Security WG

Virginia Cornish

Virginia W. Cornish is the Helena Rubinstein Chair in the Department of Chemistry and a founding member of the Department of Systems Biology at Columbia University. Her research brings together modern methods in synthetic chemistry and DNA technology to expand the synthetic capabilities of living cells, and she is a pioneer in the field of yeast synthetic biology. Her current research focuses on translating state-of-the-art synthetic biology platforms to the clinic. She has over 100 research publications and issued patents and has been supported by grants from the NIH, NSF, DARPA, USDA, and numerous private foundations. Virginia has been recognized by an NSF Career Award (2000), a Sloan Foundation Fellowship (2003), the Columbia College John Jay Award (2005), the Protein Society Irving Sigal Young Investigator Award (2009), the American Chemical Society Pfizer Award in Enzyme Chemistry (2009), and an HHMI Gilliam Adviser (2021). She graduated summa cum laude from Columbia University with a B.A. in Biochemistry in 1991, where she did undergraduate research with Professor Ronald Breslow. She earned her Ph.D. in Chemistry with Professor Peter Schultz at the University of California at Berkeley and then was a Postdoctoral Fellow in the Biology Department at M.I.T. under the guidance of Professor Robert Sauer. Virginia joined the faculty of the Chemistry Department at Columbia in 1999 and was promoted Associate Professor with tenure in 2004, Professor in 2007, and Helena Rubinstein Chair in 2011.

Carolyn Chapman

Carolyn Riley Chapman, PhD MS, joined the Multi-Regional Clinical Trials Center of Brigham and Women’s Hospital and Harvard (MRCT Center) in October 2023 (mrctcenter.org). She is a Member of the Faculty of the Department of Medicine at Harvard Medical School and Lead Investigator in the Division of Global Health Equity (DGHE), Department of Medicine, Brigham and Women’s Hospital. Her work involves collaboration with diverse stakeholders to identify and address challenges in the research and development of genetic technologies and precision medicine, including cell and gene therapies. Since April 2023, Dr. Chapman serves as Co-Chair of the ELSI-Dedicated Genome Engineering Workgroup at the Center for Synthetic Regulatory Genomics (SyRGe), led by Dr. Jef Boeke, the Sol and Judith Bergstein Director of the Institute of Systems Genetics and Professor, Department of Biochemistry and Molecular Pharmacology, at NYU Grossman School of Medicine. Prior to joining the MRCT Center, Carolyn worked at NYU Grossman School of Medicine in various roles. Immediately before joining the MRCT Center, she was Faculty in the Center for Human Genetics and Genomics at NYU Grossman School of Medicine with a primary appointment as Research Assistant Professor in the Department of Population Health (Division of Medical Ethics). In the past, Carolyn has worked as an Associate/Lecturer and as Interim Associate Director for the Columbia Bioethics program; as a business strategy management consultant in the biopharmaceuticals industry at L.E.K. Consulting; at a start-up biopharmaceutical company, Aton Pharma; and as a freelance science/medical writer. Carolyn graduated summa cum laude from Dartmouth College with a BA in Biology. She has a PhD in Genetics from Harvard University and an MS in Bioethics from Columbia University. She completed a postdoctoral fellowship in medical ethics at NYU Grossman School of Medicine and a Graduate Certificate in Survey Research at UConn’s School of Public Policy.

Cameron Roots

Elibio Rech

Elibio Rech, a molecular engineer, geneticist, Researcher at EMBRAPA, and Director of the National Institute of Science and Technology in Synthetic Biology, developed gene transfer technologies to produce commercial genetically modified plant products. Aim to contribute to the design, construction, and engineering of synthetic genomes, cell-free protein expression, and building cell and synthetic genetic circuits, combining top-down and bottom-up approaches within the synergies and intersections of the recombinant DNA technology for synthetic domestication of specific traits from biodiversity.

Meagan Olsen

Meagan is a PhD student in the Jewett Lab at Northwestern University. Her research focuses on improving cell-free protein synthesis systems in order to rapidly design and manufacture medical therapeutics. She completed her B.S. in chemical engineering at the University of Arkansas. Outside of the lab, Meagan enjoys cooking, reading, and hiking.

Gregory Koblentz

Gregory D. Koblentz is an Associate Professor and Director of the Biodefense Graduate Program at George Mason University’s Schar School of Policy and Government. The Biodefense Graduate Program is a multidisciplinary research and education program designed to prepare students to work on issues at the nexus of health, science, and security. He also directs the Summer Workshop on Pandemics and Global Health Security at the Schar School and is the Editor-in-Chief of The Pandora Report. Dr. Koblentz is a member of the Scientist Working Group on Biological and Chemical Security at the Center for Arms Control and Non-Proliferation in Washington, DC. He serves as a pro bono advisor for the Open Society Justice Initiative and DARPA, as a consultant for the Stimson Center on their cheminformatics program, and is a member of the Biothreat Advisory Board of Heat Biologics. Dr. Koblentz is the author of Strategic Stability in the Second Nuclear Age (Council on Foreign Relations, 2014) and Living Weapons: Biological Warfare and International Security (Cornell University Press, 2009) and co-author of Mapping Maximum Biological Containment Labs Globally (London: King’s College London, May 2021), Editing Biosecurity: Needs and Strategies for Governing Genome Editing (George Mason University and Stanford University, 2018), and Tracking Nuclear Proliferation: A Guide in Maps and Charts (Carnegie Endowment for International Peace, 1998). His research and teaching focus on understanding the causes and consequences of the proliferation of nuclear, biological, and chemical weapons to state and non-state actors and the impact of emerging technologies on international security. He received a PhD in political science from MIT and a MPP from the Harvard Kennedy School.

Nicole Buan

Nicole Buan is an Associate Professor of Biochemistry at the University of Nebraska-Lincoln and has broad expertise in microbial physiology, metabolism, and redox biochemistry. Dr. Buan recently co-founded the Archaea Power Hour virtual seminar series and serves as Associate Editor for Applied Environmental Microbiology and Frontiers in Microbiology (Microbial Physiology and Metabolism) journals. Dr. Buan began research as a high school student in Tucson, Arizona, where she did undergraduate thesis research on ATP-independent molecular chaperone proteins in plants under the supervision of Dr. Elizabeth Vierling at the University of Arizona. She received her PhD from the University of Wisconsin-Madison, where she was a Howard Hughes Predoctoral Fellow in the lab of Jorge Escalante-Semerena. There, she made key contributions to understanding protein:protein interactions involved in coenzyme B12 synthesis in Salmonella, discovered the only known iron-sulfur-cluster-containing B12 adenosyltransferase enzyme, and investigated the use of B12 mimics as chemotherapeutic “Trojan horses”. Her graduate work was recognized by the Department of Bacteriology Herman Smythe Award for Outstanding PhD research. As a NIH Kirschstein Postdoctoral Fellow in the laboratory of William Metcalf at the University of Illinois, Dr. Buan received training in methanogen genetics and characterized the terminal oxidase heterodisulfide reductase enzymes. At Nebraska, Dr. Buan and her students study redox biochemistry, systems, and synthetic biology in archaea, bacteria, and plants on various projects funded by NSF, NIH, USDA, Nebraska Center for Energy Sciences Research, Nebraska Corn Board, and the Water Environment Reuse Foundation. Buan lab research has been awarded two patents, and Dr. Buan is the owner of two biotech startups.

Sarah Carter

Dr. Carter is the Principal at Science Policy Consulting LLC where she focuses on societal and policy implications of emerging biotechnologies, including issues of responsible innovation, biosafety, and biosecurity. She is currently focused on the advanced biotechnologies industry, synthetic biology and DNA sequence screening, and international norms for biosecurity. In recent years, she has worked with several U.S. government agencies as well as industry, academia, and non-profit institutions. Previously, she worked in the Policy Center of the J. Craig Venter Institute and at the White House Office of Science and Technology Policy (OSTP). She is a former AAAS S&T Policy Fellow and a former Mirzayan S&T Fellow of the National Academies. She earned her Ph.D. from the University of California, San Francisco and her bachelor’s degree from Duke University.

Todd Treangen

I am an Assistant Professor in the Computer Science Department at Rice University in Houston, TX. My research group focuses on bioinformatics, specializing in metagenomics, biosecurity, and microbial forensics. In addition, I have prioritized developing open-source bioinformatics software and analysis pipelines designed to facilitate exploratory and hypothesis-driven biological research, aimed at the intersection of microbial ecology, comparative genomics, and computer science. https://www.gitlab.com/treangenlab

John Dileo

John Dileo manages the Biotechnology and Life Sciences Department at the MITRE Corporation in McLean, Virginia. He holds a Ph.D. in Molecular Genetics & Biochemistry from the University of Pittsburgh and has specialized in experimental and theoretical research in molecular, systems, and synthetic biology, while also providing support and oversight to numerous large Government research and development programs in those fields of study. At MITRE, his department has groups that focus on biosafety, security and quality; countering weapons of mass destruction; medical countermeasures development; and human performance optimization.

Becky Mackelprang

Becky Mackelprang is the Director for Security Programs at the Engineering Biology Research Consortium. She leads EBRC’s Security Focus Area, bringing stakeholders across academia, industry, and government together to integrate security awareness into the policy and practice of engineering biology. Becky leads the development of commentary and recommendations on issues such as screening by synthetic DNA providers and the security implications at the intersection of artificial intelligence and engineering biology. She has implemented strategies to incorporate security into researcher education and training. Becky is committed to supporting an engineering biology research and development ecosystem that maximizes societal benefit while using a multi-faceted approach to support safe, secure, and productive innovation. Previously, Becky was an EBRC Science Policy Postdoctoral Scholar, an AAAS Mass Media Fellow, a science communication postdoctoral researcher at UC Berkeley, and received her Ph.D. in Plant Biology from UC Berkeley.

Sam Weiss Evans

Sam’s work focuses on the governance of security concerns and other broader social aspects of emerging research and innovation, especially biology. He is currently a Senior Policy Advisor for the US National Security Commission on Emerging Biotechnology, where he leads the Commission’s work on safety, security, and responsible innovation. Previously, Sam was at Harvard University, in a joint appointment with the School of Government and the School of Engineering and Applied Sciences.

Robert Egbert

Dr. Robert Egbert (Rob) is a staff scientist in the Biological Sciences Division at Pacific Northwest National Laboratory (PNNL). Dr. Egbert is an expert in bacterial genetic circuit design and genome engineering. He received dual-BS degrees in electrical engineering and Korean at Brigham Young University, a PhD in electrical engineering from the University of Washington working with Eric Klavins, and a joint appointment as a postdoctoral researcher at the University of California Berkeley and Lawrence Berkeley National Laboratory with Adam Arkin. He currently leads a DOE program in Secure Biosystems Design on novel genome remodeling approaches to control the persistence of engineered functions in the environment, is Integration Lead for a PNNL-led team for the DARPA Friend or Foe program, and is Co-PI for data-driven synthetic biology within the DARPA Synergistic Discovery and Design program. Dr. Egbert is also the Science Lead for an PNNL internal investment in synthetic biology and biosecurity. Outside of work, Rob loves adventures with his wife and three children: swimming, kayaking, and river rafting in lakes and rivers of the mountain West; backpacking in the Pacific Northwest, Utah red rocks, and Canadian Rocky Mountains; and pinball. Rob also enjoys playing competitive ultimate frisbee.

Jean Peccoud

Dr. Peccoud’s research program focuses on synthetic biology informatics. His group combines computational and experimental efforts to develop predictive models of behaviors encoded in synthetic DNA sequences. He is particularly interested in using methods from synthetic biology to optimize biomanufacturing processes used to produce biologic drugs, antibodies, and other proteins of commercial interest. Peccoud is also actively engaged in efforts to understand the security implications of synthetic biology.

Shortly after completing a graduate research project in molecular immunology, Jean Peccoud’s scientific interests shifted to computational biology. In 1989, he published one of the first articles describing a mathematical model of molecular noise in gene regulatory networks. In 1993, he recognized the importance of real-time PCR and developed new statistical techniques suitable to analyze this new type of data. In 2002, he observed with excitement the very early developments of synthetic biology. After exploring the potential applications of this new technology to plant biotechnology, he blazed a trail in synthetic biology informatics.

Jean Peccoud came to Colorado State University from the Virginia Bioinformatics Institute at Virginia Tech. He brought with him a diverse experience that includes working for Fortune 500 and start-up companies. He is the founding Editor-in-Chief of the journal Synthetic Biology published by Oxford University Press.

Kate Adamala

Kate Adamala is a biochemist building synthetic cells. Her research aims at understanding chemical principles of biology, using artificial cells to create new tools for bioengineering, drug development, and basic research. Kate’s research spans questions from the origin and earliest evolution of life, using synthetic biology to colonize space, to the future of biotechnology and medicine.

Farren Isaacs

Laurie Zoloth

Laurie Zoloth

A leader in the field of religious studies with particular scholarly interest in bioethics and Jewish studies, Laurie Zoloth’s research explores religion and ethics, drawing from sources ranging from Biblical and Talmudic texts to postmodern Jewish philosophy, including the writings of Emmanuel Levinas. Her scholarship spans the ethics of genetic engineering, stem cell research, synthetic biology, social justice in health care, and how science and medicine are taught. She also researches the practices of interreligious dialogue, exploring how religion plays a role in public discussion and policy.

Zoloth is author of Health Care and the Ethics of Encounter: A Jewish Discussion of Social Justice and co-editor of five books, including Notes from a Narrow Ridge: Religion and Bioethics and Jews and Genes: The Genetic Future in Contemporary Jewish Thought.

Zoloth has been the president of the American Academy of Religion and the American Society for Bioethics and Humanities. She was the inaugural director of the Jewish Studies program at San Francisco State University and director of graduate studies in religious studies at Northwestern. She is an elected member of the Hastings Center and a life member of Clare Hall, University of Cambridge. She is a founding board member of the Society for Scriptural Reasoning.

Her work on bioethics and health care led her to serve on the NASA Advisory Council, the space agency’s highest civilian advisory board; the International Planetary Protection Committee; the National Recombinant DNA Advisory Board, and the executive committee of the International Society for Stem Cell Research. She served as chair of the first bioethics advisory board at the Howard Hughes Medical Research Institute and has testified in front of Congress, the President’s Commission on Bioethics, and state legislatures.

Zoloth began her career as a neonatal nurse working in impoverished communities; she holds a bachelor’s degree in women’s studies from the University of California, Berkeley and a bachelor’s degree in nursing from the University of the State of New York. She received a master’s degree in Jewish studies and a doctorate in social ethics from the Graduate Theological Union. Zoloth also holds a master’s degree in English from San Francisco State University.

Prior to joining the University of Chicago, Zoloth served as a Charles McCormick Deering Professor of Teaching Excellence at Northwestern University, holding appointments in the Department of Religious Studies in the Weinberg College of Arts and Sciences and in the Feinberg School of Medicine. At Northwestern, she was founding director of the Brady Program in Ethics and Civic Life at the Weinberg College of Arts and Sciences and founding director of the Center for Bioethics, Science and Society at the Feinberg School of Medicine.

She currently serves on the Ethics Advisory Board of NASA; the steering committee of The Engineering Biology Research Committee; on the CDC (Biological Agents Working Group); and on the Ethics Board of the American Heart Association.

Tae Seok Moon

He has 24 years of research experience in chemistry, systems biology, and synthetic biology, including 5.5 years of industry experience (as of 2021). His research focus (2012-21; 15 grants; $7.3M external funding to him; $16M to the entire team) is understanding gene regulation, evolution, and metabolism, building sensors and genetic circuits, and engineering microbes to solve global problems, including climate crisis, waste valorization, plastic upcycling, sustainability, and health issues. He has published 52 papers, has filed 9 patents, and has given 51 invited and 118 contributed presentations. He has advised 26 PhD/Postdoctoral and 28 undergrad researchers. He is a Founder and Head of the SAB of Moonshot Bio. Several awards include a B&B Wang Award, an NSF CAREER award, an ONR YIP, a Sluder Fellowship (MIT), and the SNU President Prize. He is the Founding Chair of SynBYSS (Synthetic Biology Young Speaker Series) with more than 1000 global audiences.

Twitter handle: @Moon_Synth_Bio

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June Medford

Nathan Hillson

Nathan Hillson

Dr. Hillson earned his Ph.D. in Biophysics from Harvard Medical School. He did his postdoctoral work in Developmental (Micro)Biology at Stanford University School of Medicine. Dr. Hillson's work has spanned the realms of the private (notably as co-founder/Chief Scientific Officer at TeselaGen) and public biotechnology sectors. As Department Head of BioDesign within the Biological Systems & Engineering Division, Dr. Hillson leads scientists and engineers within Lawrence Berkeley National Laboratory whose domain expertise spans synthetic biology, metabolic engineering, microbiology, microbial communities, software engineering, and laboratory automation engineering. As overall Principal Investigator of the U.S. DOE Agile Biofoundry, Dr. Hillson leads scientists/engineers across 8 U.S. DOE National Labs towards the development of a public infrastructure that enables the private sector to reduce the cost and accelerate bioprocess commercialization timelines. This infrastructure complements discovery engines (such as the Joint Genome Institute, to which Dr. Hillson also contributes).

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