic tools for understanding, controlling, and predicting biological function at the molecular, cellular, and organismal levels to optimize therapeutic intervention.

  • Virginia Cornish

    Virginia W. Cornish is the Helena Rubinstein Chair in the Department of Chemistry and a founding member of the Department of Systems Biology at Columbia University. Her research brings together modern methods in synthetic chemistry and DNA technology to expand the synthetic capabilities of living cells, and she is a pioneer in the field of yeast synthetic biology. Her current research focuses on translating state-of-the-art synthetic biology platforms to the clinic. She has over 100 research publications and issued patents and has been supported by grants from the NIH, NSF, DARPA, USDA, and numerous private foundations. Virginia has been recognized by an NSF Career Award (2000), a Sloan Foundation Fellowship (2003), the Columbia College John Jay Award (2005), the Protein Society Irving Sigal Young Investigator Award (2009), the American Chemical Society Pfizer Award in Enzyme Chemistry (2009), and an HHMI Gilliam Adviser (2021). She graduated summa cum laude from Columbia University with a B.A. in Biochemistry in 1991, where she did undergraduate research with Professor Ronald Breslow. She earned her Ph.D. in Chemistry with Professor Peter Schultz at the University of California at Berkeley and then was a Postdoctoral Fellow in the Biology Department at M.I.T. under the guidance of Professor Robert Sauer. Virginia joined the faculty of the Chemistry Department at Columbia in 1999 and was promoted Associate Professor with tenure in 2004, Professor in 2007, and Helena Rubinstein Chair in 2011.

  • Alexander Vlahos

    Alexander Vlahos is an incoming Assistant Professor in the Department of Biomedical Engineering at the Georgia Institute of Technology. He is currently a Human Frontier Science Program Fellow in the laboratory of Dr. Xiaojing Gao at Stanford University where he applies principles in synthetic biology and protein engineering to develop tools for programming intercellular signalling. Previously, he completed his PhD in Biomedical Engineering with Dr. Michael Sefton at the University of Toronto, where he developed platforms to improve vascularization of the subcutaneous space for islet transplantation. His goal is to converge his background in synthetic biology, systems biology, and tissue engineering to mechanistically study and manipulate multicellular systems to determine the key signals that govern these processes. His lab will focus on grandstanding challenges in biomedicine such improving the long-term engraftment of therapeutic cells, and increasing the efficacy of cancer immunotherapies.

  • Luis Joel Figueroa-Yáñez

    PhD. Luis Joel Figueroa-Yáñez is Researcher class A, repatriated, belongs to the National System of Researchers (Level I), assigned to the Center for Research and Assistance in Technology and Design of Jalisco State (CIATEJ), México.
    He has a Bachelor’s degree in Biology from the Universidad Veracruzana, a Master’s degree in Bioethics from the Universidad Anáhuac, a PhD in Biological Sciences from the Yucatán Scientific Research Center and a postdoctoral degree at the Donald Danforth Plant Science Center, St. Louis Missouri, United States of America.
    It has publications on:
    -CRISPR-Cas and pathogenic organisms
    -Neural networks, deep learning and artificial intelligence in pancreatic cancer
    -The DBTL paradigm in Synthetic Biology and Synthetic Biology and COVID-19
    -Antioxidants and type 2 diabetes mellitus
    -Improvement of plants to counteract the greenhouse effect and other factors
    -CRISPR-Cas9 and dCas9 in yeast

  • Sebastian Rivera

    Sebastian Rivera is a Science Policy Postdoctoral scholar at the Engineering Biology Research Consortium. Prior to EBRC, he was a NIH Chemistry-Biology Interface Training Fellow at the University of Michigan, where his research focused on identifying and characterizing fungal enzymes responsible for the biosynthesis of drug-like molecules. Additionally, he received a certificate in Science, Technology, and Public Policy through the Ford School of Public Policy at the University of Michigan. His interests lie in policy and security considerations for the responsible development and release of computational tools for designing proteins and other macromolecules for engineering biology. When he isn’t working, Sebastian is rock climbing, playing the latest RPGs, or exploring the local food scene.

  • Otto Cordero

    Otto X. Cordero received a B.S. in computer and electrical engineering from the Polytechnic University of Ecuador, an M.Sc. in artificial intelligence from Utrecht University, and a Ph.D. in theoretical biology, also from Utrecht University. In 2014 Cordero received the ERC Starting grant in Europe and in 2015 he moved to MIT, where he has since been a member of the faculty. Cordero is a past Sloan Fellow in Ocean Sciences and recipient of the Simons Early Career Award in Marine Microbial Ecology. In 2017, Cordero co-founded PriME, a new Simons Collaboration that brings together physicists, biologists and engineers to decipher the rules that govern the assembly and functioning of marine microbial ecosystems.

  • Maobing Tu

    Dr Maobing Tu is a professor in the Department of Chemical and Environmental Engineering at the University of Cincinnati. He received his PhD degree in Forestry Bioenergy at the University of British Columbia (2007). Dr. Tu is a recipient of Industrial R&D Fellowship from Natural Science and Engineering Research Council of Canada (NSERC) and an NSF CAREER award in 2013. His research is centered on the development of cost-effective processes for producing biofuels and chemicals from renewable resources and waste. Specifically, he focuses on the interface between biomass processing chemistry and biochemical engineering in the production of fuels, chemicals and biomaterials. He has published more than 60 papers and received funding from NSF, DOE and EPA.

  • Jonathan Conway

    Dr. Jonathan Conway earned his B.S. in Chemical Engineering at the University of Notre Dame and his M.S. and Ph.D. in Chemical Engineering at North Carolina State University under the guidance of Dr. Robert Kelly, focusing on lignocellulose degradation by extremely thermophilic bacteria. After completing his Ph.D., he trained as a postdoctoral researcher at the University of North Carolina – Chapel Hill in Dr. Jeff Dangl’s lab, where he worked on engineering the plant root microbiome.

    In 2021, Dr. Conway established his independent lab in the Chemical & Biological Engineering department at Princeton University. He is also an associated faculty member of the Omenn-Darling Bioengineering Institute, the Andlinger Center for Energy and the Environment, and the High Meadows Environmental Institute. The Conway lab focuses on genetically engineering non-model bacteria at plant-microbe interfaces. By mechanistically defining and engineering plant-microbe interactions, the lab aims to develop technologies for the bio-agriculture, bio-energy, and bio-chemical industries.

  • Marie Migaud

    I am a French-trained Chemist/Chemical Engineer with a PhD in organic synthesis from Michigan State University, postdoctoral training at the University of Bath and Oxford. My first independent academic position was at Queen’s University Belfast (Chemistry) in 2000. I was appointed first in faculty of science and engineering, then requested a joint appointment with the Center for Cell Biology and Cancer Research, and ultimately moved to the School of Pharmacy to fully exploit the collaborative network that my moving within the institution had allowed me to create. In 2016, I left my permanent UK academic position to join the Mitchell Cancer Institute at the University of South Alabama, after a sabbatical year in the department of Biochemistry at the Carver College of Medicine in Iowa. I seek to accelerate translational research programs through basic research in chemical biology and synthetic chemistry.
    More specifically, I pursue chemical research on canonical and non-canonical nucleotides and dinucleotides in the context of cell bioenergetics and signaling. I direct biology-focused research projects supported by bespoke organic synthesis and knowledge-based metabolomics and RNA/DNAomics research. My laboratory’s activities focus on synthesizing nucleosidic isotopologues, nucleotide-derived cofactors, and catabolites and develop analytical platforms that help unravel their role in diseases linked to genomic and metabolic mitochondrial dysfunction. Key to our research efforts are novel synthetic methodologies of isotopically labeled and modified nucleos/tides using mechanochemistry to allow atom-efficient syntheses.

  • Carolyn Chapman

    Carolyn Riley Chapman, PhD MS, joined the Multi-Regional Clinical Trials Center of Brigham and Women’s Hospital and Harvard (MRCT Center) in October 2023 (mrctcenter.org). She is a Member of the Faculty of the Department of Medicine at Harvard Medical School and Lead Investigator in the Division of Global Health Equity (DGHE), Department of Medicine, Brigham and Women’s Hospital. Her work involves collaboration with diverse stakeholders to identify and address challenges in the research and development of genetic technologies and precision medicine, including cell and gene therapies. Since April 2023, Dr. Chapman serves as Co-Chair of the ELSI-Dedicated Genome Engineering Workgroup at the Center for Synthetic Regulatory Genomics (SyRGe), led by Dr. Jef Boeke, the Sol and Judith Bergstein Director of the Institute of Systems Genetics and Professor, Department of Biochemistry and Molecular Pharmacology, at NYU Grossman School of Medicine. Prior to joining the MRCT Center, Carolyn worked at NYU Grossman School of Medicine in various roles. Immediately before joining the MRCT Center, she was Faculty in the Center for Human Genetics and Genomics at NYU Grossman School of Medicine with a primary appointment as Research Assistant Professor in the Department of Population Health (Division of Medical Ethics). In the past, Carolyn has worked as an Associate/Lecturer and as Interim Associate Director for the Columbia Bioethics program; as a business strategy management consultant in the biopharmaceuticals industry at L.E.K. Consulting; at a start-up biopharmaceutical company, Aton Pharma; and as a freelance science/medical writer. Carolyn graduated summa cum laude from Dartmouth College with a BA in Biology. She has a PhD in Genetics from Harvard University and an MS in Bioethics from Columbia University. She completed a postdoctoral fellowship in medical ethics at NYU Grossman School of Medicine and a Graduate Certificate in Survey Research at UConn’s School of Public Policy.

  • Javin Oza

    Engineering of cell-free systems, proteins & enzymes, and adopting bioengineering to the university classroom

  • Julietta Sheng

    Julietta Sheng is a Science Policy postdoctoral scholar at the Engineering Biology Research Consortium. Prior to EBRC, she was a Junior Fellow at Colorado State University in collaboration with Massachusetts General Hospital – Boston and partnered with bioengineers, clinicians, and academics to enhance evidence-based research, identify scientific challenges, and develop creative solutions. She recently earned her PhD in Biomedical Sciences – Neuroscience from Colorado State University with a focus on sex differences in the brain and body that lead to neuropsychiatric disorders. Outside of work, Julietta likes to play pickleball, read psychological thrillers, and go on long walks with her puppos.

  • Neil Dalvie

    Neil Dalvie did his PhD in Chemical Engineering at MIT, studying therapeutic protein manufacturing. Now, he is a Schmidt Science Fellow in the Synthetic Biology Hive at Harvard Medical School. Neil researches large-scale bioprocessing for mineral processing and is interested in the ethics and regulation of environmental bioengineering.

  • Cameron Roots

    Cameron is a recent graduate and postdoctoral fellow in the Barrick Lab at the University of Texas at Austin. He completed his B.S. in biochemistry and in molecular, cellular, and developmental biology at the University of Washington. Afterwards, he completed a postbactorial study at the National Institutes of Health as an IRTA fellow. His current research is at the intersection of synthetic and evolutionary biology, exploring how engineered systems are prone to mutation and developing tools to help researchers keep theirs stable. His prior policy activities include institutional policy initiatives within the UT Austin Interdisciplinary Life Sciences programs; independent study and programming as a Graduate Archer Fellow; and as an intern on biomanufacturing, biosecurity, and AIxBio federal policy.

  • Efrain Rodriguez-Ocasio

    Efrain Rodriguez Ocasio is originally from Puerto Rico and graduated from the University of Puerto Rico-Mayagüez with a B.S. in Industrial Biotechnology. During his undergraduate studies, Efrain served as a trustee on the Governing Board of the University of Puerto Rico, which oversees the 11 campuses of Puerto Rico’s public University. He earned his Ph.D. in Chemical Engineering at Iowa State University, where he developed microbial platforms for plastic waste upcycling and earned the ISU Research Excellence Award. Efrain is currently a postdoctoral fellow at the Great Lakes Bioenergy Research Center and the University of Wisconsin-Madison. His research integrates metabolic and process modeling to identify new production targets for the decarbonization of the chemical industry and synthetic biology for industrial strain development.

  • Ross Klauer

    Ross Klauer is a PhD candidate in Chemical and Biomolecular Engineering at the University of Delaware. He received his Bachelor of Science Degree in Chemical Engineering from Rose-Hulman Institute of Technology. Ross is co-advised by Dr. Mark Blenner and Dr. Kevin Solomon. Ross’ research focuses on elucidating the polyethylene deconstruction pathway in the digestive system of plastic-eating yellow mealworms. He is working to identify and engineer enzymes for polyethylene deconstruction. Outside of lab, Ross enjoys playing soccer and is a competitive cornhole player.

  • Rabia Yazicigil

    Rabia Yazicigil is an Assistant Professor of ECE Department at Boston University. She was a Postdoctoral Associate at MIT and received her Ph.D. degree from Columbia University in 2016. Her research focuses on the development of Cyber-Secure Biological Systems, leveraging living sensors constructed from engineered biological entities seamlessly integrated with custom-designed semiconductor chips. This unique synergy harnesses the advantages of biology while incorporating the reliability and communication infrastructure of electronics, offering a unique solution to societal challenges in healthcare, environmental monitoring, and sustainable biomanufacturing. She has received numerous awards, including the NSF CAREER Award (2024), Early Career Excellence in Research Award for the Boston University College of Engineering (2024), the Catalyst Foundation Award (2021), Boston University ENG Dean Catalyst Award (2021), and “Electrical Engineering Collaborative Research Award” for her Ph.D. research (2016). She was selected as a member of the 2024 National Academy of Engineering (NAE) US Frontiers of Engineering (USFOE) cohort.

  • Reza Zadegan

  • R. Clay Wright

    Clay Wright is an Assistant Professor in the Department of Biological Systems Engineering at Virginia Tech. His lab focuses on understanding and engineering chemical signaling pathways from plants and fungi. Clay received his BS in Chemical and Biomolecular Engineering from North Carolina State University and PhD in the same from Johns Hopkins University, where he worked with Professor Marc Ostermeier to engineer cancer therapeutic enzymes that are selectively active in the presence of a cancer marker. For his postdoctoral research, he worked with Professors Jennifer Nemhauser and Eric Klavins at University of Washington to study evolution and function of receptors for auxin, a critical plant growth hormone. Clay was recently awarded an NIH MIRA to further our understanding and engineering of chemically activated ubiquitin ligases, such as those that coordinate auxin signaling and other plant hormone signaling pathways.

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