Resources

  • Research Associate

    Inscripta was founded in 2015 and recently launched the world’s first benchtop Digital Genome Engineering platform. The company is growing aggressively, investing in its leadership, team, and technology with a recent $150mm financing round led by Fidelity and TRowe price. The company’s advanced CRISPR-based platform, consisting of an instrument, reagents, and software, offers a fully automated workflow that enables multiplexed, trackable editing of cells at an unprecedented scale. Inscripta’s mission is to enable scientists to realize the full potential of biology. Due to rapid growth and recent commercialization, Inscripta has an opening for a Systems Integration Research Associate located in Boulder, CO.

    Summary
    We are looking for an outstanding Research Associate to support and drive CRISPR-based DNA editing projects. This individual will innovate in areas of assay development, process optimization, and product automation. Essential aspects of this position include: following established protocols, troubleshooting, innovative solutions, design and execution of informative experiments, and superior data analysis. The right candidate will enthusiastically leverage their creativity, and research experience to build an industry-leading genetic-engineering platform in a highly innovative, team-oriented, fast-paced R&D environment.

    Responsibilities
    • Provide scientific support in a technical team that is building a high-throughput genetic-engineering platform.
    • Execute complex, highly multiplexed experiments.
    • Perform microbiology and molecular biology techniques: culturing microorganisms, PCR, genetic-engineering, and robotic liquid handling.
    • Conduct detailed data analysis and provide recommendations based on technical results.
    • Maintain detailed experimental records.
    • Present clear and concise written and oral communications to colleagues and supervisors.

    Requirements
    • Direct experience with microbiology and molecular biology techniques such as: culturing microorganisms, PCR, qPCR, nucleic acid purification, and genome editing.
    • Demonstrated record of innovation in molecular or cellular biology preferred.
    • Experience converting prototype devices into fully automated modules and instruments.
    • Familiarity with next generation sequencing, sequencing library preparation, and other genomic platforms.
    • Desire to work in a team environment and collaborate closely with other cross-functional and geographically distributed teams.
    • Ability to learn quickly in a fast-paced startup environment.
    • BS in molecular biology, bioengineering, or a related discipline.

    Inscripta offers a competitive base salary, bonus plan, benefits package, 401k match, and an attractive equity program to all team members. Starting Salary Range: $50,000 – $60,000 per year. This salary range is provided per current averages and expectations. The salary and job title for this opening will be based on the selected candidate’s qualifications and experience and may be outside this range. Join us and work with a cutting edge organization creating cutting edge technology. At Inscripta, we don’t just accept difference — we celebrate it, support it, and thrive on it for the benefit of our employees, our innovation, and our community. We are proud to be an equal opportunity workplace because the more inclusive we are as a company, the better our work will be. Inscripta is headquartered in Boulder, CO with offices in Pleasanton and San Diego, CA. This position is located in our Boulder, CO office location but may require travel to our Pleasanton, CA office as needed.

  • Engineering Technician

    Inscripta is developing the world’s first scalable platform for benchtop Digital Genome Engineering. The company’s advanced CRISPR-based platform, consisting of an instrument, reagents, and software, will offer a fully automated workflow that enables multiplexed, trackable editing of cells at an unprecedented scale. Inscripta’s goal is to empower scientists whose gene editing research is stifled by current technical and licensing limitations. By providing this unique platform and engaging in collaborative business practices, such as making its MAD7 CRISPR nuclease free for research purposes, the company enables scientists to realize a new era of biological discovery. Due to rapid growth Inscripta has an opening for an Engineering Technician located in Pleasanton, CA.

    Summary:
    We are looking for an experienced Engineering Technician who will significantly contribute to the development of our Digital Genome Engineering platforms. You will work with an extremely talented team who are used to moving quickly. This is an exciting opportunity to build the technology from the ground up.

    Responsibilities:
    • Build, service, and test electro-mechanical fluidic systems designed by Inscripta engineers.
    • Work with engineering team to execute test plans on instrument, collect data, perform analysis, and report and present the results.
    • Maintain accurate and complete data records in electronic form.
    • Assist root cause analysis on issues found during testing.
    • Design and execute mechanical, electrical, and full system tests on existing and newly developed systems.
    • Communicate effectively with a cross-functional team consisting of engineers and scientists.

    Requirements:
    • 3-5+ years of experience building & testing electro-mechanical equipment.
    • Programming experience: NET, C++, python or similar.
    • Mechanically minded individuals to identify and accurately report problems.
    • Strong debugging, troubleshooting, and root-cause analysis skills.
    • Organized and can keep track of assigned tasks and priorities, with minimal supervision.
    • Skilled with computers and Microsoft Office; especially Excel, windows filing system, and others.
    • Strong communication skills (verbal and written).
    • AS or BS engineering degree.
    • Experience using hand tools and multimeter.

    Bonus Qualifications:
    • Ability to read, revise, and make engineering drawings and electrical schematics.
    • 3D CAD experience (Solidworks).
    • Electronics design experience.
    • Mechanical fabrication experience.
    • Experience in a startup setting.

    Inscripta offers a competitive base salary, bonus plan, benefits package, 401k match, and an attractive equity program to all team members. Join us and work with a cutting edge organization creating cutting edge technology. At Inscripta, we don’t just accept difference — we celebrate it, support it, and thrive on it for the benefit of our employees, our innovation, and our community. We are proud to be an equal opportunity workplace because the more inclusive we are as a company, the better our work will be. Inscripta is headquartered in Boulder, CO with offices in Pleasanton and San Diego, CA. This position is located in our Pleasanton office location.

  • Field Applications Scientist – North America East

    Inscripta was founded in 2015 and recently launched the world’s first benchtop Digital Genome Engineering platform. The company is growing aggressively, investing in its leadership, team, and technology with a recent $150mm financing round led by Fidelity and TRowe price. The company’s advanced CRISPR-based platform, consisting of an instrument, reagents, and software, offers a fully automated workflow that enables multiplexed, trackable editing of cells at an unprecedented scale. Inscripta’s mission is to enable scientists to realize the full potential of biology. Due to rapid growth and recent commercialization, Inscripta has an opening for a Field Applications Scientist (FAS), North America East. This role can be based in or around any East Coast city near a major airport.

    We are looking for outstanding Field Applications Scientist to drive market adoption and ensure customer success using Inscripta’s Digital Genome Engineering platform. This individual will provide premier support for our instrumentation, consumables, software and assays. The FAS will leverage their experience in genome editing, next generation sequencing and NGS data analysis to match customer research goals to our platform’s capabilities, conduct training, project design and troubleshooting, and help drive the reorder cycle. They’ll also relay customer feedback to Field Sales, Applications, and Marketing to optimize the customer’s user experience.

    Responsibilities
    • Deliver exceptional pre/post-sales applications support; educate customers on the use of our technology and help them conduct novel genome engineering projects to maximize their research success.
    • Understand the customer’s research requirements to help them design, implement, analyze and interpret their experiments, thus building the scientific credibility of both the FAS and our technology.
    • Work with Field Sales representatives, supporting their efforts to identify, develop and close high-value sales opportunities to meet/exceed revenue targets for hardware and consumables.
    • Persuasively deliver technical, customer-facing seminars covering a variety of scientific research areas, applications, products and data related to Inscripta’s technology platform.
    • Coordinate with Sales, Applications Development, Marketing and Product Management to implement successful strategies that balance the needs of the customer, Sales, and internal departments.
    • Act as an internal customer advocate by communicating information between the customer, Sales, Marketing, Applications and other departments related to product feedback, competitive intelligence, market trends, and effectiveness of marketing, positioning, and field tactics.
    • Build, engage and leverage a network of early access and KOL customers to drive the awareness and reputation of our platform and deepen customer relationships with key scientific leaders.

    Requirements
    • Research and/or commercial experience in one or more of the following areas: CRISPR-based genome editing, next generation sequencing, synthetic biology, metabolic engineering and functional genomics.
    • Familiarity with/expertise using CRISPR design tools and/or next generation sequence analysis software.
    • Experience in the demonstration, installation, operation and troubleshooting of sophisticated, high-throughput instrument platforms. Previous field applications support experience is preferred.
    • Ph.D. in a relevant field with 2+ years’ experience (post-doc or industrial); Master’s degree with 5+ years’ experience and exceptional qualifications.
    • Experience in successful experimental design, interpretation, troubleshooting and optimization. Ability to develop solutions to complex problems that require innovation and collaboration.
    • Strong verbal, written and interpersonal communication skills to effectively deliver technical presentations, handle customer issues and work collaboratively to support the efforts of Field Sales.
    • Ability to learn quickly and work in a highly innovative, fast-paced startup environment, collaborating closely with other cross-functional and geographically distributed teams.
    • Avg. 30-40% overnight travel primarily in the eastern half of North America. This position will be based in or around any East Coast city near a major airport.

    Inscripta offers a competitive base salary, bonus plan, benefits package, 401k match and an attractive equity program to all team members. Join us and work with a cutting edge organization creating cutting edge technology. At Inscripta, we don’t just accept difference — we celebrate it, support it, and thrive on it for the benefit of our employees, our innovation, and our community. We are proud to be an equal opportunity workplace because the more inclusive we are as a company, the better our work will be. Inscripta is headquartered in Boulder, CO with offices in Pleasanton and San Diego, CA. This position can be based in or around any East Coast city near a major airport.

  • Senior Scientist

    Inscripta was founded in 2015 and recently launched the world’s first benchtop Digital Genome Engineering platform. The company is growing aggressively, investing in its leadership, team, and technology with a recent $150mm financing round led by Fidelity and TRowe price. The company’s advanced CRISPR-based platform, consisting of an instrument, reagents, and software, offers a fully automated workflow that enables multiplexed, trackable editing of cells at an unprecedented scale. Inscripta’s mission is to enable scientists to realize the full potential of biology. Due to rapid growth and recent commercialization, Inscripta has an opening for a Senior Scientist located in our Pleasanton, CA office.

    Summary
    Do you love tinkering with nucleic acids? Is protocol improvement an unshakeable habit? We are looking for a creative scientist who is passionate about building and commercializing the assays that drive CRISPR-based genome editing at Inscripta.

    Essential aspects of this position include: prolific innovation, superior experimental design & execution, and robust protocol development. The right candidate will enthusiastically leverage their experience, curiosity, and creativity to build industry-leading molecular biology and genetic-engineering tools in a highly innovative, team-oriented, and vibrant R&D environment.

    Responsibilities
    • Design and develop robust assays with simple, automation-compatible workflows.
    • Work collaboratively with biochemists, molecular biologists, bioinformaticians, and engineers to identify, build, and optimize the assays that propel genome engineering.
    • Execute complex, highly multiplexed experiments that accurately evaluate protocol improvements.
    • Conduct detailed data analyses, use bioinformatic pipelines, & provide data-driven recommendations.
    • Transfer new methodologies and assays from R&D to Systems-Integration and Manufacturing.
    • Provide clear and concise written and oral communications to colleagues and supervisors.

    Required Skills and Experience
    • Extensive experience with: NGS, PCR, qPCR, oligo design, and nucleic acid manipulation.
    • Demonstrated record of innovation developing molecular biology assays and techniques.
    • Proven ability to work collaboratively on cross-functional teams in a highly matrixed environment.
    • Exceptional data analysis skills combined with strong logical thinking.
    • Ability to learn quickly and willingness to work determinedly at a dynamic startup company.

    Desired Skills and Experience
    • Familiarity with at least one programming or scripting language such as R or Python.
    • Experience with genome engineering, cloning, and microbe & mammalian cell culture.

    Inscripta offers a competitive base salary, bonus plan, benefits package, 401k match and an attractive equity program to all team members. Join us and work with a cutting edge organization creating cutting edge technology. At Inscripta, we don’t just accept difference — we celebrate it, support it, and thrive on it for the benefit of our employees, our innovation, and our community. We are proud to be an equal opportunity workplace because the more inclusive we are as a company, the better our work will be. Inscripta is headquartered in Boulder, CO with offices in Pleasanton and San Diego, CA. This position is located in our Pleasanton, CA office location.

  • Director/ Senior Director, Mammalian Cell Biology

    Inscripta was founded in 2015 and recently launched the world’s first benchtop Digital Genome Engineering platform. The company is growing aggressively, investing in its leadership, team, and technology with a recent $150mm financing round led by Fidelity and TRowe price. The company’s advanced CRISPR-based platform, consisting of an instrument, reagents, and software, offers a fully automated workflow that enables multiplexed, trackable editing of cells at an unprecedented scale. Inscripta’s mission is to enable scientists to realize the full potential of biology. Due to rapid growth and recent commercialization, Inscripta has an opening for a Director/Sr. Director, Mammalian Cell Biology, located in Boulder, CO or Pleasanton, CA.

    Summary:
    Inscripta is looking for an experienced scientific and team leader for our Mammalian Cell Biology group to achieve innovative product development of Inscripta’s genome engineering reagents and platforms.

    Responsibilities:
    • Conceive, propose, prioritize, and drive scientific strategies around innovative cell biological approaches to develop and deliver CRISPR-based reagent technologies that support Inscripta’s gene editing products.
    • Direct and mentor a team of 10-15 cell biological scientists and research associates designing, screening and optimizing genome editing reagents for successful product integration.
    • Provide vision and structure to the organization and operation of a high-functioning team in a matrixed, product development environment focused on delivering high quality results in accordance with requirements across multiple projects and products.
    • Provide teaching / training and implement rigorous and robust experimental design and quality control metrics to support generation of the highest degree of quality and reproducible data.
    • Direct cross-functional projects across computational science, biology, chemistry, and engineers in a matrixed product development environment.
    • Provide subject matter expertise on existing and developing genome editing science and technologies, as well as screening and measurement methodologies, with a goal of consistently driving innovation and improvements to Inscripta’s genome editing chemistries and platforms.
    • As opportunities arise internally, take on a role as core team member to achieve product development objectives in a matrixed environment, in accordance with corporate goals.
    • Work with core team and senior leadership to ensure goals are aligned with strategic direction.

    Requirements:
    • Ph.D. in genetics, cell biology or related scientific field and approximately 7 to 10 years of relevant industry experience, including 3-5 years’ experience leading and mentoring teams of 5 or more scientists and research associates; strong preference for experience in start-up organizations.
    If this seems like your dream job, but you’re not sure if you qualify, please apply anyway!
    • Track record of innovation and scientific creativity in developing solutions for genome engineering reagent system and integrated performance requirements in life sciences / biotechnology industry.
    • Experience successfully managing complex projects and adjusting to changing priorities in a product development environment, including developing and executing focused project plans.
    • Openness and capability to “lead from the bench” when required.
    • Maturity and accountability to lead and deliver on commitments in a matrixed organization.
    • Ability to serve as subject matter expert within the fields of DNA repair, gene editing, genetics, cell biology, and ideally, NGS and related genome editing read out technologies.
    • Experience positioning projects and individual contributors for success through team member goal setting, continual assessment, feedback and coaching, as well as technical direction and task prioritization.
    • Ability to organize, communicate, and present complex technical data, progress and challenges to cross-disciplinary teams, senior management and key stakeholders.
    • Outstanding interpersonal, scientific leadership and collaboration skills, including self-awareness and ability to manage complex dynamics.

    Inscripta offers a competitive base salary, bonus plan, benefits package, 401k match and an attractive equity program to all team members. Join us and work with a cutting edge organization creating cutting edge technology. At Inscripta, we don’t just accept difference — we celebrate it, support it, and thrive on it for the benefit of our employees, our innovation, and our community. We are proud to be an equal opportunity workplace because the more inclusive we are as a company, the better our work will be. Inscripta is headquartered in Boulder, CO with offices in Pleasanton and San Diego, CA. The role can work out of either location, but Pleasanton workers will travel regularly to Boulder, CO.

  • Scientist

    Inscripta was founded in 2015 and recently launched the world’s first benchtop Digital Genome Engineering platform. The company is growing aggressively, investing in its leadership, team, and technology with a recent $150mm financing round led by Fidelity and TRowe price. The company’s advanced CRISPR-based platform, consisting of an instrument, reagents, and software, offers a fully automated workflow that enables multiplexed, trackable editing of cells at an unprecedented scale. Inscripta’s mission is to enable scientists to realize the full potential of biology. Due to rapid growth and recent commercialization, Inscripta has an opening for a Scientist located in Pleasanton, CA.

    Summary
    Inscripta is searching for a Scientist with expertise in mammalian cell management to join our product development team. The ideal candidate will have deep technical knowledge and hands on experience in the culturing, characterization, and manipulation of mammalian cells. In this role, they will work on a multi-disciplinary team to assess reagent and system performance of Inscripta’s digital genome engineering platforms, as well as be responsible for implementing methods to QC cell viability, health and other characteristics critical for the compatibility of our technology with customer applications. They will also thrive in a data-driven environment and work closely with a world class team of life scientists, engineers, and computational data scientists.

    Responsibilities
    • Independently design, execute, and analyze experiments to assess performance of product-facing reagent chemistry.
    • Optimize and deploy protocols for mammalian cell-based workflows.
    • Develop assays to QC cell viability, health, and other critical product relevant cell characteristics.
    • Implement and maintain human cell culture, characterization, and banking standards.
    • Maintain policies and procedures related to biosafety.
    • Effectively direct, organize, and manage workload to execute complex experiments according to an aggressive product development schedule.
    • Present clear and concise written and oral communications to colleagues and supervisors, participate in technical meetings, and provide recommendations based on technical results.

    Requirements
    • Ph.D in cell biology, immunology, biochemistry, developmental biology, molecular biology, or a related discipline.
    • Demonstrated experience in the derivation, culture, and characterization of mammalian cells. Particular consideration will be given to candidates with demonstrated experience working with primary cells (e.g. human immune cells, human pluripotent stem cells, keratinocytes, hepatocytes, and/or neurons).
    • Experience developing assays to characterize human cells, including multicolor flow cytometry and qPCR.
    • Ability to work both independently, within matrixed project teams, and in a dynamic environment where priorities can shift with data-driven decisions.
    • Excellent written and oral communication skills.
    • Track record of attention to detail and focus on standardization.

    Inscripta offers a competitive base salary, bonus plan, benefits package, 401k match and an attractive equity program to all team members. Base Salary Range: $90,000 to $100,000 per year. Base salary range provided per current averages and expectations. The salary and job title for this opening will be based on the selected candidate’s qualifications and experience and may be outside this range. Join us and work with a cutting edge organization creating cutting edge technology. At Inscripta we don’t just accept difference — we celebrate it, support it, and thrive on it for the benefit of our employees, our innovation, and our community. We are proud to be an equal opportunity workplace because the more inclusive we are as a company, the better our work will be. Inscripta is headquartered in Boulder, CO with offices in Pleasanton and San Diego, CA. This position is located in our Pleasanton office location.

  • Staff Scientist/ Senior Scientist

    Inscripta was founded in 2015 and recently launched the world’s first benchtop Digital Genome Engineering platform. The company is growing aggressively, investing in its leadership, team, and technology with a recent $150mm financing round led by Fidelity and TRowe price. The company’s advanced CRISPR-based platform, consisting of an instrument, reagents, and software, offers a fully automated workflow that enables multiplexed, trackable editing of cells at an unprecedented scale. Inscripta’s mission is to enable scientists to realize the full potential of biology. Due to rapid growth and recent commercialization, Inscripta has an opening for a Staff/Senior Scientist located in Pleasanton, CA.

    Summary
    Inscripta is searching for a highly talented Staff/Senior Scientist to join our Biochemistry group. The ideal candidate will have demonstrated experience in assay development, a strong analytical background in biochemistry, proficiency with a variety of molecular read-out tools, and the ability to design & execute complex experiments according to a project schedule. In this role, they will be a key member of our multi-disciplinary team and lead efforts to stand up assays to quantitatively assess system performance of Inscripta’s mammalian digital genome engineering platform. They will also thrive in a data-driven, dynamic environment and work closely with a world class team of life scientists, engineers, and computational data scientists.

    Responsibilities
    • Lead the design and development of custom assays aimed at reagent and edit detection.
    • Lead the design and verification of custom assays to quantify the presence, function, and/or kinetics of biomolecules and complexes formed from them (e.g. protein/DNA complexes), in vivo or ex vivo, to enable metrics-driven read-outs of system performance.
    • Leverage both computational and empirical methods for experiment design and data analysis.
    • Verify assay performance using statistically rigorous experimental design with appropriate selection of sample preparation and measurement controls to establish assay sensitivity and precision.
    • Collaborate with life scientists, engineers and computational data scientists to define and develop measurement tool specifications, metrics and data analysis methods.
    • Effectively direct, organize, and manage workload to execute complex experiments according to an aggressive product development schedule.
    • Present clear and concise written and oral communications to colleagues and supervisors, participate in technical meetings, and provide recommendations based on technical results.

    Requirements
    • Ph.D. in Biochemistry, Molecular Biology, Chemistry, or a related discipline
    • A minimum of 2 years of experience developing robust biochemical, biophysical, and/or biomolecular assays. For the Staff Scientist level, candidates would need to have at least six years of relevant experience. Salary will be based on experience.
    • Proficiency in a breadth of biochemistry/molecular biology techniques – including DNA/RNA purification, protein purification, ddPCR/qPCR, RT-qPCR, Sanger/NGS sequencing, primer/probe design, and protein labeling techniques (e.g. immunohistochemistry).
    • Ability to work both independently, within matrixed project teams, and in a dynamic environment where priorities can shift with data-driven decisions.
    • Excellent written and oral communication skills.
    • Exceptional data analysis skills combined with strong analytical thinking.
    • Track record of creativity and problem-solving.

    Inscripta offers a competitive base salary, bonus plan, benefits package, 401k match and an attractive equity program to all team members. Base Salary Range: $110,000 to $150,000 per year. Base salary range provided per current averages and expectations. The salary and job title for this opening will be based on the selected candidate’s qualifications and experience and may be outside this range. Join us and work with a cutting edge organization creating cutting edge technology. At Inscripta, we don’t just accept difference — we celebrate it, support it, and thrive on it for the benefit of our employees, our innovation, and our community. We are proud to be an equal opportunity workplace because the more inclusive we are as a company, the better our work will be. Inscripta is headquartered in Boulder, CO with offices in Pleasanton and San Diego, CA. This position is located in our Pleasanton office location.

  • Staff Systems Engineer/ Senior Staff Systems Engineer

    Inscripta was founded in 2015 and recently launched the world’s first benchtop Digital Genome Engineering platform. The company is growing aggressively, investing in its leadership, team, and technology with a recent $150mm financing round led by Fidelity and T. Rowe Price. The company’s advanced CRISPR-based platform, consisting of an instrument, reagents, and software, offers a fully automated workflow that enables multiplexed, trackable editing of cells at an unprecedented scale. Inscripta’s mission is to enable scientists to realize the full potential of biology. Due to rapid growth and recent commercialization, Inscripta has an opening for a Staff Systems Engineer /Sr. Staff Systems Engineer located in Pleasanton, CA or Boulder, CO.

    Summary:
    The Staff Systems Engineer /Sr. Staff Systems Engineer who will use a multi-disciplinary approach to define architecture and sub-system requirements for a new, industry leading gene editing platform. These disciplines include biology, reagents, and instrument consumables as well as the associated software and hardware. This is an opportunity to drive the definition and implementation of system engineering best practices.

    Responsibilities:
    • Provide project level leadership and work with SMEs to define, design, develop, characterize, and validate platforms at the interface of electromechanical systems and biology.
    • Analyze, design and test biological systems that include fluidics, optics, sensors, machined and molded hardware and consumable hardware components.
    • Collaborate with a diverse cross-functional team (biologists, analytical scientists, engineers, etc.) to define and develop robust integrated instrumentation, consumables and software.
    • Proactive development of in-depth knowledge of the product technology and a good working knowledge of the associated biological processes.
    • Model fluid flows, biological flows, temperatures, reagent concentrations, etc. to construct a complete system model, especially to spec submodule interfaces and to identify critical parameters and determine best design approach.
    • Model interfaces between instrument submodules across hardware, software, and consumables to identify critical parameters and determine best design approach.
    • Design and perform tests to ensure specifications are met; collect data to help troubleshoot and evolve designs.

    Requirements:
    • B.S., M.S., or PhD in Systems, Mechanical, or Electrical Engineering or related engineering discipline.
    • 7+ years of system design experience. Taken at least one commercial instrument from concept to shipment.
    • Experience with life science instrumentation.
    • Strong interdepartmental communication skills.

    Desired:
    • Taken commercial instrument(s) involving biology or biochemistry from concept to shipment.
    • Experience in instrumentation and consumables development.
    • Experience with engineering documentation and control practices.
    • Proven history of systematic troubleshooting and innovative problem solving.
    • Experience with aseptic biological reagent and cell handling methodologies and design of engineering systems to support them (e.g., aseptic fittings and sterile equipment design).
    • Experience with systems modeling (Matlab, COMSOL, or similar).
    • Experience with requirements analysis, FMEA, reliability and compliance testing.
    • Understanding of statistical methods and Design of Experiments.

    Inscripta offers a competitive base salary, bonus plan, benefits package, 401k match and an attractive equity program to all team members. Base Salary Range: $150k – $200k per year. Base salary range provided per current averages and expectations. The salary and job title for this opening will be based on the selected candidate’s qualifications and experience and may be outside this range. Join us and work with a cutting edge organization creating cutting edge technology. At Inscripta, we don’t just accept difference — we celebrate it, support it, and thrive on it for the benefit of our employees, our innovation, and our community. We are proud to be an equal opportunity workplace because the more inclusive we are as a company, the better our work will be. Inscripta is headquartered in Boulder, CO with offices in Pleasanton and San Diego, CA. This position can be at either our Boulder or Pleasanton location.

  • Field Applications Scientist – North America West

    Inscripta was founded in 2015 and recently launched the world’s first benchtop Digital Genome Engineering platform. The company is growing aggressively, investing in its leadership, team, and technology with a recent $150mm financing round led by Fidelity and TRowe price. The company’s advanced CRISPR-based platform, consisting of an instrument, reagents, and software, offers a fully automated workflow that enables multiplexed, trackable editing of cells at an unprecedented scale. Inscripta’s mission is to enable scientists to realize the full potential of biology. Due to rapid growth and recent commercialization, Inscripta has an opening for a Field Applications Scientist (FAS), North America West. This role can be based in or around the San Francisco area or any West Coast city near a major airport.

    We are looking for outstanding Field Applications Scientist to drive market adoption and ensure customer success using Inscripta’s Digital Genome Engineering platform. This individual will provide premier support for our instrumentation, consumables, software and assays. The FAS will leverage their experience in genome editing, next generation sequencing and NGS data analysis to match customer research goals to our platform’s capabilities, conduct training, project design and troubleshooting, and help drive the reorder cycle. They’ll also relay customer feedback to Field Sales, Applications, and Marketing to optimize the customer’s user experience.

    Responsibilities:
    • Deliver exceptional pre/post-sales applications support; educate customers on the use of our technology and help them conduct novel genome engineering projects to maximize their research success.
    • Understand the customer’s research requirements to help them design, implement, analyze and interpret their experiments, thus building the scientific credibility of both the FAS and our technology.
    • Work with Field Sales representatives, supporting their efforts to identify, develop and close high-value sales opportunities to meet/exceed revenue targets for hardware and consumables.
    • Persuasively deliver technical, customer-facing seminars covering a variety of scientific research areas, applications, products and data related to Inscripta’s technology platform.
    • Coordinate with Sales, Applications Development, Marketing and Product Management to implement successful strategies that balance the needs of the customer, Sales, and internal departments.
    • Act as an internal customer advocate by communicating information between the customer, Sales, Marketing, Applications and other departments related to product feedback, competitive intelligence, market trends, and effectiveness of marketing, positioning, and field tactics.
    • Build, engage and leverage a network of early access and KOL customers to drive the awareness and reputation of our platform and deepen customer relationships with key scientific leaders.

    Requirements:
    • Research and/or commercial experience in one or more of the following areas: CRISPR-based genome editing, next generation sequencing, synthetic biology, metabolic engineering and functional genomics.
    • Familiarity with/expertise using CRISPR design tools and/or next generation sequence analysis software.
    • Experience in the demonstration, installation, operation and troubleshooting of sophisticated, high-throughput instrument platforms. Previous field applications support experience is preferred.
    • Ph.D. in a relevant field with 2+ years’ experience (post-doc or industrial); Master’s degree with 5+ years’ experience and exceptional qualifications.
    • Experience in successful experimental design, interpretation, troubleshooting and optimization. Ability to develop solutions to complex problems that require innovation and collaboration.
    • Strong verbal, written and interpersonal communication skills to effectively deliver technical presentations, handle customer issues and work collaboratively to support the efforts of Field Sales.
    • Ability to learn quickly and work in a highly innovative, fast-paced startup environment, collaborating closely with other cross-functional and geographically distributed teams.
    • Avg. 30-40% overnight travel in the Western half of North America. This position will be based in or around the San Francisco area or any West Coast city near a major airport.

    Inscripta offers a competitive base salary, bonus plan, benefits package, 401k match and an attractive equity program to all team members. Join us and work with a cutting edge organization creating cutting edge technology. At Inscripta, we don’t just accept difference — we celebrate it, support it, and thrive on it for the benefit of our employees, our innovation, and our community. We are proud to be an equal opportunity workplace because the more inclusive we are as a company, the better our work will be. Inscripta is headquartered in Boulder, CO with offices in Pleasanton and San Diego, CA. This position can be based in or around the San Francisco area or any West Coast city near a major airport.

  • Scientific Project Manager

    Inscripta was founded in 2015 and recently launched the world’s first benchtop Digital Genome Engineering platform. The company is growing aggressively, investing in its leadership, team, and technology with a recent $150mm financing round led by Fidelity and T. Rowe Price. The company’s advanced CRISPR-based platform, consisting of an instrument, reagents, and software, offers a fully automated workflow that enables multiplexed, trackable editing of cells at an unprecedented scale. Inscripta’s mission is to enable scientists to realize the full potential of biology. Due to rapid growth and recent commercialization, Inscripta has an opening for a Scientific Project Manager located in Boulder, CO, Pleasanton, CA, or San Diego, CA.

    Summary:
    We are looking for a self-driven and talented candidate to join our Program Management team to work with cross-functional, technical teams developing new products. Partnering closely with the project lead, this individual will make sure that priorities, risks, resources, and schedules are established, managed, and reported across the project.

    Responsibilities:
    • Serve as project manager for the development of instruments and consumables at the interface of biology, biochemistry, fluidic, electrical, and mechanical disciplines.
    • With the technical lead of the project, help define and prioritize the team towards retiring technical risks and project goals.
    • Work across commercial teams, technical teams, and executives to manage the project portfolio.
    • Develop and track project plans, schedules, and risks across a multidisciplinary team and diversity of stakeholders.
    • Identify and resolve issues with interdependent timelines, priorities, and resourcing.
    • Present project and platform progress updates to leadership teams against project expectations.
    • Drive improvements in Inscripta’s product development processes and practices to meet company needs.

    Requirements:
    • BS, MS, or PhD in biology, biochemistry, chemistry, genetics, or engineering.
    • At least 6 years of experience in development of new instruments or consumables/reagents products in biotech or life sciences.
    • At least 2 years in a project management role is required. PMP certification desired.
    • Demonstrated abilities to organize, plan, prioritize, and track complex, multidisciplinary development projects required.
    • Strong interdepartmental communication skills (oral, listening, written, presentation) are required
    • Ability to be adaptable in a fast-paced environment.
    • Experience taking at least 1 platform product combining electromechanical instrumentation, fluidics, and software through a product development process (concept through full-scale operation) desired.

    Inscripta offers a competitive base salary, bonus plan, benefits package, 401k match and an attractive equity program to all team members. Join us and work with a cutting edge organization creating cutting edge technology. At Inscripta, we don’t just accept difference — we celebrate it, support it, and thrive on it for the benefit of our employees, our innovation, and our community. We are proud to be an equal opportunity workplace because the more inclusive we are as a company, the better our work will be. Inscripta is headquartered in Boulder, CO with offices in Pleasanton and San Diego, CA. This position is located in our Boulder, CO, Pleasanton, CA, or San Diego, CA location.

  • Director/ Senior Director, Mammalian Cell Biology

    Inscripta was founded in 2015 and recently launched the world’s first benchtop Digital Genome Engineering platform. The company is growing aggressively, investing in its leadership, team, and technology with a recent $150mm financing round led by Fidelity and TRowe price. The company’s advanced CRISPR-based platform, consisting of an instrument, reagents, and software, offers a fully automated workflow that enables multiplexed, trackable editing of cells at an unprecedented scale. Inscripta’s mission is to enable scientists to realize the full potential of biology. Due to rapid growth and recent commercialization, Inscripta has an opening for a Director/Sr. Director, Mammalian Cell Biology, located in Boulder, CO or Pleasanton, CA.

    Inscripta is looking for an experienced scientific and team leader for our Mammalian Cell Biology group to achieve innovative product development of Inscripta’s genome engineering reagents and platforms.

    Responsibilities:
    • Conceive, propose, prioritize, and drive scientific strategies around innovative cell biological approaches to develop and deliver CRISPR-based reagent technologies that support Inscripta’s gene editing products.
    • Direct and mentor a team of 10-15 cell biological scientists and research associates designing, screening and optimizing genome editing reagents for successful product integration.
    • Provide vision and structure to the organization and operation of a high-functioning team in a matrixed, product development environment focused on delivering high quality results in accordance with requirements across multiple projects and products.
    • Provide teaching / training and implement rigorous and robust experimental design and quality control metrics to support generation of the highest degree of quality and reproducible data.
    • Direct cross-functional projects across computational science, biology, chemistry, and engineers in a matrixed product development environment.
    • Provide subject matter expertise on existing and developing genome editing science and technologies, as well as screening and measurement methodologies, with a goal of consistently driving innovation and improvements to Inscripta’s genome editing chemistries and platforms.
    • As opportunities arise internally, take on a role as core team member to achieve product development objectives in a matrixed environment, in accordance with corporate goals.
    • Work with core team and senior leadership to ensure goals are aligned with strategic direction.

    Requirements:
    • Ph.D. in genetics, cell biology or related scientific field and at least 10 years of relevant industry experience with 5+ years’ experience leading and mentoring teams of 5 or more scientists and research associates; strong preference for experience in start-up organizations.
    • Track record of innovation and scientific creativity in developing solutions for genome engineering reagent system and integrated performance requirements in life sciences / biotechnology industry.
    • Experience successfully managing complex projects and adjusting to changing priorities in a product development environment, including developing and executing focused project plans.
    • Openness and capability to “lead from the bench” when required.
    • Maturity and accountability to lead and deliver on commitments in a matrixed organization.
    • Ability to serve as subject matter expert within the fields of DNA repair, gene editing, genetics, cell biology, and ideally, NGS and related genome editing read out technologies.
    • Experience positioning projects and individual contributors for success through team member goal setting, continual assessment, feedback and coaching, as well as technical direction and task prioritization.
    • Ability to organize, communicate, and present complex technical data, progress and challenges to cross-disciplinary teams, senior management and key stakeholders.
    • Outstanding interpersonal, scientific leadership and collaboration skills, including self-awareness and ability to manage complex dynamics.

    Inscripta offers a competitive base salary, bonus plan, benefits package, 401k match, and an attractive equity program to all team members. Join us and work with a cutting edge organization creating cutting edge technology. At Inscripta we don’t just accept difference — we celebrate it, support it, and thrive on it for the benefit of our employees, our innovation, and our community. We are proud to be an equal opportunity workplace because the more inclusive we are as a company, the better our work will be. Inscripta is headquartered in Boulder, CO with offices in Pleasanton and San Diego, CA. The role can work out of either our Pleasanton, CA or Boulder, CO, but Pleasanton workers will travel regularly to Boulder, CO.

  • Synthetic Biology Scientist

    ResVita Bio is an early-stage synthetic biology start-up spun out of UC Berkeley. We seek to build genetically engineered skin probiotics to treat chronic skin diseases. We have developed a platform for controlled colonization of the skin with engineered therapeutic bacteria and are applying this to multiple disease areas. We have submitted an application to the FDA for the Rare Pediatric Disease Designation for Netherton Syndrome, a devastating skin condition that most severely affects children, and are actively progressing programs in atopic dermatitis and psoriasis.

    ResVita Bio is hiring a scientist who is eager to push the boundaries of synthetic biology and metabolic engineering to develop the next generation of bio-therapies to treat deadly and destructive skin diseases. This is an exciting, multi-disciplinary position branching the fields of immunology, dermatology, synthetic biology and metabolic engineering. The scientist will work closely with our CEO to advance our platform to develop and test therapeutic strains for the treatment of skin diseases. The ideal candidate will have experience in murine models, but prior experience with microbial communities is not required.

    As a small start-up, your creativity, values, and managerial skills will help shape ResVita Bio’s path as well as its culture. At ResVita Bio, we believe a diverse workforce will help us achieve our mission to meaningfully change the outcome of many human diseases. Come and play an important role in the development and commercialization of a technology at the forefront of biology and engineering.

    Responsibilities
    Design and construct DNA expression and integration cassettes, building and screening combinatorial strain/enzyme libraries, and analyze and improve of strain performance
    Develop new genetic tools and improve media engineering to improve in vivo strain performance
    Directly test designed strains in skin-damaged murine models
    Collaborate with immunologists to design and interpret animal experiments
    Contribute to the generation and documentation of intellectual property

    Key Qualifications
    PhD in bioengineering, chemical engineering, molecular biology, or biochemistry or a related discipline
    Proficient with microbial genetic engineering and molecular biology bench work
    Direct experience in synthetic biology or metabolic engineering projects
    Ideally, the candidate has some experience with murine models
    Must be able to work independently and have strong organizational and planning skills
    Eagerness to work collaboratively on a team of experts while adapting to the fast-paced needs of an early-stage startup

  • Systems Integration Summer Intern

    Inscripta was founded in 2015 and recently launched the world’s first benchtop Digital Genome Engineering platform. The company’s advanced CRISPR-based platform, consisting of an instrument, reagents, and software, will offer a fully automated workflow that enables multiplexed, trackable editing of cells at an unprecedented scale. Inscripta’s goal is to empower scientists whose gene editing research is stifled by current technical and licensing limitations. By providing this unique platform and engaging in collaborative business practices, such as making its MAD7 CRISPR nuclease free for research purposes, the company enables scientists to realize a new era of biological discovery. Due to rapid growth Inscripta has an opening for a Systems Integration Summer Intern located at our Pleasanton, CA office.

    Summary:
    This paid internship will last a minimum of 10 weeks throughout the summer and will have full-time hours, 40 hours per week, Monday through Friday.

    The Systems Integration team is part of R&D and works on testing and troubleshooting new instruments and automating CRISPR editing workflows.

    This position is hands on, lab bench oriented and will provide the applicant many opportunities to learn new and standard molecular and cell biology lab techniques. In addition, the applicant will learn how to operate and troubleshoot our gene editing instruments. We are looking for exceptional candidates with a passion for science, problem solving, and contributing to the development of new technologies and products.

    Responsibilities:
    The candidate will contribute to the following projects and efforts in the Systems Integration team:
    • Developing next generation, high throughput, CRISPR editing workflows on our instruments. This would involve iPSC cell culture, cell processing, and testing/developing fluidic devices on Inscripta instruments.
    • Creating new SOPs or other protocols for calibrating and/or operating Inscripta instruments.
    • Regular lab maintenance and setting up CRISPR editing runs on our instruments.
    • Contribute to data analysis efforts of instrument data and present work at regular team meetings.

    Requirements:
    • Open to M.S., PhD or Bachelor’s students pursuing a degree in biotechnology, molecular biology, biochemistry, chemistry, or related field.
    • Experience with basic lab techniques including pipetting, aseptic technique, mammalian cell culture, and basic lab equipment.
    • Experience with data collection and data analysis. Experience with data analysis software such as Matlab or JMP is a plus.
    • Proficiency with Microsoft Excel, Powerpoint or similar programs.
    • Detail oriented, with a commitment to keep thorough accurate lab records.

    Inscripta offers a competitive hourly rate for interns. Join us and work with a great team of people developing the world’s first scalable platform for benchtop Digital Genome Engineering. At Inscripta, we don’t just accept difference — we celebrate it, support it, and thrive on it for the benefit of our employees, our innovation, and our community. We are proud to be an equal opportunity workplace because the more inclusive we are as a company, the better our work will be. Inscripta is headquartered in Boulder, CO with offices in Pleasanton and San Diego, CA. This position is located in our Pleasanton, CA office.

  • Applications Development Summer Intern

    Inscripta was founded in 2015 and recently launched the world’s first benchtop Digital Genome Engineering platform. The company is growing aggressively, investing in its leadership, team, and technology with a recent $150mm financing round led by Fidelity and TRowe price. The company’s advanced CRISPR-based platform, consisting of an instrument, reagents, and software, offers a fully automated workflow that enables multiplexed, trackable editing of cells at an unprecedented scale. Inscripta’s mission is to enable scientists to realize the full potential of biology. Inscripta has an opening for a full-time Applications Development Summer Intern located at our Pleasanton, CA office.

    This paid internship will last a minimum of 10 weeks throughout the summer and will have full-time hours, 40 hours per week, Monday through Friday.

    The Applications Development Summer Intern will be responsible for applying novel synthetic biology tools and high-throughput methodologies for rapid phenotyping of microbes including yeast and E. coli. We are looking for talented candidates interested in spending the summer utilizing cutting edge genome engineering technologies and learning to use automation and high-throughput analytics to screen large libraries of genome edited cells.

    Responsibilities:
    • Use Inscripta’s Onyx® platform to build libraries of genome edited cells to support projects in the Applications Development team.
    • Utilize high-throughput (HTP) screening equipment including automation and analytics to evaluate complex phenotypes.
    • Execute on experiments supporting projects within Applications Development.
    • Perform data analysis and generate presentation content.
    • Present scientific results internally.

    Requirements:
    • Pursuing a B.S. in chemistry, biochemistry, molecular biology, biotechnology, biochemical engineering, or equivalent entering junior or senior year in fall 2021 or recent graduate.
    • Experience with molecular biology and working with microbes is desirable.
    • Strong statistical analysis skills, problem-solving skills and ability to think creatively.
    • Excellent communication and presentation skills.
    • Eagerness to learn new skills and a good team player.

    Inscripta offers a competitive hourly rate for interns. Join us for the summer and work with a great team of people developing the world’s first scalable platform for benchtop Digital Genome Engineering. At Inscripta, we don’t just accept difference — we celebrate it, support it, and thrive on it for the benefit of our employees, our innovation, and our community. We are proud to be an equal opportunity workplace because the more inclusive we are as a company, the better our work will be. Inscripta is headquartered in Boulder, CO with offices in Pleasanton and San Diego, CA. This position is located at our Pleasanton, CA office.

  • Computational Science and Engineering Summer Intern – Data Science

    Inscripta was founded in 2015 and recently launched the world’s first benchtop Digital Genome Engineering platform. The company is growing aggressively, investing in its leadership, team, and technology with a recent $150mm financing round led by Fidelity and TRowe price. The company’s advanced CRISPR-based platform, consisting of an instrument, reagents, and software, offers a fully automated workflow that enables multiplexed, trackable editing of cells at an unprecedented scale. Inscripta’s mission is to enable scientists to realize the full potential of biology. Due to rapid growth and recent commercialization, Inscripta has an opening for a Computational Science and Engineering Intern – Data Science located in Pleasanton, CA or Boulder, CO. Remote internships may be possible on a case by case basis.

    Summary:
    The Department of Computational Sciences and Engineering (CoSE) works collaboratively with multi-disciplinary teams throughout Inscripta. CoSE is responsible for addressing a number of genomic, proteomic, experimental design and other relevant questions by building tools, APIs, pipelines, and incorporating mathematical modeling, machine learning and similar data science approaches. We are a multi-disciplinary team made up of software engineers, data scientists, and bioinformaticians. We are looking for exceptional candidates to spend the summer working at Inscripta on data science projects such as model training, data engineering, and data visualization

    Responsibilities:
    Internship projects will be tailored to the skills and interests of each intern. Some potential projects are listed below as examples.
    • Develop predictive models to improve the performance mammalian genome engineering systems.
    • Explore novel deep learning architectures and ensemble learning.
    • Build dashboards for data and/or model exploration.

    Requirements:
    Program Requirements
    • Open to M.S., PhD or Bachelor’s students pursuing a degree in computer science, engineering, bioinformatics, biology, biochemistry, physics, statistics, or a related field.
    • Must have completed at least 3 years of an undergraduate program to be eligible.
    • This internship will last a minimum of 12 weeks throughout the summer and will have full-time hours, 40 hours per week, Monday through Friday.

    Minimum Qualifications
    • Knowledge of Python, R, or other object-oriented programming language.
    • Experience analyzing and extracting insight from high-dimensional datasets.
    • Coursework or projects related to machine learning.
    • Some software development skills, including a working knowledge of git versioning and branching.
    • Ability to communicate clearly about technical aspects of a project in group presentations and written documentation.
    • Experience working collaboratively on a team or project.

    Desired Qualifications
    Projects will vary depending upon the candidate’s background, but experience in one or more of the following skills is desired:
    • Experience with DNA/RNA sequencing data analysis.
    • Familiarity with modern machine learning methods and models, preferably neural networks.
    • Experience training and validating the performance of machine learning models.
    • Knowledge of CRISPR biology and/or mammalian genomics.

    Inscripta offers a competitive hourly rate for interns. Join us for the summer and work with a great team of people creating cutting edge technology in the world’s first scalable platform for benchtop Digital Genome Engineering. At Inscripta, we don’t just accept difference — we celebrate it, support it, and thrive on it for the benefit of our employees, our innovation, and our community. We are proud to be an equal opportunity workplace because the more inclusive we are as a company, the better our work will be. Inscripta is headquartered in Boulder, CO with offices in Pleasanton and San Diego, CA. This position is located in Pleasanton, CA or Boulder, CO locations. Remote internships may be possible on a case by case basis.

  • Computational Science and Engineering Summer Intern – Software

    Inscripta was founded in 2015 and recently launched the world’s first benchtop Digital Genome Engineering platform. The company is growing aggressively, investing in its leadership, team, and technology with a recent $150mm financing round led by Fidelity and TRowe price. The company’s advanced CRISPR-based platform, consisting of an instrument, reagents, and software, offers a fully automated workflow that enables multiplexed, trackable editing of cells at an unprecedented scale. Inscripta’s mission is to enable scientists to realize the full potential of biology. Due to rapid growth and recent commercialization, Inscripta has an opening for a Computational Science and Engineering Intern – Software located in Pleasanton, CA or Boulder, CO. Remote internships may be possible on a case by case basis.

    Summary:
    The Department of Computational Sciences and Engineering (CoSE) works collaboratively with multi-disciplinary teams throughout Inscripta. CoSE is responsible for addressing a number of genomic, proteomic, experimental design and other relevant questions by building tools, APIs, pipelines, and incorporating mathematical modeling, machine learning and similar data science approaches. We are a multi-disciplinary team made up of software engineers, data scientists, and bioinformaticians. We are looking for exceptional candidates to spend the summer working at Inscripta on software and infrastructure projects such as improving cloud infrastructure components, developing dashboards for security and usage of components, and expanding functionality of existing services and APIs.

    Responsibilities:
    Internship projects will be tailored to the skills and interests of each intern. Some potential projects are listed below as examples only.
    • Develop microservices for genomic file uploads, format validation and conversions to other formats.
    • Develop dashboards for tracking uptime and resource usage of services, how often a data pipeline is run by customers and for what duration, and to monitor security events.
    • Optimize or automate infrastructure maintenance by utilizing infrastructure-as-code services such as Salt and Terraform.
    • Improve automated CI/CD practices using Jenkins and integrated services.

    Requirements:
    Program Requirements
    • Open to M.S., PhD or Bachelor’s students pursuing a degree in computer science, engineering, bioinformatics, biology, biochemistry, physics, statistics, or a related field.
    • Must have completed at least 3 years of an undergraduate program to be eligible.
    • This internship will last a minimum of 12 weeks throughout the summer and will have full-time hours, 40 hours per week, Monday through Friday.

    Minimum Qualifications
    • Knowledge of Python, Java, or other object-oriented programming language.
    • Software development skills, including a working knowledge of git versioning and branching.
    • Ability to communicate clearly about technical aspects of a project in group presentations and written documentation.
    • Experience working collaboratively on a team or project.

    Desired Qualifications
    Projects will vary depending upon the candidate’s background, but experience in one or more of the following skills is desired:
    • Familiarity with developing or integrating with web APIs using Python.
    • Familiarity with testing and CI/CD development including pytest, Jenkins, etc.
    • Familiarity with developing interactive visualizations using Rstudio, D3.js, plotly, etc.
    • Exposure to big data technologies such as SQL and NoSQL databases and Spark infrastructure.
    • Exposure to cloud infrastructure such as AWS’ EC2, S3, ECR, and Batch environment.
    • Exposure to containerization technologies such as Docker, Singularity and Kubernetes.

    Inscripta offers a competitive hourly rate for interns. Join us for the summer and work with a great team of people creating cutting edge technology in the world’s first scalable platform for benchtop Digital Genome Engineering. At Inscripta, we don’t just accept difference — we celebrate it, support it, and thrive on it for the benefit of our employees, our innovation, and our community. We are proud to be an equal opportunity workplace because the more inclusive we are as a company, the better our work will be. Inscripta is headquartered in Boulder, CO with offices in Pleasanton and San Diego, CA. This position is located in Pleasanton, CA or Boulder, CO locations. Remote internships may be possible on a case by case basis.

  • Computational Science and Engineering Summer Intern – Biosecurity

    Inscripta was founded in 2015 and recently launched the world’s first benchtop Digital Genome Engineering platform. The company is growing aggressively, investing in its leadership, team, and technology with a recent $150mm financing round led by Fidelity and TRowe price. The company’s advanced CRISPR-based platform, consisting of an instrument, reagents, and software, offers a fully automated workflow that enables multiplexed, trackable editing of cells at an unprecedented scale. Inscripta’s mission is to enable scientists to realize the full potential of biology. Due to rapid growth and recent commercialization, Inscripta has an opening for a Computational Science and Engineering Intern – Biosecurity located in Pleasanton, CA or Boulder, CO. Remote internships may be possible on a case by case basis.

    Summary:
    The Department of Computational Sciences and Engineering (CoSE) works collaboratively with multi-disciplinary teams throughout Inscripta. CoSE is responsible for addressing a number of genomic, proteomic, experimental design and other relevant questions by building tools, APIs, pipelines, and incorporating mathematical modeling, machine learning and similar data science approaches. We are a multi-disciplinary team made up of software engineers, data scientists, and bioinformaticians. We are looking for exceptional candidates to spend the summer working at Inscripta on Biosecurity related tasks.

    Responsibilities:
    Work with the Biosecurity team to improve and expand sequence screening algorithms, using these or related strategies;
    • Assemble and leverage appropriate datasets to assess biosecurity screening approaches.
    • Benchmark existing approaches using a range of input sequence variants.
    • Improve taxonomic assessment of novel genomes.
    • Develop innovative strategies to improve robustness and sensitivity of our sequence screening processes.
    • Strategize and prototype novel approach to evaluate functional impact of individual edits in organisåmal context.

    Requirements:
    Program Requirements
    • Open to M.S., PhD or Bachelor’s students pursuing a degree in computer science, engineering, bioinformatics, biology, biochemistry, physics, statistics, or a related field.
    • Must have completed at least 3 years of an undergraduate program to be eligible.
    • This internship will last a minimum of 12 weeks throughout the summer and will have full-time hours, 40 hours per week, Monday through Friday.

    Minimum Qualifications
    • Familiarity with high level programming language such as python, R, or similar.
    • Application of biology principles to computational challenges.
    • Strong problem solving, statistical, and mathematical skills.
    • Strong communication skills.
    • Experience working collaboratively on a team or project.

    Desired Qualifications
    Projects will vary depending upon the candidate’s background, but experience in one or more of the following skillsets is expected:
    • Familiarity with a broad range of bioinformatics software and algorithms and experience using them on large data sets.
    • Familiarity with machine learning approaches for sequence classification.
    • Graphical approaches to genome variant detection and representation.

    Inscripta offers a competitive hourly rate for interns. Join us for the summer and work with a great team of people creating cutting edge technology in the world’s first scalable platform for benchtop Digital Genome Engineering. At Inscripta, we don’t just accept difference — we celebrate it, support it, and thrive on it for the benefit of our employees, our innovation, and our community. We are proud to be an equal opportunity workplace because the more inclusive we are as a company, the better our work will be. Inscripta is headquartered in Boulder, CO with offices in Pleasanton and San Diego, CA. This position is located in Pleasanton, CA or Boulder, CO locations. Remote internships may be possible on a case by case basis.

  • Sr. Bioinformatics Scientist II/ Staff Bioinformatics Scientist

    Inscripta was founded in 2015 and recently launched the world’s first benchtop Digital Genome Engineering platform. The company is growing aggressively, investing in its leadership, team, and technology with a recent $150mm financing round led by Fidelity and TRowe price. The company’s advanced CRISPR-based platform, consisting of an instrument, reagents, and software, offers a fully automated workflow that enables multiplexed, trackable editing of cells at an unprecedented scale. Inscripta’s mission is to enable scientists to realize the full potential of biology. Due to rapid growth and recent commercialization, Inscripta has an opening for a Senior Bioinformatics Scientist II/ Staff Bioinformatics Scientist in the Bioengineering Software Design team located in our Pleasanton, CA or San Diego, CA or Boulder, CO offices or work remotely in the U.S..

    Summary:
    The Senior Bioinformatics Scientist II/ Staff Bioinformatics Scientist is a full-time individual-contributor position, to which you would devote all your professional effort. You will be a member of an incredibly talented interdisciplinary team, and your primary responsibility will be devoted to creating and improving library designs and library design tools needed to support Product Development and Commercial teams’ development of cells comprised of thousands of precise genomic edits. Come work with us to build the tools that will power a new era of genome engineering!

    Responsibilities:
    • Create design library orders to support our R&D Product Development and Commercial teams.
    • Develop, deploy, and train others to use new library design tools that help our Product Development team iterate through the design-build-test-learn cycle more quickly.
    • Work closely with applications scientists to document & codify library design best practices and strategies that leverage Inscripta’s technology platform.
    • Develop backend software to support our design library pipeline. This responsibility includes architecture decisions, feature augmentation, refactoring, testing, and documentation of code as well as participation in scrum team activities.
    • Such other matters as may be determined by yourself and the Company.

    Requirements:
    • A Bachelor’s degree in a technical or scientific area. An advanced degree is strongly preferred.
    • A minimum of 7-10 years of experience (or equivalent with advanced degree).
    • Firm understanding of molecular biology, metabolic engineering, biophysics, and biochemistry is strongly preferred.
    • A strong working knowledge of bioinformatics file types like VCF, GB, GFF3, BED, and SAM/BAM.
    • Familiarity with bioinformatics databases like EcoCyc, UniProt, NCBI, Pfam, Rfam, YGD, ENSEMBL, UCSC genome browser.
    • A strong working knowledge of Python in OO setting and familiarity with packages like biopython, pandas, numpy, and scikit-learn.
    • Experience managing user interfaces such as Shiny (from RStudio) or Dash (from plot.ly) is a plus.
    • Software development skills, including a working knowledge of version control systems, continuous integration processes, and Agile development techniques – experience with Scrum is preferred.
    • Enthusiasm for developing software as part of a team is a must.
    • Patience and tenacity regarding working in a startup culture with a complex code base is a must.
    • 1+ years of experience writing production code in a team setting is preferred.
    • Energetic and motivated self-starter with excellent analytical, problem solving, communication, and presentation skills.
    • Special consideration will be given to candidates with expertise in synthetic biology, metabolic engineering, and advanced genome editing tools and methodologies.
    • Special consideration will be given to candidates with an excellent track-record of publications and/or other scientific achievements.

    Inscripta offers a competitive base salary, bonus plan, benefits package, 401k match, and an attractive equity program to all team members. Join us and work with a cutting edge organization creating cutting edge technology. At Inscripta, we don’t just accept difference — we celebrate it, support it, and thrive on it for the benefit of our employees, our innovation, and our community. We are proud to be an equal opportunity workplace because the more inclusive we are as a company, the better our work will be. Inscripta is headquartered in Boulder, CO with offices in Pleasanton and San Diego, CA. This position can work out of either our Pleasanton, CA or San Diego, CA or Boulder, CO offices, or work remotely in the U.S..

  • Scientist/ Sr. Scientist, Applications Development

    Inscripta was founded in 2015 and recently launched the world’s first benchtop Digital Genome Engineering platform. The company is growing aggressively, investing in its leadership, team, and technology with a recent $150mm financing round led by Fidelity and TRowe price. The company’s advanced CRISPR-based platform, consisting of an instrument, reagents, and software, offers a fully automated workflow that enables multiplexed, trackable editing of cells at an unprecedented scale. Inscripta’s mission is to enable scientists to realize the full potential of biology. Due to rapid growth and recent commercialization, Inscripta has an opening for a Scientist/Senior Scientist located in our Boulder, CO office.

    Summary:
    As a member of the Applications Development team, the Scientist/Senior Scientist will be one of the first internal customers of OnyxTM – Inscripta’s Digital Genome Engineering platform, applying our massively parallel genome engineering capability to tackle cutting edge research projects in S. cerevisiae, E. coli and other microbes. They will conceive, plan, and execute large scale projects in diverse research areas including functional genomics, biochemistry, cell biology, experimental evolution, systems biology, etc., while communicating results with the broader scientific community through conferences, publications, seminars, etc. The Scientist/Senior Scientist will work closely with internal and external collaborators on cross-functional teams, communicating and collaborating effectively with scientists, engineers, data scientists, and software developers.

    Responsibilities:
    • Develop genome engineering applications in S. cerevisiae, E. coli, and other microbes which demonstrate the power of Inscripta’s technology across research areas.
    • Work with collaborators in diverse academic fields to understand their research goals & experimental systems.
    • Design and execute experiments across a wide range of projects; analyze and interpret large, diverse datasets.
    • Publish scientific results and present data at conferences, seminars, etc.
    • Leverage knowledge from Onxy-based research projects to provide scientific insight to customers and internal commercial team members.
    • Provide feedback and voice of customer to guide the product development team.

    Requirements:
    • PhD in genetics, cell biology, microbiology, or related field is required. 3+ years post-PhD research experience is preferred.
    • Strong molecular biology and microbiology techniques including PCR, cloning, transformation, and strain engineering in one or more microbial systems are required.
    • Strong written and verbal communication skills are required.
    • Strong skills in data analysis, visualization, and interpretation are required. Deeper knowledge in bioinformatics, statistics, and/or experience with one or more scripting languages (R, Python, etc.) is a plus.
    • Research experience using S. cerevisiae and/or E. coli as a model organism is preferred. A broad understanding of microbial genetics and cell biology is a plus.
    • Experience with NGS, highly multiplexed experimental techniques, and/or laboratory automation is preferred.

    Inscripta offers a competitive base salary, bonus plan, benefits package, 401k match and an attractive equity program to all team members. Join us and work with a cutting edge organization creating cutting edge technology. At Inscripta, we don’t just accept difference — we celebrate it, support it, and thrive on it for the benefit of our employees, our innovation, and our community. We are proud to be an equal opportunity workplace because the more inclusive we are as a company, the better our work will be. Inscripta is headquartered in Boulder, CO with offices in Pleasanton and San Diego, CA. This position is located in our Boulder headquarters office.

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