Job Board

  • Scientist/ Senior Scientist

    Inscripta was founded in 2015 and recently launched the world’s first benchtop Digital Genome Engineering platform. The company is growing aggressively, investing in its leadership, team, and technology with a recent $150mm financing round led by Fidelity and TRowe price. The company’s advanced CRISPR-based platform, consisting of an instrument, reagents, and software, offers a fully automated workflow that enables multiplexed, trackable editing of cells at an unprecedented scale. Inscripta’s mission is to enable scientists to realize the full potential of biology. Due to rapid growth and recent commercialization, Inscripta has an opening for a Scientist/Senior Scientist in the Enzyme Engineering group located Pleasanton, CA.

    Summary
    As a Scientist/Senior Scientist in the Enzyme Engineering group, you will part of a diverse team focused on developing enzymes to advance Inscripta’s cell engineering platform. The ideal candidate will have a track record of success in developing or improving genome editing tools. You will be responsible for planning, executing and reporting on experiments and work closely with a world class team of Engineers, Biologists, and Computer Scientists.

    Responsibilities
    • Work on rapidly prototyping and improving CRISPR-based genome editing systems in mammalian cell culture.
    • Develop cell-based and in vitro assays for enzyme improvement efforts.
    • Leverage high-throughput molecular biology to build large sets of DNA reagents for testing in cell culture.
    • Keep up with relevant literature and advances in the genome editing field.
    • Identify innovative solutions to solve key scientific challenges required for program success.
    • Communicate experimental results clearly within a multidisciplinary team to advance program objectives.

    Required qualifications
    • Ph.D in bioengineering, biochemistry, cell and molecular biology, or a related discipline.
    • Hands-on experience developing and optimizing genome editing systems.
    • Experience desiging and executing high-throughput cloning workflows to build reagents (eg. Gibson cloning, Golden Gate, etc.).
    • Strong written and oral communication skills.
    • Experience analyzing complex data sets and developing actionable conclusions.
    • Track record of creativity and problem solving.

    Preferred qualifications
    • Hands-on experience with mammalian cell culture.
    • Experience analyzing large experimental data sets using scripting tools such as R, Matlab or Python to draw statistically significant conclusions.

    Inscripta offers a competitive base salary, bonus plan, benefits package, 401k match, and an attractive equity program to all team members. Starting Salary Range: $100,000 to $150,000 per year. This salary range is provided per current averages and expectations. The salary and job title for this opening will be based on the selected candidate’s qualifications and experience and may be outside this range. Join us and work with a cutting edge organization creating cutting edge technology. At Inscripta, we don’t just accept difference — we celebrate it, support it, and thrive on it for the benefit of our employees, our innovation, and our community. We are proud to be an equal opportunity workplace because the more inclusive we are as a company, the better our work will be. Inscripta is headquartered in Boulder, CO with offices in Pleasanton and San Diego, CA. This position is located in our Pleasanton office.

  • Post Doctoral Associate

    A postdoctoral associate position is available in the research laboratory of Dr. Kevin A. Kuehn at the University of Southern Mississippi. This position is part of a 4-year collaborative project funded through DARPA-Arcadia (https://www.darpa.mil/news-events/2021-09-14) entitled IMPEDE: Inhibiting Molds with Probiotic Ensembles from Diverse Environments. The successful applicant is expected to have prior research training in microbial ecology, mycology, or microbiology, and have excellent communication skills. Applicants are expected to have experience in one or more of the previously mentioned fields, including a promising record of publications in peer-reviewed journals. Applicants having experience in high-resolution light and fluorescent microscopy and/or hyperspectral imaging, would be considered a plus. Applicants must have completed their Ph.D. before starting and must be eligible to work in the United States. Duties of the postdoctoral associate will include research pursuant to the project objectives, peer-reviewed publication of research findings, and working closely with project collaborators from Columbia University, Massachusetts Institute of Technology, University of Wisconsin-Madison, and the Air Force Research Laboratory (AFRL). The salary is competitive and includes a comprehensive benefits package. The anticipated start date is Fall 2022 but is negotiable.

    The University of Southern Mississippi, a Carnegie Research I institution with approximately 14,000 students, is located in Hattiesburg, Mississippi, with additional campuses located nearby on the Mississippi Gulf Coast. This position will be based at the main campus in Hattiesburg. Hattiesburg is the medical, commercial, and cultural center of south Mississippi and is ranked among the top five small metropolitan areas in the United States. The School of Biological, Environmental, and Earth Sciences currently has 22 tenured-tenure track faculty with research strengths in ecology, evolution, molecular biology, and microbiology. Further information about the school may be found at www.usm.edu/biological-sciences.

    Applicants should apply via the Southern Miss website at https://jobs.usm.edu (job posting # req2720) by submitting a cover letter describing your research experience and future goals, a curriculum vitae, pertinent publication reprints, and the contact information for 3 references. Review of applicants will begin September 15, 2022 and continue until the position is filled. Questions should be directed to Dr. Kevin A. Kuehn (kevin.kuehn@usm.edu). The University of Southern Mississippi is an affirmative action/equal opportunity employer/Americans with disabilities act institution. The University of Southern Mississippi encourages minorities, women, veterans, and persons with disabilities to apply.

  • Bioinformatics Software Engineer

    Inscripta was founded in 2015 and recently launched the world’s first benchtop Digital Genome Engineering platform. The company is growing aggressively, investing in its leadership, team, and technology with a recent $150mm financing round led by Fidelity and TRowe price. The company’s advanced CRISPR-based platform, consisting of an instrument, reagents, and software, offers a fully automated workflow that enables multiplexed, trackable editing of cells at an unprecedented scale. Inscripta’s mission is to enable scientists to realize the full potential of biology. Due to rapid growth and recent commercialization, Inscripta has an opening for a Bioinformatics Software Engineer located in Pleasanton/Boulder/Remote.

    Summary:
    The Bioinformatics Software Engineer will be responsible for creating the software our customers will depend on to design and analyze libraries of thousands of precisely edited cells. You will be part of an incredibly talented team of software engineers and computational scientists, leveraging your Python skills to develop novel bioinformatics focused APIs and applications. Come work with us to build the software that will power a new era of genome engineering.

    Responsibilities:
    • Write the customer-facing code that enables our customers to construct cell libraries with thousands of uniquely edited genomes.
    • Design and deploy new API servers to communicate with Inscripta’s Engineering Platform.
    • Work with cloud platforms like AWS to deploy customer facing software stacks.
    • Collaborate closely with a diverse group of scientists and engineers in a Scrum team.
    • Ensure robust verification and validation of Inscripta’s code.
    • Occasionally work with other team members to design experiments to validate the results of novel bioinformatic algorithms.

    Requirements:
    Required skillsets
    • A Bachelor’s degree or higher in a technical or scientific area (e.g. computer science, engineering, biology, biochemistry, physics, or related fields).
    • Strong knowledge of Python in an object-oriented setting.
    • Familiarity with popular Python packages like pandas, numpy, and scikit-learn.
    • Experience with constructing unit and integration tests using packages like pytest and tox.
    • A strong ethic of creating robust software design documentation.
    • A strong interest in working with bioinformatics concepts is a must.
    • Software development skills, including experience with version control systems like git and continuous integration processes.
    • Ability to communicate technical problems effectively.

    Additional desired skillsets
    • Familiarity with constructing API servers using python frameworks like flask is a strong plus.
    • Industry experience writing production code in a team setting
    • Experience working in an Agile/Scrum environment.
    • Familiarity with bioinformatics software, algorithms, and data formats is strongly desired.
    • Experience with leveraging cloud platforms like AWS strongly desired. Experience with Terraform is a plus.
    • Familiarity with container technologies such as Docker. Experience with Kubernetes is a plus.
    • Strong problem solving, statistical, and mathematical skills.
    • A desire to work collaboratively in a fast-moving software development team.

    Inscripta offers a competitive base salary, bonus plan, benefits package, 401k match, and an attractive equity program to all team members. Base Salary Range: $110,000 to $160,000 per year. Base salary range provided per current averages and expectations. The salary and job title for this opening will be based on the selected candidate’s qualifications and experience and may be outside this range. Join us and work with a cutting edge organization creating cutting edge technology. At Inscripta we don’t just accept difference — we celebrate it, support it, and thrive on it for the benefit of our employees, our innovation, and our community. We are proud to be an equal opportunity workplace because the more inclusive we are as a company, the better our work will be. Inscripta is headquartered in Boulder, CO with offices in Pleasanton and San Diego, CA. The role can work out of Boulder or Pleasanton or work remotely.

  • Scientist / Senior Scientist

    Inscripta was founded in 2015 and recently launched the world’s first benchtop Digital Genome Engineering platform. The company is growing aggressively, investing in its leadership, team, and technology with a recent $150mm financing round led by Fidelity and T Rowe Price. The company’s advanced CRISPR-based platform, consisting of an instrument, reagents, and software, offers a fully automated workflow that enables multiplexed, trackable editing of cells at an unprecedented scale. Inscripta’s mission is to enable scientists to realize the full potential of biology. Due to rapid growth and recent commercialization, Inscripta has an opening for a Systems Integration Scientist / Sr. Scientist located in our Pleasanton, CA office.

    Summary:
    We are looking for an outstanding Scientist to drive CRISPR-based DNA editing projects on early-stage instrumentation through to commercialization. This individual will innovate in areas of assay development, process optimization, and hardware automation. Essential aspects of this position include: project leadership, design and execution of key experiments in team-based projects, and superior data communication skills. The right candidate will enthusiastically leverage their creativity and research experience to build an automated genetic-engineering platform in a fast-paced team environment of passionate scientists and engineers.

    Responsibilities:
    • Provide scientific leadership in a technical team that is building a high-throughput genetic-engineering platform (instrument, consumables, software).
    • Execute complex, highly multiplexed experiments within a team.
    • Develop robust system performance through elegant and automated workflows.
    • Perform molecular biology techniques: PCR, genetic-engineering, and mammalian cell culture.
    • Conduct detailed data analysis and provide recommendations based on technical results.
    • Maintain detailed experimental records and contribute to writing and editing SOPs.
    • Present clear and concise written and oral communications to colleagues and supervisors.

    Requirements:
    • Ph.D. in molecular biology, cellular biology, bioengineering, materials science, or a related discipline.
    • Demonstrated record of innovation in molecular or cellular biology, including tools development. Preference given to experience with mammalian cells.
    • Experience converting prototype devices into fully automated modules and instruments.
    • Direct experience with molecular biology techniques such as: PCR, qPCR, nucleic acid purification, and/or genome editing.
    • Familiarity with next generation sequencing, sequencing library preparation, and other genomic platforms.
    • Desire to work in a team environment and collaborate closely with other cross-functional and geographically-distributed teams. Occasional US travel may be required.
    • Ability to learn quickly in a fast-paced environment and comfortable working across all stages of development (R&D through to commercialization).

    Inscripta offers a competitive base salary, bonus plan, benefits package, 401k match, and an attractive equity program to all team members. Starting Salary Range: $90,000 to $140,000 per year. This salary range provided per current averages and expectations. The salary and job title for this opening will be based on the selected candidate’s qualifications and experience and may be outside this range. Join us and work with a cutting edge organization creating cutting edge technology. At Inscripta, we don’t just accept difference — we celebrate it, support it, and thrive on it for the benefit of our employees, our innovation, and our community. We are proud to be an equal opportunity workplace because the more inclusive we are as a company, the better our work will be. Inscripta is headquartered in Boulder, CO with offices in Pleasanton and San Diego, CA. This position is located in our Pleasanton office.

  • Post doctoral fellow

    Position Summary
    We seek a doctorate level scientist to develop the synthetic genomics technology called Genome Transplantation (2,3). This method installs a complete, typically synthetic, bacterial genome in a suitable bacterial recipient cell, so that the donated genome commandeers the recipient cell to produce a new cell with the genotype and phenotype of the donated genome. The JCVI developed this method over a decade ago, and it was critical in the production of the world’s first cell with a chemically synthesized genome, JCVI-syn1.0 (1), which is a strain of Mycoplasma mycoides. To date, genome transplantation has only been demonstrated for a small set of mycoplasma species (4). We plan to establish this method for use in non-mycoplasma species. Genome transplantation techniques for non-mycoplasmas would catalyze an expansion of the field of synthetic genomics. Efforts that constructed Escherichia coli strains with synthetic genomes had to exchange ~50 kb synthetic genome segments for their corresponding wild type segments in a time-consuming series of more than 50 iterative steps. Had genome transplantation been available to these projects, they could have moved much faster and other projects would have been funded if the method to boot up synthetic genomes was not so difficult. We will also develop a methodology to perform genome transplantation in microfluidic devices as opposed to the original test tube method.

    This scientist will be located at the JCVI campus in Rockville, MD. They will be supervised by the JCVI’s head of Synthetic Biology, John Glass, and collaborate closely with Elizabeth Strychalski, a physicist/synthetic biologist at the National Institute of Standards and Technology in Gaithersburg, MD. In the second year of the project this scientist will spend a month working in Bordeaux, France at the Institut National de la Recherche Agronomique (INRA) working with Carole Lartigue, inventor of genome transplantation.

    Relevant Literature
    1. Gibson DG, Glass JI, Lartigue C, Noskov VN, Chuang RY, Algire MA, et al. Creation of a bacterial cell controlled by a chemically synthesized genome. Science. 2010;329(5987):52-6. Epub 2010/05/22. doi: 10.1126/science.1190719. PMID: 20488990.
    2. Lartigue C, Glass JI, Alperovich N, Pieper R, Parmar PP, Hutchison CA, 3rd, et al. Genome transplantation in bacteria: changing one species to another. Science. 2007;317(5838):632-8. doi: 10.1126/science.1144622. PubMed PMID: 17600181.
    3. Lartigue C, Vashee S, Algire MA, Chuang RY, Benders GA, Ma L, et al. Creating bacterial strains from genomes that have been cloned and engineered in yeast. Science. 2009;325(5948):1693-6. Epub 2009/08/22. doi: 10.1126/science.1173759. PMID: 19696314.
    4. Labroussaa F, Lebaudy A, Baby V, Gourgues G, Matteau D, Vashee S, et al. Impact of donor-recipient phylogenetic distance on bacterial genome transplantation. Nucleic acids research. 2016;44(17):8501-11. Epub 2016/08/05. doi: 10.1093/nar/gkw688. PMID: 27488189

    Essential Functions
    • Assists with conducting research in defined areas related to the goals of the Institute and the project to improve Genome Transplantation technology.
    • Designs and executes scientific experiments and/or scientific software; analyzes and interprets experimental results/data; reviews findings with Dr. Glass and Dr. Strychalski.
    • Maintains detailed and complete records of laboratory work and data analysis, as well as abides by the data management plan of the Institute. Organizes and archives data for others to access later.
    • Trains and supervises research associates and/or students and/or data specialists assigned to the Genome Transplantation Project.
    • Publishes results of scientific work in peer-reviewed journals.
    • Keeps current with knowledge in relevant scientific discipline through continued reading of the literature.
    • Attends and participates in national and international scientific meetings.
    • Participates in JCVI laboratory meetings and scientific working groups.
    • Interacts with the Laboratory Director and Department Director on matters of mutual scientific interest.
    • Works cooperatively with other staff when necessary to achieve JCVI research goals.
    • Abides by environmental, health and safety policies and procedures. This includes reporting potential hazards and when necessary helping to implement solutions to ensure safety and respect for the environment.
    • Performs other duties as assigned.
    • Strictly adheres to all documented JCVI policies and procedures to include carrying out all functions required of Institute employees (i.e. completion of timesheets in an accurate and timely manner).

    Prerequisites
    • M.D. or Ph.D. in relevant scientific discipline, such as Molecular Biology, Biochemistry, Pharmacology, Immunology, Microbiology, Neuroscience or Computer Science required. Hands-on laboratory experience preferably in an independent project preferred. Supervisory experience preferred.
    • High level of discretion for confidential work and information; ability to appropriately handle critical information and sensitive situations.
    • Ability to conduct investigations in relevant scientific areas.
    • Must be able to formulate experimental hypotheses and analyze and interpret scientific data.
    • Strong computer aptitude, including experience with word processing and/or spreadsheet software and/or data analysis and database software.
    • Familiarity with nano- and microfluidics and/or optical microscopy preferred.
    • Familiarity with standard laboratory safety procedures.
    • Excellent organization, communication, and time management skills.
    • Flexibility to handle a variety of tasks and shift priorities simultaneously.
    • Strong interpersonal skills; ability to effectively interact with all levels of staff and external contacts; ability to work as an effective team member.
    • Cooperative and service-oriented attitude; must be able to work under pressure and maintain a professional demeanor.
    • Ability to use sound judgment to effectively solve problems within the scope of the position.
    • High level of initiative and ability to work with minimum supervision.
    • Superior verbal and written communications skills.

    Work Environment
    The work environment characteristics described here are representative of those a teammate encounters while performing the essential functions of this job. Reasonable accommodations may be made to enable individuals with disabilities to perform the essential functions.

    • Moderate noise (i.e. business office with computers, phone, and printers, light traffic)
    • Ability to work in a confined area.
    • Ability to sit at a computer terminal for an extended period of time.
    • Ability to stand and/or sit for an extended period of time while working in the lab.

    Physical Demands
    The physical demands described here are representative of those that must be met to successfully perform the essential functions of this job. Reasonable accommodations may be made to enable individuals with disabilities to perform the essential functions.

    • While performing the duties of this job, the employee is regularly required to, stand, sit; talk, hear, and use hands and fingers to operate a computer and telephone keyboard reach, stoop kneel to install computer equipment
    • Specific vision abilities required by this job include close vision requirements due to computer and lab work
    • Light to moderate lifting is required

  • Senior Lab Automation Systems Engineer

    Inscripta was founded in 2015 and recently launched the world’s first benchtop Digital Genome Engineering platform. The company is growing aggressively, investing in its leadership, team, and technology with a recent $150mm financing round led by Fidelity and TRowe price. The company’s advanced CRISPR-based platform, consisting of an instrument, reagents, and software, offers a fully automated workflow that enables multiplexed, trackable editing of cells at an unprecedented scale. Inscripta’s mission is to enable scientists to realize the full potential of biology. Due to rapid growth and recent commercialization, Inscripta has an opening for a Senior Lab Automation Systems Engineer located in Pleasanton, CA.

    Summary
    We are looking for a Senior Lab Automation Systems Engineer to join our Information Systems & Software group, working in close conjunction with our Biochemistry group, operations, and other R&D teams. We are looking for a candidate who can gather complex and often unclear business needs and translate them into usable system requirements as well as identify, document, and execute test cases for a variety of software packages. Our ideal candidate is one who can translate between R&D wet bench research and automated liquid handling development. This role requires an experienced candidate with a strong molecular biology background, strong written and verbal communication skills, and demonstrated automated liquid handling experience. You would be primarily responsible for R&D and automation development activities but may also participate in other corporate matters.

    Responsibilities
    • Working with R&D scientists to adapt benchtop protocols to automated systems and developing tasks to execute these protocols to meet key performance metrics.
    • Working in conjunction with scientific teams to execute automated workflows.
    • Working with software teams to integrate lab automation equipment into laboratory information management systems to track samples through complex workflows and capture data associated with the workflow processes.
    • Requirements gathering and documentation efforts in support of laboratory automation projects.
    • Aiding in the selection, procurement, installation, and validations of flexible laboratory automation systems which can be used in a high throughput laboratory environment.

    Requirements
    • Experience with molecular biology tools including cloning, DNA purification and sequencing.
    • 3+ years of work experience with automated liquid handling systems such as Tecan EVO/Fluent, Beckman Biomek FX/NX, Agilent Bravo, etc.
    • Experience adapting benchtop protocols to automated systems.
    • Experience writing comprehensive bug reports using software bug/feature request tracking systems in a research/software/hardware development team environment.
    • Desire to work in a team environment and collaborate closely with other cross-functional teams.
    • Ability to learn quickly in a fast-paced startup environment.
    • MS or BS in Life Sciences or Engineering is preferred.

    Inscripta offers a competitive base salary, bonus plan, benefits package, 401k match, and an attractive equity program to all team members. Join us and work with a cutting edge organization creating cutting edge technology. At Inscripta, we don’t just accept difference — we celebrate it, support it, and thrive on it for the benefit of our employees, our innovation, and our community. We are proud to be an equal opportunity workplace because the more inclusive we are as a company, the better our work will be. Inscripta is headquartered in Boulder, CO with offices in Pleasanton and San Diego, CA. This position is located in our Pleasanton, CA office location.

  • Research Associate

    Inscripta was founded in 2015 and recently launched the world’s first benchtop Digital Genome Engineering platform. The company is growing aggressively, investing in its leadership, team, and technology with a recent $150mm financing round led by Fidelity and TRowe price. The company’s advanced CRISPR-based platform, consisting of an instrument, reagents, and software, offers a fully automated workflow that enables multiplexed, trackable editing of cells at an unprecedented scale. Inscripta’s mission is to enable scientists to realize the full potential of biology. Due to rapid growth and recent commercialization, Inscripta has an opening for a Systems Integration Research Associate located in Boulder, CO.

    Summary
    We are looking for an outstanding Research Associate to support and drive CRISPR-based DNA editing projects. This individual will innovate in areas of assay development, process optimization, and product automation. Essential aspects of this position include: following established protocols, troubleshooting, innovative solutions, design and execution of informative experiments, and superior data analysis. The right candidate will enthusiastically leverage their creativity, and research experience to build an industry-leading genetic-engineering platform in a highly innovative, team-oriented, fast-paced R&D environment.

    Responsibilities
    • Provide scientific support in a technical team that is building a high-throughput genetic-engineering platform.
    • Execute complex, highly multiplexed experiments.
    • Perform microbiology and molecular biology techniques: culturing microorganisms, PCR, genetic-engineering, and robotic liquid handling.
    • Conduct detailed data analysis and provide recommendations based on technical results.
    • Maintain detailed experimental records.
    • Present clear and concise written and oral communications to colleagues and supervisors.

    Requirements
    • Direct experience with microbiology and molecular biology techniques such as: culturing microorganisms, PCR, qPCR, nucleic acid purification, and genome editing.
    • Demonstrated record of innovation in molecular or cellular biology preferred.
    • Experience converting prototype devices into fully automated modules and instruments.
    • Familiarity with next generation sequencing, sequencing library preparation, and other genomic platforms.
    • Desire to work in a team environment and collaborate closely with other cross-functional and geographically distributed teams.
    • Ability to learn quickly in a fast-paced startup environment.
    • BS in molecular biology, bioengineering, or a related discipline.

    Inscripta offers a competitive base salary, bonus plan, benefits package, 401k match, and an attractive equity program to all team members. Starting Salary Range: $50,000 – $60,000 per year. This salary range is provided per current averages and expectations. The salary and job title for this opening will be based on the selected candidate’s qualifications and experience and may be outside this range. Join us and work with a cutting edge organization creating cutting edge technology. At Inscripta, we don’t just accept difference — we celebrate it, support it, and thrive on it for the benefit of our employees, our innovation, and our community. We are proud to be an equal opportunity workplace because the more inclusive we are as a company, the better our work will be. Inscripta is headquartered in Boulder, CO with offices in Pleasanton and San Diego, CA. This position is located in our Boulder, CO office location but may require travel to our Pleasanton, CA office as needed.

  • Engineering Technician

    Inscripta is developing the world’s first scalable platform for benchtop Digital Genome Engineering. The company’s advanced CRISPR-based platform, consisting of an instrument, reagents, and software, will offer a fully automated workflow that enables multiplexed, trackable editing of cells at an unprecedented scale. Inscripta’s goal is to empower scientists whose gene editing research is stifled by current technical and licensing limitations. By providing this unique platform and engaging in collaborative business practices, such as making its MAD7 CRISPR nuclease free for research purposes, the company enables scientists to realize a new era of biological discovery. Due to rapid growth Inscripta has an opening for an Engineering Technician located in Pleasanton, CA.

    Summary:
    We are looking for an experienced Engineering Technician who will significantly contribute to the development of our Digital Genome Engineering platforms. You will work with an extremely talented team who are used to moving quickly. This is an exciting opportunity to build the technology from the ground up.

    Responsibilities:
    • Build, service, and test electro-mechanical fluidic systems designed by Inscripta engineers.
    • Work with engineering team to execute test plans on instrument, collect data, perform analysis, and report and present the results.
    • Maintain accurate and complete data records in electronic form.
    • Assist root cause analysis on issues found during testing.
    • Design and execute mechanical, electrical, and full system tests on existing and newly developed systems.
    • Communicate effectively with a cross-functional team consisting of engineers and scientists.

    Requirements:
    • 3-5+ years of experience building & testing electro-mechanical equipment.
    • Programming experience: NET, C++, python or similar.
    • Mechanically minded individuals to identify and accurately report problems.
    • Strong debugging, troubleshooting, and root-cause analysis skills.
    • Organized and can keep track of assigned tasks and priorities, with minimal supervision.
    • Skilled with computers and Microsoft Office; especially Excel, windows filing system, and others.
    • Strong communication skills (verbal and written).
    • AS or BS engineering degree.
    • Experience using hand tools and multimeter.

    Bonus Qualifications:
    • Ability to read, revise, and make engineering drawings and electrical schematics.
    • 3D CAD experience (Solidworks).
    • Electronics design experience.
    • Mechanical fabrication experience.
    • Experience in a startup setting.

    Inscripta offers a competitive base salary, bonus plan, benefits package, 401k match, and an attractive equity program to all team members. Join us and work with a cutting edge organization creating cutting edge technology. At Inscripta, we don’t just accept difference — we celebrate it, support it, and thrive on it for the benefit of our employees, our innovation, and our community. We are proud to be an equal opportunity workplace because the more inclusive we are as a company, the better our work will be. Inscripta is headquartered in Boulder, CO with offices in Pleasanton and San Diego, CA. This position is located in our Pleasanton office location.

  • Field Applications Scientist – North America East

    Inscripta was founded in 2015 and recently launched the world’s first benchtop Digital Genome Engineering platform. The company is growing aggressively, investing in its leadership, team, and technology with a recent $150mm financing round led by Fidelity and TRowe price. The company’s advanced CRISPR-based platform, consisting of an instrument, reagents, and software, offers a fully automated workflow that enables multiplexed, trackable editing of cells at an unprecedented scale. Inscripta’s mission is to enable scientists to realize the full potential of biology. Due to rapid growth and recent commercialization, Inscripta has an opening for a Field Applications Scientist (FAS), North America East. This role can be based in or around any East Coast city near a major airport.

    We are looking for outstanding Field Applications Scientist to drive market adoption and ensure customer success using Inscripta’s Digital Genome Engineering platform. This individual will provide premier support for our instrumentation, consumables, software and assays. The FAS will leverage their experience in genome editing, next generation sequencing and NGS data analysis to match customer research goals to our platform’s capabilities, conduct training, project design and troubleshooting, and help drive the reorder cycle. They’ll also relay customer feedback to Field Sales, Applications, and Marketing to optimize the customer’s user experience.

    Responsibilities
    • Deliver exceptional pre/post-sales applications support; educate customers on the use of our technology and help them conduct novel genome engineering projects to maximize their research success.
    • Understand the customer’s research requirements to help them design, implement, analyze and interpret their experiments, thus building the scientific credibility of both the FAS and our technology.
    • Work with Field Sales representatives, supporting their efforts to identify, develop and close high-value sales opportunities to meet/exceed revenue targets for hardware and consumables.
    • Persuasively deliver technical, customer-facing seminars covering a variety of scientific research areas, applications, products and data related to Inscripta’s technology platform.
    • Coordinate with Sales, Applications Development, Marketing and Product Management to implement successful strategies that balance the needs of the customer, Sales, and internal departments.
    • Act as an internal customer advocate by communicating information between the customer, Sales, Marketing, Applications and other departments related to product feedback, competitive intelligence, market trends, and effectiveness of marketing, positioning, and field tactics.
    • Build, engage and leverage a network of early access and KOL customers to drive the awareness and reputation of our platform and deepen customer relationships with key scientific leaders.

    Requirements
    • Research and/or commercial experience in one or more of the following areas: CRISPR-based genome editing, next generation sequencing, synthetic biology, metabolic engineering and functional genomics.
    • Familiarity with/expertise using CRISPR design tools and/or next generation sequence analysis software.
    • Experience in the demonstration, installation, operation and troubleshooting of sophisticated, high-throughput instrument platforms. Previous field applications support experience is preferred.
    • Ph.D. in a relevant field with 2+ years’ experience (post-doc or industrial); Master’s degree with 5+ years’ experience and exceptional qualifications.
    • Experience in successful experimental design, interpretation, troubleshooting and optimization. Ability to develop solutions to complex problems that require innovation and collaboration.
    • Strong verbal, written and interpersonal communication skills to effectively deliver technical presentations, handle customer issues and work collaboratively to support the efforts of Field Sales.
    • Ability to learn quickly and work in a highly innovative, fast-paced startup environment, collaborating closely with other cross-functional and geographically distributed teams.
    • Avg. 30-40% overnight travel primarily in the eastern half of North America. This position will be based in or around any East Coast city near a major airport.

    Inscripta offers a competitive base salary, bonus plan, benefits package, 401k match and an attractive equity program to all team members. Join us and work with a cutting edge organization creating cutting edge technology. At Inscripta, we don’t just accept difference — we celebrate it, support it, and thrive on it for the benefit of our employees, our innovation, and our community. We are proud to be an equal opportunity workplace because the more inclusive we are as a company, the better our work will be. Inscripta is headquartered in Boulder, CO with offices in Pleasanton and San Diego, CA. This position can be based in or around any East Coast city near a major airport.

  • Senior Scientist

    Inscripta was founded in 2015 and recently launched the world’s first benchtop Digital Genome Engineering platform. The company is growing aggressively, investing in its leadership, team, and technology with a recent $150mm financing round led by Fidelity and TRowe price. The company’s advanced CRISPR-based platform, consisting of an instrument, reagents, and software, offers a fully automated workflow that enables multiplexed, trackable editing of cells at an unprecedented scale. Inscripta’s mission is to enable scientists to realize the full potential of biology. Due to rapid growth and recent commercialization, Inscripta has an opening for a Senior Scientist located in our Pleasanton, CA office.

    Summary
    Do you love tinkering with nucleic acids? Is protocol improvement an unshakeable habit? We are looking for a creative scientist who is passionate about building and commercializing the assays that drive CRISPR-based genome editing at Inscripta.

    Essential aspects of this position include: prolific innovation, superior experimental design & execution, and robust protocol development. The right candidate will enthusiastically leverage their experience, curiosity, and creativity to build industry-leading molecular biology and genetic-engineering tools in a highly innovative, team-oriented, and vibrant R&D environment.

    Responsibilities
    • Design and develop robust assays with simple, automation-compatible workflows.
    • Work collaboratively with biochemists, molecular biologists, bioinformaticians, and engineers to identify, build, and optimize the assays that propel genome engineering.
    • Execute complex, highly multiplexed experiments that accurately evaluate protocol improvements.
    • Conduct detailed data analyses, use bioinformatic pipelines, & provide data-driven recommendations.
    • Transfer new methodologies and assays from R&D to Systems-Integration and Manufacturing.
    • Provide clear and concise written and oral communications to colleagues and supervisors.

    Required Skills and Experience
    • Extensive experience with: NGS, PCR, qPCR, oligo design, and nucleic acid manipulation.
    • Demonstrated record of innovation developing molecular biology assays and techniques.
    • Proven ability to work collaboratively on cross-functional teams in a highly matrixed environment.
    • Exceptional data analysis skills combined with strong logical thinking.
    • Ability to learn quickly and willingness to work determinedly at a dynamic startup company.

    Desired Skills and Experience
    • Familiarity with at least one programming or scripting language such as R or Python.
    • Experience with genome engineering, cloning, and microbe & mammalian cell culture.

    Inscripta offers a competitive base salary, bonus plan, benefits package, 401k match and an attractive equity program to all team members. Join us and work with a cutting edge organization creating cutting edge technology. At Inscripta, we don’t just accept difference — we celebrate it, support it, and thrive on it for the benefit of our employees, our innovation, and our community. We are proud to be an equal opportunity workplace because the more inclusive we are as a company, the better our work will be. Inscripta is headquartered in Boulder, CO with offices in Pleasanton and San Diego, CA. This position is located in our Pleasanton, CA office location.

  • Director/ Senior Director, Mammalian Cell Biology

    Inscripta was founded in 2015 and recently launched the world’s first benchtop Digital Genome Engineering platform. The company is growing aggressively, investing in its leadership, team, and technology with a recent $150mm financing round led by Fidelity and TRowe price. The company’s advanced CRISPR-based platform, consisting of an instrument, reagents, and software, offers a fully automated workflow that enables multiplexed, trackable editing of cells at an unprecedented scale. Inscripta’s mission is to enable scientists to realize the full potential of biology. Due to rapid growth and recent commercialization, Inscripta has an opening for a Director/Sr. Director, Mammalian Cell Biology, located in Boulder, CO or Pleasanton, CA.

    Summary:
    Inscripta is looking for an experienced scientific and team leader for our Mammalian Cell Biology group to achieve innovative product development of Inscripta’s genome engineering reagents and platforms.

    Responsibilities:
    • Conceive, propose, prioritize, and drive scientific strategies around innovative cell biological approaches to develop and deliver CRISPR-based reagent technologies that support Inscripta’s gene editing products.
    • Direct and mentor a team of 10-15 cell biological scientists and research associates designing, screening and optimizing genome editing reagents for successful product integration.
    • Provide vision and structure to the organization and operation of a high-functioning team in a matrixed, product development environment focused on delivering high quality results in accordance with requirements across multiple projects and products.
    • Provide teaching / training and implement rigorous and robust experimental design and quality control metrics to support generation of the highest degree of quality and reproducible data.
    • Direct cross-functional projects across computational science, biology, chemistry, and engineers in a matrixed product development environment.
    • Provide subject matter expertise on existing and developing genome editing science and technologies, as well as screening and measurement methodologies, with a goal of consistently driving innovation and improvements to Inscripta’s genome editing chemistries and platforms.
    • As opportunities arise internally, take on a role as core team member to achieve product development objectives in a matrixed environment, in accordance with corporate goals.
    • Work with core team and senior leadership to ensure goals are aligned with strategic direction.

    Requirements:
    • Ph.D. in genetics, cell biology or related scientific field and approximately 7 to 10 years of relevant industry experience, including 3-5 years’ experience leading and mentoring teams of 5 or more scientists and research associates; strong preference for experience in start-up organizations.
    If this seems like your dream job, but you’re not sure if you qualify, please apply anyway!
    • Track record of innovation and scientific creativity in developing solutions for genome engineering reagent system and integrated performance requirements in life sciences / biotechnology industry.
    • Experience successfully managing complex projects and adjusting to changing priorities in a product development environment, including developing and executing focused project plans.
    • Openness and capability to “lead from the bench” when required.
    • Maturity and accountability to lead and deliver on commitments in a matrixed organization.
    • Ability to serve as subject matter expert within the fields of DNA repair, gene editing, genetics, cell biology, and ideally, NGS and related genome editing read out technologies.
    • Experience positioning projects and individual contributors for success through team member goal setting, continual assessment, feedback and coaching, as well as technical direction and task prioritization.
    • Ability to organize, communicate, and present complex technical data, progress and challenges to cross-disciplinary teams, senior management and key stakeholders.
    • Outstanding interpersonal, scientific leadership and collaboration skills, including self-awareness and ability to manage complex dynamics.

    Inscripta offers a competitive base salary, bonus plan, benefits package, 401k match and an attractive equity program to all team members. Join us and work with a cutting edge organization creating cutting edge technology. At Inscripta, we don’t just accept difference — we celebrate it, support it, and thrive on it for the benefit of our employees, our innovation, and our community. We are proud to be an equal opportunity workplace because the more inclusive we are as a company, the better our work will be. Inscripta is headquartered in Boulder, CO with offices in Pleasanton and San Diego, CA. The role can work out of either location, but Pleasanton workers will travel regularly to Boulder, CO.

  • Scientist

    Inscripta was founded in 2015 and recently launched the world’s first benchtop Digital Genome Engineering platform. The company is growing aggressively, investing in its leadership, team, and technology with a recent $150mm financing round led by Fidelity and TRowe price. The company’s advanced CRISPR-based platform, consisting of an instrument, reagents, and software, offers a fully automated workflow that enables multiplexed, trackable editing of cells at an unprecedented scale. Inscripta’s mission is to enable scientists to realize the full potential of biology. Due to rapid growth and recent commercialization, Inscripta has an opening for a Scientist located in Pleasanton, CA.

    Summary
    Inscripta is searching for a Scientist with expertise in mammalian cell management to join our product development team. The ideal candidate will have deep technical knowledge and hands on experience in the culturing, characterization, and manipulation of mammalian cells. In this role, they will work on a multi-disciplinary team to assess reagent and system performance of Inscripta’s digital genome engineering platforms, as well as be responsible for implementing methods to QC cell viability, health and other characteristics critical for the compatibility of our technology with customer applications. They will also thrive in a data-driven environment and work closely with a world class team of life scientists, engineers, and computational data scientists.

    Responsibilities
    • Independently design, execute, and analyze experiments to assess performance of product-facing reagent chemistry.
    • Optimize and deploy protocols for mammalian cell-based workflows.
    • Develop assays to QC cell viability, health, and other critical product relevant cell characteristics.
    • Implement and maintain human cell culture, characterization, and banking standards.
    • Maintain policies and procedures related to biosafety.
    • Effectively direct, organize, and manage workload to execute complex experiments according to an aggressive product development schedule.
    • Present clear and concise written and oral communications to colleagues and supervisors, participate in technical meetings, and provide recommendations based on technical results.

    Requirements
    • Ph.D in cell biology, immunology, biochemistry, developmental biology, molecular biology, or a related discipline.
    • Demonstrated experience in the derivation, culture, and characterization of mammalian cells. Particular consideration will be given to candidates with demonstrated experience working with primary cells (e.g. human immune cells, human pluripotent stem cells, keratinocytes, hepatocytes, and/or neurons).
    • Experience developing assays to characterize human cells, including multicolor flow cytometry and qPCR.
    • Ability to work both independently, within matrixed project teams, and in a dynamic environment where priorities can shift with data-driven decisions.
    • Excellent written and oral communication skills.
    • Track record of attention to detail and focus on standardization.

    Inscripta offers a competitive base salary, bonus plan, benefits package, 401k match and an attractive equity program to all team members. Base Salary Range: $90,000 to $100,000 per year. Base salary range provided per current averages and expectations. The salary and job title for this opening will be based on the selected candidate’s qualifications and experience and may be outside this range. Join us and work with a cutting edge organization creating cutting edge technology. At Inscripta we don’t just accept difference — we celebrate it, support it, and thrive on it for the benefit of our employees, our innovation, and our community. We are proud to be an equal opportunity workplace because the more inclusive we are as a company, the better our work will be. Inscripta is headquartered in Boulder, CO with offices in Pleasanton and San Diego, CA. This position is located in our Pleasanton office location.

  • Staff Scientist/ Senior Scientist

    Inscripta was founded in 2015 and recently launched the world’s first benchtop Digital Genome Engineering platform. The company is growing aggressively, investing in its leadership, team, and technology with a recent $150mm financing round led by Fidelity and TRowe price. The company’s advanced CRISPR-based platform, consisting of an instrument, reagents, and software, offers a fully automated workflow that enables multiplexed, trackable editing of cells at an unprecedented scale. Inscripta’s mission is to enable scientists to realize the full potential of biology. Due to rapid growth and recent commercialization, Inscripta has an opening for a Staff/Senior Scientist located in Pleasanton, CA.

    Summary
    Inscripta is searching for a highly talented Staff/Senior Scientist to join our Biochemistry group. The ideal candidate will have demonstrated experience in assay development, a strong analytical background in biochemistry, proficiency with a variety of molecular read-out tools, and the ability to design & execute complex experiments according to a project schedule. In this role, they will be a key member of our multi-disciplinary team and lead efforts to stand up assays to quantitatively assess system performance of Inscripta’s mammalian digital genome engineering platform. They will also thrive in a data-driven, dynamic environment and work closely with a world class team of life scientists, engineers, and computational data scientists.

    Responsibilities
    • Lead the design and development of custom assays aimed at reagent and edit detection.
    • Lead the design and verification of custom assays to quantify the presence, function, and/or kinetics of biomolecules and complexes formed from them (e.g. protein/DNA complexes), in vivo or ex vivo, to enable metrics-driven read-outs of system performance.
    • Leverage both computational and empirical methods for experiment design and data analysis.
    • Verify assay performance using statistically rigorous experimental design with appropriate selection of sample preparation and measurement controls to establish assay sensitivity and precision.
    • Collaborate with life scientists, engineers and computational data scientists to define and develop measurement tool specifications, metrics and data analysis methods.
    • Effectively direct, organize, and manage workload to execute complex experiments according to an aggressive product development schedule.
    • Present clear and concise written and oral communications to colleagues and supervisors, participate in technical meetings, and provide recommendations based on technical results.

    Requirements
    • Ph.D. in Biochemistry, Molecular Biology, Chemistry, or a related discipline
    • A minimum of 2 years of experience developing robust biochemical, biophysical, and/or biomolecular assays. For the Staff Scientist level, candidates would need to have at least six years of relevant experience. Salary will be based on experience.
    • Proficiency in a breadth of biochemistry/molecular biology techniques – including DNA/RNA purification, protein purification, ddPCR/qPCR, RT-qPCR, Sanger/NGS sequencing, primer/probe design, and protein labeling techniques (e.g. immunohistochemistry).
    • Ability to work both independently, within matrixed project teams, and in a dynamic environment where priorities can shift with data-driven decisions.
    • Excellent written and oral communication skills.
    • Exceptional data analysis skills combined with strong analytical thinking.
    • Track record of creativity and problem-solving.

    Inscripta offers a competitive base salary, bonus plan, benefits package, 401k match and an attractive equity program to all team members. Base Salary Range: $110,000 to $150,000 per year. Base salary range provided per current averages and expectations. The salary and job title for this opening will be based on the selected candidate’s qualifications and experience and may be outside this range. Join us and work with a cutting edge organization creating cutting edge technology. At Inscripta, we don’t just accept difference — we celebrate it, support it, and thrive on it for the benefit of our employees, our innovation, and our community. We are proud to be an equal opportunity workplace because the more inclusive we are as a company, the better our work will be. Inscripta is headquartered in Boulder, CO with offices in Pleasanton and San Diego, CA. This position is located in our Pleasanton office location.

  • Staff Systems Engineer/ Senior Staff Systems Engineer

    Inscripta was founded in 2015 and recently launched the world’s first benchtop Digital Genome Engineering platform. The company is growing aggressively, investing in its leadership, team, and technology with a recent $150mm financing round led by Fidelity and T. Rowe Price. The company’s advanced CRISPR-based platform, consisting of an instrument, reagents, and software, offers a fully automated workflow that enables multiplexed, trackable editing of cells at an unprecedented scale. Inscripta’s mission is to enable scientists to realize the full potential of biology. Due to rapid growth and recent commercialization, Inscripta has an opening for a Staff Systems Engineer /Sr. Staff Systems Engineer located in Pleasanton, CA or Boulder, CO.

    Summary:
    The Staff Systems Engineer /Sr. Staff Systems Engineer who will use a multi-disciplinary approach to define architecture and sub-system requirements for a new, industry leading gene editing platform. These disciplines include biology, reagents, and instrument consumables as well as the associated software and hardware. This is an opportunity to drive the definition and implementation of system engineering best practices.

    Responsibilities:
    • Provide project level leadership and work with SMEs to define, design, develop, characterize, and validate platforms at the interface of electromechanical systems and biology.
    • Analyze, design and test biological systems that include fluidics, optics, sensors, machined and molded hardware and consumable hardware components.
    • Collaborate with a diverse cross-functional team (biologists, analytical scientists, engineers, etc.) to define and develop robust integrated instrumentation, consumables and software.
    • Proactive development of in-depth knowledge of the product technology and a good working knowledge of the associated biological processes.
    • Model fluid flows, biological flows, temperatures, reagent concentrations, etc. to construct a complete system model, especially to spec submodule interfaces and to identify critical parameters and determine best design approach.
    • Model interfaces between instrument submodules across hardware, software, and consumables to identify critical parameters and determine best design approach.
    • Design and perform tests to ensure specifications are met; collect data to help troubleshoot and evolve designs.

    Requirements:
    • B.S., M.S., or PhD in Systems, Mechanical, or Electrical Engineering or related engineering discipline.
    • 7+ years of system design experience. Taken at least one commercial instrument from concept to shipment.
    • Experience with life science instrumentation.
    • Strong interdepartmental communication skills.

    Desired:
    • Taken commercial instrument(s) involving biology or biochemistry from concept to shipment.
    • Experience in instrumentation and consumables development.
    • Experience with engineering documentation and control practices.
    • Proven history of systematic troubleshooting and innovative problem solving.
    • Experience with aseptic biological reagent and cell handling methodologies and design of engineering systems to support them (e.g., aseptic fittings and sterile equipment design).
    • Experience with systems modeling (Matlab, COMSOL, or similar).
    • Experience with requirements analysis, FMEA, reliability and compliance testing.
    • Understanding of statistical methods and Design of Experiments.

    Inscripta offers a competitive base salary, bonus plan, benefits package, 401k match and an attractive equity program to all team members. Base Salary Range: $150k – $200k per year. Base salary range provided per current averages and expectations. The salary and job title for this opening will be based on the selected candidate’s qualifications and experience and may be outside this range. Join us and work with a cutting edge organization creating cutting edge technology. At Inscripta, we don’t just accept difference — we celebrate it, support it, and thrive on it for the benefit of our employees, our innovation, and our community. We are proud to be an equal opportunity workplace because the more inclusive we are as a company, the better our work will be. Inscripta is headquartered in Boulder, CO with offices in Pleasanton and San Diego, CA. This position can be at either our Boulder or Pleasanton location.

  • Field Applications Scientist – North America West

    Inscripta was founded in 2015 and recently launched the world’s first benchtop Digital Genome Engineering platform. The company is growing aggressively, investing in its leadership, team, and technology with a recent $150mm financing round led by Fidelity and TRowe price. The company’s advanced CRISPR-based platform, consisting of an instrument, reagents, and software, offers a fully automated workflow that enables multiplexed, trackable editing of cells at an unprecedented scale. Inscripta’s mission is to enable scientists to realize the full potential of biology. Due to rapid growth and recent commercialization, Inscripta has an opening for a Field Applications Scientist (FAS), North America West. This role can be based in or around the San Francisco area or any West Coast city near a major airport.

    We are looking for outstanding Field Applications Scientist to drive market adoption and ensure customer success using Inscripta’s Digital Genome Engineering platform. This individual will provide premier support for our instrumentation, consumables, software and assays. The FAS will leverage their experience in genome editing, next generation sequencing and NGS data analysis to match customer research goals to our platform’s capabilities, conduct training, project design and troubleshooting, and help drive the reorder cycle. They’ll also relay customer feedback to Field Sales, Applications, and Marketing to optimize the customer’s user experience.

    Responsibilities:
    • Deliver exceptional pre/post-sales applications support; educate customers on the use of our technology and help them conduct novel genome engineering projects to maximize their research success.
    • Understand the customer’s research requirements to help them design, implement, analyze and interpret their experiments, thus building the scientific credibility of both the FAS and our technology.
    • Work with Field Sales representatives, supporting their efforts to identify, develop and close high-value sales opportunities to meet/exceed revenue targets for hardware and consumables.
    • Persuasively deliver technical, customer-facing seminars covering a variety of scientific research areas, applications, products and data related to Inscripta’s technology platform.
    • Coordinate with Sales, Applications Development, Marketing and Product Management to implement successful strategies that balance the needs of the customer, Sales, and internal departments.
    • Act as an internal customer advocate by communicating information between the customer, Sales, Marketing, Applications and other departments related to product feedback, competitive intelligence, market trends, and effectiveness of marketing, positioning, and field tactics.
    • Build, engage and leverage a network of early access and KOL customers to drive the awareness and reputation of our platform and deepen customer relationships with key scientific leaders.

    Requirements:
    • Research and/or commercial experience in one or more of the following areas: CRISPR-based genome editing, next generation sequencing, synthetic biology, metabolic engineering and functional genomics.
    • Familiarity with/expertise using CRISPR design tools and/or next generation sequence analysis software.
    • Experience in the demonstration, installation, operation and troubleshooting of sophisticated, high-throughput instrument platforms. Previous field applications support experience is preferred.
    • Ph.D. in a relevant field with 2+ years’ experience (post-doc or industrial); Master’s degree with 5+ years’ experience and exceptional qualifications.
    • Experience in successful experimental design, interpretation, troubleshooting and optimization. Ability to develop solutions to complex problems that require innovation and collaboration.
    • Strong verbal, written and interpersonal communication skills to effectively deliver technical presentations, handle customer issues and work collaboratively to support the efforts of Field Sales.
    • Ability to learn quickly and work in a highly innovative, fast-paced startup environment, collaborating closely with other cross-functional and geographically distributed teams.
    • Avg. 30-40% overnight travel in the Western half of North America. This position will be based in or around the San Francisco area or any West Coast city near a major airport.

    Inscripta offers a competitive base salary, bonus plan, benefits package, 401k match and an attractive equity program to all team members. Join us and work with a cutting edge organization creating cutting edge technology. At Inscripta, we don’t just accept difference — we celebrate it, support it, and thrive on it for the benefit of our employees, our innovation, and our community. We are proud to be an equal opportunity workplace because the more inclusive we are as a company, the better our work will be. Inscripta is headquartered in Boulder, CO with offices in Pleasanton and San Diego, CA. This position can be based in or around the San Francisco area or any West Coast city near a major airport.

  • Scientific Project Manager

    Inscripta was founded in 2015 and recently launched the world’s first benchtop Digital Genome Engineering platform. The company is growing aggressively, investing in its leadership, team, and technology with a recent $150mm financing round led by Fidelity and T. Rowe Price. The company’s advanced CRISPR-based platform, consisting of an instrument, reagents, and software, offers a fully automated workflow that enables multiplexed, trackable editing of cells at an unprecedented scale. Inscripta’s mission is to enable scientists to realize the full potential of biology. Due to rapid growth and recent commercialization, Inscripta has an opening for a Scientific Project Manager located in Boulder, CO, Pleasanton, CA, or San Diego, CA.

    Summary:
    We are looking for a self-driven and talented candidate to join our Program Management team to work with cross-functional, technical teams developing new products. Partnering closely with the project lead, this individual will make sure that priorities, risks, resources, and schedules are established, managed, and reported across the project.

    Responsibilities:
    • Serve as project manager for the development of instruments and consumables at the interface of biology, biochemistry, fluidic, electrical, and mechanical disciplines.
    • With the technical lead of the project, help define and prioritize the team towards retiring technical risks and project goals.
    • Work across commercial teams, technical teams, and executives to manage the project portfolio.
    • Develop and track project plans, schedules, and risks across a multidisciplinary team and diversity of stakeholders.
    • Identify and resolve issues with interdependent timelines, priorities, and resourcing.
    • Present project and platform progress updates to leadership teams against project expectations.
    • Drive improvements in Inscripta’s product development processes and practices to meet company needs.

    Requirements:
    • BS, MS, or PhD in biology, biochemistry, chemistry, genetics, or engineering.
    • At least 6 years of experience in development of new instruments or consumables/reagents products in biotech or life sciences.
    • At least 2 years in a project management role is required. PMP certification desired.
    • Demonstrated abilities to organize, plan, prioritize, and track complex, multidisciplinary development projects required.
    • Strong interdepartmental communication skills (oral, listening, written, presentation) are required
    • Ability to be adaptable in a fast-paced environment.
    • Experience taking at least 1 platform product combining electromechanical instrumentation, fluidics, and software through a product development process (concept through full-scale operation) desired.

    Inscripta offers a competitive base salary, bonus plan, benefits package, 401k match and an attractive equity program to all team members. Join us and work with a cutting edge organization creating cutting edge technology. At Inscripta, we don’t just accept difference — we celebrate it, support it, and thrive on it for the benefit of our employees, our innovation, and our community. We are proud to be an equal opportunity workplace because the more inclusive we are as a company, the better our work will be. Inscripta is headquartered in Boulder, CO with offices in Pleasanton and San Diego, CA. This position is located in our Boulder, CO, Pleasanton, CA, or San Diego, CA location.

  • Director/ Senior Director, Mammalian Cell Biology

    Inscripta was founded in 2015 and recently launched the world’s first benchtop Digital Genome Engineering platform. The company is growing aggressively, investing in its leadership, team, and technology with a recent $150mm financing round led by Fidelity and TRowe price. The company’s advanced CRISPR-based platform, consisting of an instrument, reagents, and software, offers a fully automated workflow that enables multiplexed, trackable editing of cells at an unprecedented scale. Inscripta’s mission is to enable scientists to realize the full potential of biology. Due to rapid growth and recent commercialization, Inscripta has an opening for a Director/Sr. Director, Mammalian Cell Biology, located in Boulder, CO or Pleasanton, CA.

    Inscripta is looking for an experienced scientific and team leader for our Mammalian Cell Biology group to achieve innovative product development of Inscripta’s genome engineering reagents and platforms.

    Responsibilities:
    • Conceive, propose, prioritize, and drive scientific strategies around innovative cell biological approaches to develop and deliver CRISPR-based reagent technologies that support Inscripta’s gene editing products.
    • Direct and mentor a team of 10-15 cell biological scientists and research associates designing, screening and optimizing genome editing reagents for successful product integration.
    • Provide vision and structure to the organization and operation of a high-functioning team in a matrixed, product development environment focused on delivering high quality results in accordance with requirements across multiple projects and products.
    • Provide teaching / training and implement rigorous and robust experimental design and quality control metrics to support generation of the highest degree of quality and reproducible data.
    • Direct cross-functional projects across computational science, biology, chemistry, and engineers in a matrixed product development environment.
    • Provide subject matter expertise on existing and developing genome editing science and technologies, as well as screening and measurement methodologies, with a goal of consistently driving innovation and improvements to Inscripta’s genome editing chemistries and platforms.
    • As opportunities arise internally, take on a role as core team member to achieve product development objectives in a matrixed environment, in accordance with corporate goals.
    • Work with core team and senior leadership to ensure goals are aligned with strategic direction.

    Requirements:
    • Ph.D. in genetics, cell biology or related scientific field and at least 10 years of relevant industry experience with 5+ years’ experience leading and mentoring teams of 5 or more scientists and research associates; strong preference for experience in start-up organizations.
    • Track record of innovation and scientific creativity in developing solutions for genome engineering reagent system and integrated performance requirements in life sciences / biotechnology industry.
    • Experience successfully managing complex projects and adjusting to changing priorities in a product development environment, including developing and executing focused project plans.
    • Openness and capability to “lead from the bench” when required.
    • Maturity and accountability to lead and deliver on commitments in a matrixed organization.
    • Ability to serve as subject matter expert within the fields of DNA repair, gene editing, genetics, cell biology, and ideally, NGS and related genome editing read out technologies.
    • Experience positioning projects and individual contributors for success through team member goal setting, continual assessment, feedback and coaching, as well as technical direction and task prioritization.
    • Ability to organize, communicate, and present complex technical data, progress and challenges to cross-disciplinary teams, senior management and key stakeholders.
    • Outstanding interpersonal, scientific leadership and collaboration skills, including self-awareness and ability to manage complex dynamics.

    Inscripta offers a competitive base salary, bonus plan, benefits package, 401k match, and an attractive equity program to all team members. Join us and work with a cutting edge organization creating cutting edge technology. At Inscripta we don’t just accept difference — we celebrate it, support it, and thrive on it for the benefit of our employees, our innovation, and our community. We are proud to be an equal opportunity workplace because the more inclusive we are as a company, the better our work will be. Inscripta is headquartered in Boulder, CO with offices in Pleasanton and San Diego, CA. The role can work out of either our Pleasanton, CA or Boulder, CO, but Pleasanton workers will travel regularly to Boulder, CO.

  • Synthetic Biology Scientist

    ResVita Bio is an early-stage synthetic biology start-up spun out of UC Berkeley. We seek to build genetically engineered skin probiotics to treat chronic skin diseases. We have developed a platform for controlled colonization of the skin with engineered therapeutic bacteria and are applying this to multiple disease areas. We have submitted an application to the FDA for the Rare Pediatric Disease Designation for Netherton Syndrome, a devastating skin condition that most severely affects children, and are actively progressing programs in atopic dermatitis and psoriasis.

    ResVita Bio is hiring a scientist who is eager to push the boundaries of synthetic biology and metabolic engineering to develop the next generation of bio-therapies to treat deadly and destructive skin diseases. This is an exciting, multi-disciplinary position branching the fields of immunology, dermatology, synthetic biology and metabolic engineering. The scientist will work closely with our CEO to advance our platform to develop and test therapeutic strains for the treatment of skin diseases. The ideal candidate will have experience in murine models, but prior experience with microbial communities is not required.

    As a small start-up, your creativity, values, and managerial skills will help shape ResVita Bio’s path as well as its culture. At ResVita Bio, we believe a diverse workforce will help us achieve our mission to meaningfully change the outcome of many human diseases. Come and play an important role in the development and commercialization of a technology at the forefront of biology and engineering.

    Responsibilities
    Design and construct DNA expression and integration cassettes, building and screening combinatorial strain/enzyme libraries, and analyze and improve of strain performance
    Develop new genetic tools and improve media engineering to improve in vivo strain performance
    Directly test designed strains in skin-damaged murine models
    Collaborate with immunologists to design and interpret animal experiments
    Contribute to the generation and documentation of intellectual property

    Key Qualifications
    PhD in bioengineering, chemical engineering, molecular biology, or biochemistry or a related discipline
    Proficient with microbial genetic engineering and molecular biology bench work
    Direct experience in synthetic biology or metabolic engineering projects
    Ideally, the candidate has some experience with murine models
    Must be able to work independently and have strong organizational and planning skills
    Eagerness to work collaboratively on a team of experts while adapting to the fast-paced needs of an early-stage startup

  • Systems Integration Summer Intern

    Inscripta was founded in 2015 and recently launched the world’s first benchtop Digital Genome Engineering platform. The company’s advanced CRISPR-based platform, consisting of an instrument, reagents, and software, will offer a fully automated workflow that enables multiplexed, trackable editing of cells at an unprecedented scale. Inscripta’s goal is to empower scientists whose gene editing research is stifled by current technical and licensing limitations. By providing this unique platform and engaging in collaborative business practices, such as making its MAD7 CRISPR nuclease free for research purposes, the company enables scientists to realize a new era of biological discovery. Due to rapid growth Inscripta has an opening for a Systems Integration Summer Intern located at our Pleasanton, CA office.

    Summary:
    This paid internship will last a minimum of 10 weeks throughout the summer and will have full-time hours, 40 hours per week, Monday through Friday.

    The Systems Integration team is part of R&D and works on testing and troubleshooting new instruments and automating CRISPR editing workflows.

    This position is hands on, lab bench oriented and will provide the applicant many opportunities to learn new and standard molecular and cell biology lab techniques. In addition, the applicant will learn how to operate and troubleshoot our gene editing instruments. We are looking for exceptional candidates with a passion for science, problem solving, and contributing to the development of new technologies and products.

    Responsibilities:
    The candidate will contribute to the following projects and efforts in the Systems Integration team:
    • Developing next generation, high throughput, CRISPR editing workflows on our instruments. This would involve iPSC cell culture, cell processing, and testing/developing fluidic devices on Inscripta instruments.
    • Creating new SOPs or other protocols for calibrating and/or operating Inscripta instruments.
    • Regular lab maintenance and setting up CRISPR editing runs on our instruments.
    • Contribute to data analysis efforts of instrument data and present work at regular team meetings.

    Requirements:
    • Open to M.S., PhD or Bachelor’s students pursuing a degree in biotechnology, molecular biology, biochemistry, chemistry, or related field.
    • Experience with basic lab techniques including pipetting, aseptic technique, mammalian cell culture, and basic lab equipment.
    • Experience with data collection and data analysis. Experience with data analysis software such as Matlab or JMP is a plus.
    • Proficiency with Microsoft Excel, Powerpoint or similar programs.
    • Detail oriented, with a commitment to keep thorough accurate lab records.

    Inscripta offers a competitive hourly rate for interns. Join us and work with a great team of people developing the world’s first scalable platform for benchtop Digital Genome Engineering. At Inscripta, we don’t just accept difference — we celebrate it, support it, and thrive on it for the benefit of our employees, our innovation, and our community. We are proud to be an equal opportunity workplace because the more inclusive we are as a company, the better our work will be. Inscripta is headquartered in Boulder, CO with offices in Pleasanton and San Diego, CA. This position is located in our Pleasanton, CA office.

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