Publications – New Releases

Response to NITRD NCO RFI on the Development of an Artificial Intelligence (AI) Action Plan

Publication Date: March 2025

EBRC’s response to OSTP’s Request for Information regarding the development of an Artificial Intelligence (AI) Action Plan to sustain and enhance the US competitive edge within this strategic technology. AI holds a great deal of promise for engineering biology, but it also potentially introduces new risks. Without guardrails and common sense oversight, AI may be appropriated to inform the creation of hazards that could endanger public health and national security. Further, USG must ensure developers and researchers have access to resources required to develop and deploy the technology. Our response recommends policy actions that promote the creation of a competitive and vibrant AI ecosystem that is safe and secure.
See the Request for Information as published in the Federal Register Vol. 90, No. 24 pg 9088.

Keywords: AIxBio, OSTP, AI, ML, LLM, biosecurity, Responsible Innovation, RFI, National AI Strategy

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Response to RFI on NIST AISI’s Draft Document: Managing Misuse Risk for Dual-Use Foundation (AI) Models

Publication Date: March 2025

EBRC’s response to NIST’s Request for Comment regarding their draft document: “Managing Misuse Risk for Dual-Use Foundation Models.” Protecting technologies against potential misuse is critical for both scientific advancement and public safety. We support the updated document and recommend that NIST’s AI Safety Institute continues this work by collaborating with the scientific community to: 1) Better characterize risks specific to specialized chemical and biological design tools; and, 2) Develop targeted mitigation strategies that protect innovation while preventing misuse.

Strengthening a Safe and Secure Nucleic Acid Synthesis Ecosystem

Publication Date: January 2025

This report presents findings, best practices, and recommendations for quality, measurable nucleic acid synthesis screening and was developed by the Engineering Biology Research Consortium (EBRC) in cooperation with the National Institute of Standards and Technology. During 2024, EBRC brought 200 stakeholders together across government, academia, industry, and civil society in a series of workshops to consider key aspects of nucleic acid synthesis screening, including Sequence of Concern database development and conformity assessment. This report provides best practices for a range of stakeholders and offers recommendations to support the adoption of screening practices and improve screening outcomes. Cross-sector collaboration will continue to be necessary to tackle screening challenges and effectively implement U.S. policy. Further, strong international partnerships will be necessary to advance quality screening around the globe (learn more).

Publications – New Releases

Response to NITRD NCO RFI on the Development of an Artificial Intelligence (AI) Action Plan

Response to RFI on NIST AISI’s Draft Document: Managing Misuse Risk for Dual-Use Foundation (AI) Models

Strengthening a Safe and Secure Nucleic Acid Synthesis Ecosystem

Safety Considerations for Chemical and/or Biological AI Models

Publication Date: December 2024

An EBRC response to NIST RFI 89 FR 80886: Safety Considerations for Chemical or Biological AI Models.

Publications – New Releases

Response to NITRD NCO RFI on the Development of an Artificial Intelligence (AI) Action Plan

Response to RFI on NIST AISI’s Draft Document: Managing Misuse Risk for Dual-Use Foundation (AI) Models

Strengthening a Safe and Secure Nucleic Acid Synthesis Ecosystem

Safety Considerations for Chemical and/or Biological AI Models

Publication Date: December 2024 An EBRC response to NIST RFI 89 FR 80886: Safety Considerations for Chemical or Biological AI Models.

Publication Date: December 2024

An EBRC response to NIST RFI 89 FR 80886: Safety Considerations for Chemical or Biological AI Models.