Job Board

  • Postdoctoral Associate, Yeast Synthetic Biology

    POSTDOCTORAL ASSOCIATE, Biological Engineering-Synthetic Biology Center-Weiss Lab, to join an interdisciplinary academic research lab that seeks to create integrated biological systems capable of autonomously performing useful tasks and to elucidate the design principles underlying the engineering of complex cellular and tissue phenotypes. Will pursue research in the area of yeast synthetic biology, bioreactor design, genetic circuit design, and assay of metabolic products; and work with a team with researchers, a principal investigator, and lab manager on metabolic engineering of yeast, including implementation of genetic circuits that sense cell state and implement feedback control (e.g., analog and digital logic functions) that result in precision control of transgenic metabolic products in one or more yeast strains. Responsibilities include designing genetic circuits (e.g., molecular cloning, yeast cell culture, DNA transfection); optimizing bioreactor conditions; designing assays; collecting data using state-of-the art analytical techniques, including mass spectrometry, flow cytometry, RT-qPCR, next-generation sequencing, and other analytic technologies; data analysis; communicating results–verbally and in writing–to team members; drafting IP disclosures; making presentations to the scientific community through talks and publications; and other tasks as needed.

    Job Requirements
    REQUIRED: Ph.D. in biological sciences, computer science, engineering, physics, math, or related field; experience in at least one of the following–yeast cell culture, large scale DNA assembly and characterization, genetic recombination technology, next-generation sequencing, computational methods and tools for analysis, and statistics; biological experience in molecular biology, protein engineering, immunology, and/or cell biology; ability to prioritize, perform multiple tasks, and execute detailed technical protocols meticulously; strong organizational, analytical, problem-solving, and documentation skills; and ability to collaborate and on individual projects in a dynamic, multidisciplinary, team-oriented setting. Job #20497

    Please apply online for this position (Job #20497) at https://careers.peopleclick.com/careerscp/client_mit/external/jobDetails/jobDetail.html?jobPostId=22459&localeCode=en-us

  • Professor (all ranks) in Bioprocessing and Biomaterials

    Arizona State University
    Ira A. Fulton Schools of Engineering
    School for Engineering of Matter, Transport and Energy

    Professor (all ranks) in Bioprocessing and Biomaterials
    Location: Arizona State University – Tempe Campus

    The Ira A. Fulton Schools of Engineering at Arizona State University (ASU) and the School for Engineering of Matter, Transport and Energy seek applicants for a tenure-track or tenured faculty position in the areas of Bioprocessing and Biomaterials. The School for Engineering of Matter, Transport and Energy, one of the seven Fulton Schools, houses a vibrant research community of biomaterials, and biomolecular and biological engineering (Learn more at https://research.engineering.asu.edu/). We seek applicants who complement our abilities in these areas to solve grand challenges as part of a community of experts. Particular areas of interest include, but are not limited to, upstream or downstream bioprocessing of biomolecules, biopharmaceuticals, biomaterials, cells, and/or tissues; vaccine engineering and biomanufacturing; computational and data sciences in bioprocessing and biomaterials; additive biomanufacturing; manufacturing in nanobiotechnology; and biomaterials for biomanufacturing.

    We seek applicants who will contribute to our academic programs, promote transdisciplinary teaching and research, and help the University to achieve its aspirations, including enabling student success, transforming society, valuing entrepreneurship, and conducting use-inspired research. Faculty members in the Fulton Schools are expected to develop an internationally recognized and externally funded research program, adopt effective pedagogical practices in the development and delivery of graduate and undergraduate courses, advise both undergraduate and graduate student research and projects and undertake service activities.

    This search is part of ASU’s engagement with the Arizona’s New Economy Initiative (NEI), a bold effort to ensure that Arizona leads the new economy that will rely on engineering, computing and technology to drive sustainable growth, resilience and opportunities for all. NEI investments in the Fulton Schools of Engineering will grow our world class faculty to accelerate research outcomes and to broaden student access to our programs; will establish Science and Technology Centers to foster the growth of new economy Industries; and will expand experiential learning and workforce training opportunities.

    Appointment will be at the assistant, associate, or full professor rank commensurate with the candidate’s experience and accomplishments, beginning August 2022. Although the tenure home may be in any of the Ira A. Fulton Schools of Engineering, the School for Engineering of Matter, Transport and Energy is currently the most involved in the interest of this research.

    Qualifications
    Required qualifications:
    • Earned doctorate in chemical engineering, bioengineering or related discipline by the time of appointment
    • Evidence of excellence in research, as appropriate to the candidate’s rank
    • Evidence of excellence in teaching, as appropriate to the candidate’s rank

    Desired qualifications:
    • Demonstrated commitment to a collaborative, transdisciplinary approach to research and teaching
    • Ability to engage in well-established research initiatives with numerous health care providers within the Phoenix area
    Application Instructions
    Review of applications will begin December 29, 2021. Applications will continue to be accepted on a rolling basis for a reserve pool. Applications in the reserve pool may then be reviewed in the order in which they were received until the position is filled. To apply, visit https://hiring.engineering.asu.edu/ and select “apply now” next to the corresponding position.  Candidates will be asked to create or use an existing Interfolio Dossier to submit the following:

    • Cover letter
    • Curriculum Vitae
    • Statement describing research interests (two pages maximum)
    • Statement describing teaching interests and philosophy (two pages maximum)
    • Statement describing commitment and approaches to advance Diversity, Equity, Inclusion and Belonging*
    • Contact information for three references

    *The ASU Charter states, “ASU is a comprehensive public research university, measured not by whom it excludes, but by whom it includes and how they succeed; advancing research and discovery of public value; and assuming fundamental responsibility for the economic, social, cultural and overall health of the communities it serves.” The Fulton Schools of Engineering are dedicated to continuous innovation, student success, faculty excellence, and cultivation of an environment that is diverse, equitable, inclusive and promotes belonging. The diversity statement provides applicants an opportunity to demonstrate their past and current activities in promoting diversity, equity, inclusion and belonging and how future activities will align with upholding the ASU Charter. All individuals who can strengthen the diversity of our academic community are encouraged to apply.

    For additional information regarding position specifics, please contact the search committee chair, Professor Brent Nannenga via email at [email protected]

    Equal Employment Opportunity Statement
    A background check is required for employment. Arizona State University is a VEVRAA Federal Contractor and an Equal Opportunity/Affirmative Action Employer. All qualified applicants will be considered without regard to race, color, sex, religion, national origin, disability, protected veteran status, or any other basis protected by law. (See https://www.asu.edu/aad/manuals/acd/acd401.html and https://www.asu.edu/titleIX/.)

    In compliance with federal law, ASU prepares an annual report on campus security and fire safety programs and resources.  ASU’s Annual Security and Fire Safety Report is available online at https://www.asu.edu/police/PDFs/ASU-Clery-Report.pdf.  You may request a hard copy of the report by contacting the ASU Police Department at 480-965-3456.

    To Apply, visit:
    https://apptrkr.com/2643467

  • Government Grants Finance Lead

    Company Overview

    Mission-driven LanzaTech is a revolutionary solution to climate change, capturing pollution to clean our skies and oceans and create new high value products for a sustainable future. LanzaTech captures pollution to make fuels and chemicals, including sustainable jet fuel and products you use every day. The technology is like retrofitting a brewery onto an emission source like a steel mill or a landfill site, but instead of using sugars and yeast to make beer, pollution is converted by biology to fuels and chemicals! Imagine a day when your plane is powered by recycled emissions, when your yoga pants started life as pollution from a steel mill. This future is possible using LanzaTech technology.

    • 2021 Biofuels Digest #1 Hottest Company in Renewable Fuels, Chemicals & Biomaterials
    • 2020 Biofuels Digest #3 Best Company to work for in the Advanced Bioeconomy
    • 2020 Fast Company World Changing Company
    • 2020 CNBC #43 on Top 50 Disrupter Companies list
    • 2019 Chicago Innovation Awards Winner
    • 2019 Fortune Magazine – Change the World – Companies to watch
    • 2019 Kirkpatrick Chemical Engineering Achievement Award

    LanzaTech is committed to Diversity, Equity & Inclusion as part of our mission, culture & core values
    This position is open to candidates authorized to work in the United States on a full-time basis for any employer. LanzaTech is an Equal Employment Opportunity employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, gender, sexual orientation, gender identity or expression, national origin, age, genetic information, disability, or veteran status.

    About the role

    This position reports to the Vice President of Finance and is responsible for all grant-related accounting and finance-related activities. This person will also provide oversight and monitor grant expenditures, communicate findings, and guide various teams on federal awards compliance, policies and procedures.

    Key duties

    Assist with grant budget proposals and modifications
    Monitor and report grant expenditures, sub-awards, cost-share requirements
    Review expense and revenue transactions for accuracy
    Prepare and submit progress billing, monthly revenue and expense accruals; update schedule of expenditures and other periodic grant-related reports
    Assist with Single Audits; review and update internal direct and indirect billable rates
    Ensure internal controls, federal requirements, and subrecipient monitoring policies are followed
    Ensure expenditures are properly documented, allowable, and within scope of grant
    Assist with monthly financial close activities

    Required Qualifications

    BA/BS in Accounting, Business, or related field.
    Strong knowledge of generally accepted accounting principles
    Experience and familiarity with government grant management and compliance procedures
    High attention to detail and accuracy
    Excellent skills with Microsoft Office
    Strong verbal and written communication skills
    Strong interpersonal and customer service skills required
    Ability to multi-task in fast-paced setting, you will be asked to make judgement calls about prioritization

  • Research Technician

    The laboratory of Professor Harris Wang in the Department of Systems Biology is seeking a research Technician B. The work in the Wang laboratory is focused on diverse questions in systems and synthetic biology including mammalian microbiome function, host-microbiome interactions in health and disease, microbial horizontal gene flow, and foundational technology development. The candidate for this position will carry out routine molecular biology and microbiology experiments, microbiome studies in vitro and in animal models, library preparations for next-generation sequencing, and microbial cultivation studies to serve ongoing projects.

  • Goverment Project Administrator

    Company Overview:

    Mission-driven LanzaTech is a revolutionary solution to climate change, capturing pollution to clean our skies and oceans and create new high value products for a sustainable future. LanzaTech captures pollution to make fuels and chemicals, including sustainable jet fuel and products you use every day. The technology is like retrofitting a brewery onto an emission source like a steel mill or a landfill site, but instead of using sugars and yeast to make beer, pollution is converted by biology to fuels and chemicals! Imagine a day when your plane is powered by recycled emissions, when your yoga pants started life as pollution from a steel mill. This future is possible using LanzaTech technology.

    • 2021 Biofuels Digest #1 Hottest Company in Renewable Fuels, Chemicals & Biomaterials
    • 2020 Biofuels Digest #3 Best Company to work for in the Advanced Bioeconomy
    • 2020 Fast Company World Changing Company
    • 2020 CNBC #43 on Top 50 Disrupter Companies list
    • 2019 Chicago Innovation Awards Winner
    • 2019 Fortune Magazine – Change the World – Companies to watch
    • 2019 Kirkpatrick Chemical Engineering Achievement Award

    LanzaTech is committed to Diversity, Equity & Inclusion as part of our mission, culture & core valuesThis position is open to candidates authorized to work in the United States on a full-time basis for any employer. LanzaTech is an Equal Employment Opportunity employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, gender, sexual orientation, gender identity or expression, national origin, age, genetic information, disability, or veteran status.

    Position Summary:

    Project monitoring and management support for LanzaTech’s portfolio of pioneering, technologically complex, multi-year projects that receive funding from government and other partners
    Support Government team leadership in ensuring successful project execution and reporting
    Directly interface with major stakeholders including internal technical team and project leads, government funding project monitors, as well as counterparts at sub-contractor and partner organizations

    Specific Roles:

    Project monitoring and management of government funded projects, including:

    Support project teams during project initiation and implementation
    Coordinate and implement workflows to facilitate project technical and financial objectives
    Monitor project performance against awarded cost, schedule, and milestones
    Coordinate and prepare written reports on project status including scheduling and tracking of progress and deliverables
    Design and prepare status summaries for Government team leadership

    Qualifications:

    BA or BS Degree required
    3+ years of experience monitoring and management of scientific research and/or engineering projects required
    Experience executing and/or managing government funded project is preferred.
    High proficiency with Microsoft Office required; experience with SharePoint preferred
    Demonstrated ability to work in a team environment
    Excellent data gathering and organization skills
    Excellent verbal and written communication skills

    Work Conditions:

    Able to work in a general office and desk environment.
    Sitting and working at a desk for long durations.
    Working on a computer for long durations.

  • Lead Scientist, Cell-Free

    Company Overview

    Mission-driven LanzaTech is a revolutionary solution to climate change, capturing pollution to clean our skies and oceans and create new high value products for a sustainable future. LanzaTech captures pollution to make fuels and chemicals, including sustainable jet fuel and products you use every day. The technology is like retrofitting a brewery onto an emission source like a steel mill or a landfill site, but instead of using sugars and yeast to make beer, pollution is converted by biology to fuels and chemicals! Imagine a day when your plane is powered by recycled emissions, when your yoga pants started life as pollution from a steel mill. This future is possible using LanzaTech technology.

    • 2021 Biofuels Digest #1 Hottest Company in Renewable Fuels, Chemicals & Biomaterials
    • 2020 Biofuels Digest #3 Best Company to work for in the Advanced Bioeconomy
    • 2020 Fast Company World Changing Company
    • 2020 CNBC #43 on Top 50 Disrupter Companies list
    • 2019 Chicago Innovation Awards Winner
    • 2019 Fortune Magazine – Change the World – Companies to watch
    • 2019 Kirkpatrick Chemical Engineering Achievement Award

    LanzaTech is committed to Diversity, Equity & Inclusion as part of our mission, culture & core values
    This position is open to candidates authorized to work in the United States on a full-time basis for any employer. LanzaTech is an Equal Employment Opportunity employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, gender, sexual orientation, gender identity or expression, national origin, age, genetic information, disability, or veteran status.

    About the Role

    LanzaTech is looking for a motivated, high energy, well-organized, collaborative Scientist to lead research and development of cell-free technologies at LanzaTech. The role will include:

    Work on a cross-functional team to support projects that require and/or would benefit from cell-free applications and experiments
    Leading the development, optimization, and automation of cell-free protein synthesis workflows both in model systems and gas-fermenting organisms
    Evaluating and leading testing of additional cell-free applications such as biosensors and manufacturing
    Conducting work collaboratively across multiple teams at LanzaTech including Automation, Fermentation, Analytics, and Engineering

    Responsibilities

    Follow all safety requirements for working in the offices and laboratories, including completing any required trainings
    Maintain a clean and functional laboratory space
    Assist in upkeep of laboratory reagents and stock supplies to run experiments
    Maintain an up-to-date laboratory notebook tracking experiments, data, and interpretation of results
    Perform cell-free experiments and workflows in support of externally funded projects
    Lead the development of new cell-free workflows and capabilities at LanzaTech
    Establish and write standard operating procedures (SOPs) for laboratory workflows
    Stay up-to-date with advancements in cell-free scientific field
    Attend and participate in Enzymology and Synthetic Biology group meetings as well as relevant project updates with partners
    Present findings and developments both internally to LanzaTech teams and externally to partners
    Instruct and advise LanzaTech colleagues on established workflows
    Guide and train junior scientists such as research associates, technicians, and interns
    Develop research plans and preliminary data in support of grant proposals
    Use of laboratory management systems, in-house experimental design tools, and computational tools to improve efficiency in design, execution, and interpretation of experiments

    Requirements

    Minimum

    Ph.D. in Biochemistry, Synthetic Biology, Bioengineering, Molecular Biology, Chemical Engineering, or a related field OR M.Sc. in related field with 2+ years relevant laboratory experience with cell-free applications post-graduation
    Demonstrated experience with designing, executing, and reporting cell-free experiments
    Knowledgeable with the current cell-free protein synthesis/cell-free applications field
    Strong organizational, time management, and interpersonal skills
    Experience writing reports and/or manuscripts centered on cell-free applications (e.g., transcription, translation, sensing and screening)
    Experience giving group presentations
    High attention to detail and careful record keeping
    Independent and highly self-motivated
    Excellent communication skills and a desire to work in a team
    Ability to conduct research independently and manage multiple tasks in parallel
    Awareness of safety issues in the work environment
    Strong computer literacy including Microsoft Office, SharePoint or equivalent applications

    Highly Preferred

    Experience and/or working knowledge of anaerobic microbes
    Experience with multiple cell-free protein synthesis systems (e.g., E. coli and Wheat Germ)
    Experience with multiple protein reporter, detection, and/or quantification approaches (e.g., luciferase, radiolabeling, and blotting)
    Experience with multiple DNA cloning methods (e.g., Gibson and Golden Gate assemblies)

    Location

    LanzaTech Headquarters
    Skokie, IL USA

    Apply HERE

  • Scientist, Automation Scientist

    Company Overview

    Mission-driven LanzaTech is a revolutionary solution to climate change, capturing pollution to clean our skies and oceans and create new high value products for a sustainable future. LanzaTech captures pollution to make fuels and chemicals, including sustainable jet fuel and products you use every day. The technology is like retrofitting a brewery onto an emission source like a steel mill or a landfill site, but instead of using sugars and yeast to make beer, pollution is converted by biology to fuels and chemicals! Imagine a day when your plane is powered by recycled emissions, when your yoga pants started life as pollution from a steel mill. This future is possible using LanzaTech technology.

    • 2021 Biofuels Digest #1 Hottest Company in Renewable Fuels, Chemicals & Biomaterials
    • 2020 Biofuels Digest #3 Best Company to work for in the Advanced Bioeconomy
    • 2020 Fast Company World Changing Company
    • 2020 CNBC #43 on Top 50 Disrupter Companies list
    • 2019 Chicago Innovation Awards Winner
    • 2019 Fortune Magazine – Change the World – Companies to watch
    • 2019 Kirkpatrick Chemical Engineering Achievement Award

    LanzaTech is committed to Diversity, Equity & Inclusion as part of our mission, culture & core values
    This position is open to candidates authorized to work in the United States on a full-time basis for any employer. LanzaTech is an Equal Employment Opportunity employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, gender, sexual orientation, gender identity or expression, national origin, age, genetic information, disability, or veteran status.

    About the Role

    We are seeking an Automation Scientist to, develop automated and high throughput method for a number of tasks upstream and downstream of LanzaTech BioFoundry LanzaTech has designed, built and operates the world-first anaerobic biofoundry, a fully integrated platform of several automated modules with the capability of growing and manipulating thousands of anaerobic strains on gaseous feedstocks. A successful candidate will join LanzaTech’s Automation team and be a part of an effort pushing the boundaries of automation in context of anaerobic conditions and non-model organisms. The Automation team is a cross-functional team within LanzaTech’s Synthetic Biology group who support a variety of projects both within the group and across the company.

    Activities include Will primarily involve assisting not only the automation team in developing new workflows but also other team within the company that has automation amenable workflows. A successful candidate will also be expected to participate in data capture through both automated and semi-automated data management systems and the daily execution of high-throughput experiments and method development and optimization as well as coordination with various project teams.

    Duties & Responsibilities:

    Developing automated workflows for a number of teams within lanzatech
    Daily operations of developed workflows and general automation team work
    Definition, development and optimization of high-throughput workflows including integration of new instruments, emerging technologies and information systems;
    Use of laboratory information management systems (LIMS) and bioinformatics software tools and databases including data capture from high-throughput experiments and analysis of statistics and results against model predictions;
    Work in cross-functional setting including coordination with project team leaders;
    Attend seminars and participate in group and project meetings or lab activities as required.

    Requirements:

    M.Sc. or B.Sc. (or equivalent) in Synthetic Biology, Bioengineering, Biochemistry, Molecular Biology, Chemical Engineering or a related field.
    Minimum of 2 years’ experience in biotechnology industry, a biofoundry or a high-throughput environment with hand-on experience in high-throughput workflow development and/or execution, preferentially with high throughput microbial culture screening.
    Proficient in working with laboratory automation software and/or programming as well as statistics. Programming Hamilton liquid handing systems (Venus programming) and Thermo scheduling software (Momentum™) is highly preferred.
    Strong organizational, time management, and interpersonal skills. Ability to multi-task and keep track of multiple tasks and projects at the same time. High attention to detail and careful record keeping.
    Independent and highly self-motivated. Excellent communication skills and team-work oriented.
    Awareness of safety issues in the work environment.

    Desirable Skills:

    Proficiency in programming (e.g. Python)
    Experience with SQL databases and LIMS systems
    Experience with cell sorting
    Experience with microfluidics.
    Experience working with anaerobic microbes.

    Location

    LanzaTech Headquarters
    Skokie, IL USA

    Apply HERE

  • Senior Research Associate, CRISPR

    Company Overview

    Mission-driven LanzaTech is a revolutionary solution to climate change, capturing pollution to clean our skies and oceans and create new high value products for a sustainable future. LanzaTech captures pollution to make fuels and chemicals, including sustainable jet fuel and products you use every day. The technology is like retrofitting a brewery onto an emission source like a steel mill or a landfill site, but instead of using sugars and yeast to make beer, pollution is converted by biology to fuels and chemicals! Imagine a day when your plane is powered by recycled emissions, when your yoga pants started life as pollution from a steel mill. This future is possible using LanzaTech technology.

    • 2021 Biofuels Digest #1 Hottest Company in Renewable Fuels, Chemicals & Biomaterials
    • 2020 Biofuels Digest #3 Best Company to work for in the Advanced Bioeconomy
    • 2020 Fast Company World Changing Company
    • 2020 CNBC #43 on Top 50 Disrupter Companies list
    • 2019 Chicago Innovation Awards Winner
    • 2019 Fortune Magazine – Change the World – Companies to watch
    • 2019 Kirkpatrick Chemical Engineering Achievement Award

    LanzaTech is committed to Diversity, Equity & Inclusion as part of our mission, culture & core values
    This position is open to candidates authorized to work in the United States on a full-time basis for any employer. LanzaTech is an Equal Employment Opportunity employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, gender, sexual orientation, gender identity or expression, national origin, age, genetic information, disability, or veteran status.

    About the Role

    We are seeking a Research Associate to develop and execute experiments leveraging CRISPR-based synthetic biology techniques towards engineering and characterization of LanzaTech’s proprietary gas fermenting microbes. The Research Associate will be joining LanzaTech’s Synthetic Biology team, working in the lab and interacting with other teams across the company. This role will support Senior Scientists on project-based work as well as a variety of lab management tasks. The Research Associate will work towards both specific goals and towards improving workflows to benefit all Synthetic Biology team members. Types of activities include plasmid construction, bacterial transformation and culturing, DNA QC, product screening, genetic parts characterization, curating plasmid repositories, preparing buffer and media, stocking consumables, authoring training and protocol documents, data analysis, ect. Overly qualified applications may be considered at

    Duties & Responsibilities:

    Design, assembly, and transformation of DNA constructs
    Genetic modification and selection of LanzaTech proprietary microbes
    High-throughput cultivation and screening of LanzaTech proprietary microbes
    Analysis of data and interpretation of results against model predictions
    Use of computational tools and databases
    Execute established workflows and implement improvements
    Support organization of training, protocol, and other document development
    Maintain a laboratory notebook, track and QC data in LIMS system as required
    Attend seminars and participate in group and project meetings and lab activities

    Requirements:

    M.Sc. or B.Sc. (or equivalent) in Synthetic Biology, Bioengineering, Molecular Biology, Chemical Engineering, Computational Biology, or a related field with preferable 1-2 years of relevant experience (RA) or 3-5 years (Senior RA) in a laboratory setting
    Experience in cloning and assembly of DNA and growth of microbes or experience with NGS statistical analysis and an interest in performing wet-lab biology
    Knowledge of CRISPR-Cas systems
    Use of word processing, data collaboration tools, presentation and spreadsheet applications, and familiarity with concepts in statistics and tools to analyze data
    Strong organizational, time management, record keeping, self and prioritization skills
    Independent, hard-working, forward thinking, and highly self-motivated
    Excellent communication and interpersonal relationship skills
    Desire to work in a team and assist other team members
    Awareness of safety issues in the work environment

    Highly preferred:

    Experience different cloning methods such as Gibson or Golden Gate assembly and genetic tools such as CRISPR and homologous recombination
    Experience working with DNA design software and analysis of NGS data
    Strong computer literacy, including Microsoft Excel, PowerPoint, and Outlook
    Experience with at least one programming language, such as but not limited to Python, Java, R, or other statistical analysis pipelines
    Ability to conduct research independently and manage multiple tasks in parallel
    Experience with gas fermentation or working with anaerobic systems
    Experience conducting, reporting, and presenting experiments

    Location

    LanzaTech Headquarters
    Skokie, IL USA

    Apply HERE

  • Research Associate, DNA Assembly

    Company Overview

    Mission-driven LanzaTech is a revolutionary solution to climate change, capturing pollution to clean our skies and oceans and create new high value products for a sustainable future. LanzaTech captures pollution to make fuels and chemicals, including sustainable jet fuel and products you use every day. The technology is like retrofitting a brewery onto an emission source like a steel mill or a landfill site, but instead of using sugars and yeast to make beer, pollution is converted by biology to fuels and chemicals! Imagine a day when your plane is powered by recycled emissions, when your yoga pants started life as pollution from a steel mill. This future is possible using LanzaTech technology.

    • 2021 Biofuels Digest #1 Hottest Company in Renewable Fuels, Chemicals & Biomaterials
    • 2020 Biofuels Digest #3 Best Company to work for in the Advanced Bioeconomy
    • 2020 Fast Company World Changing Company
    • 2020 CNBC #43 on Top 50 Disrupter Companies list
    • 2019 Chicago Innovation Awards Winner
    • 2019 Fortune Magazine – Change the World – Companies to watch
    • 2019 Kirkpatrick Chemical Engineering Achievement Award

    LanzaTech is committed to Diversity, Equity & Inclusion as part of our mission, culture & core values
    This position is open to candidates authorized to work in the United States on a full-time basis for any employer. LanzaTech is an Equal Employment Opportunity employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, gender, sexual orientation, gender identity or expression, national origin, age, genetic information, disability, or veteran status.

    About the Role

    LanzaTech is looking for a motivated, high energy, well-organized, collaborative Research Associate to support its high throughput DNA assembly pipeline.

    This person will work on a cross-functional team to support projects with their DNA assembly needs
    The Research Associate will work with the Automation team to develop, execute and optimize DNA assembly methods
    They will conduct their work collaboratively across multiple projects and functional teams

    Responsibilities

    Follow all safety requirements for working in the offices and laboratories, including completing any required training
    Maintain a clean and functional laboratory space
    Assist in the upkeep of laboratory reagents and stock supplies to run experiments
    Enter and update data in LIMS systems
    Daily running and maintenance of LanzaTech’s DNA assembly automated platform
    Attend and participate in Automation and Synthetic Biology group meetings as well as relevant project updates with partners
    Present findings and developments both internally to LanzaTech teams and externally to partners
    Use of laboratory management systems, in-house experimental design tools, and computational tools to improve efficiency in design, execution, and interpretation of experiments
    Assist in both training and development support of DNA assembly-related software tools

    Requirements

    Minimum

    B.Sc. or M.Sc. in Biochemistry, Synthetic Biology, Bioengineering, Molecular Biology, Chemical Engineering, or a related field
    Knowledgeable with cutting edge DNA assembly methods
    Experience using automated DNA assembly methods and equipment
    Strong organizational, time management, and interpersonal skills
    Experience writing reports and manuscripts
    Experience giving oral presentations
    High attention to detail and careful record-keeping
    Independent and highly self-motivated
    Excellent communication skills and a desire to work collaboratively in a team
    Awareness of safety issues in the work environment
    Strong computer literacy with Microsoft Office, SharePoint, or equivalent applications

    Preferred

    User level experience with Hamilton Venus
    Experience with DNA CAD and LIMS systems
    Ability to conduct research independently and manage multiple tasks in parallel

    Location

    LanzaTech Headquarters
    Skokie, IL USA

    Apply HERE

  • Research Associate, Cell-Free

    Company Overview

    Mission-driven LanzaTech is a revolutionary solution to climate change, capturing pollution to clean our skies and oceans and create new high value products for a sustainable future. LanzaTech captures pollution to make fuels and chemicals, including sustainable jet fuel and products you use every day. The technology is like retrofitting a brewery onto an emission source like a steel mill or a landfill site, but instead of using sugars and yeast to make beer, pollution is converted by biology to fuels and chemicals! Imagine a day when your plane is powered by recycled emissions, when your yoga pants started life as pollution from a steel mill. This future is possible using LanzaTech technology.

    • 2021 Biofuels Digest #1 Hottest Company in Renewable Fuels, Chemicals & Biomaterials
    • 2020 Biofuels Digest #3 Best Company to work for in the Advanced Bioeconomy
    • 2020 Fast Company World Changing Company
    • 2020 CNBC #43 on Top 50 Disrupter Companies list
    • 2019 Chicago Innovation Awards Winner
    • 2019 Fortune Magazine – Change the World – Companies to watch
    • 2019 Kirkpatrick Chemical Engineering Achievement Award

    LanzaTech is committed to Diversity, Equity & Inclusion as part of our mission, culture & core values
    This position is open to candidates authorized to work in the United States on a full-time basis for any employer. LanzaTech is an Equal Employment Opportunity employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, gender, sexual orientation, gender identity or expression, national origin, age, genetic information, disability, or veteran status.

    About the Role

    LanzaTech is looking for a motivated, high energy, well-organized, collaborative Research Associate to support research and development of cell-free technologies within the context of industrial gas-fermenting bacteria.

    This person will work on a cross-functional team to support projects that require and/or would benefit from cell-free applications and experiments
    The Research Associate will work with the Enzymology team to develop and execute various cell-free protein synthesis workflows both in model systems and gas-fermenting organisms
    They will also participate in evaluating and testing additional cell-free applications such as biosensors and manufacturing
    They will conduct their work collaboratively across multiple teams at LanzaTech including Synthetic Biology, Fermentation, and Analytics

    Responsibilities

    Follow all safety requirements for working in the offices and laboratories, including completing any required trainings
    Maintain a clean and functional laboratory space
    Assist in upkeep of laboratory reagents and stock supplies in order to run experiments
    Maintain an up-to-date laboratory notebook tracking experiments, data, and interpretation of results
    Perform cell-free experiments and workflows in support of externally funded projects
    Establish and write standard operating procedures (SOPs) for laboratory workflows
    Attend and participate in Enzymology and Synthetic Biology group meetings as well as relevant project updates with partners
    Present findings and developments both internally to LanzaTech teams and externally to partners
    Use of laboratory management systems, in-house experimental design tools, and computational tools to improve efficiency in design, execution, and interpretation of experiments

    Requirements

    Minimum

    B.Sc. or M.Sc. in Biochemistry, Synthetic Biology, Bioengineering, Molecular Biology, Chemical Engineering, or a related field
    Knowledgeable with a current cell-free protein synthesis/expression or other cell-free application
    Strong organizational, time management, and interpersonal skills
    Experience writing reports and/or manuscripts
    Experience giving oral presentations
    High attention to detail and careful record keeping
    Independent and highly self-motivated
    Excellent communication skills and a desire to work in a team
    Awareness of safety issues in the work environment
    Strong computer literacy with Microsoft Office, SharePoint, or equivalent applications

    Highly Preferred

    Direct experience with multiple cell-free protein synthesis applications
    Experience and/or working knowledge of anaerobic microbes
    Experience with protein reporter, detection, and/or quantification approaches (e.g., luciferase, radiolabeling, and blotting)
    Experience with DNA cloning methods (e.g., Gibson and Golden Gate assemblies)
    Ability to conduct research independently and manage multiple tasks in parallel

    Location

    LanzaTech Headquarters
    Skokie, IL USA

    Apply HERE

  • Research Associate, Metabolic Engineering

    Company Overview

    Mission-driven LanzaTech is a revolutionary solution to climate change, capturing pollution to clean our skies and oceans and create new high value products for a sustainable future. LanzaTech captures pollution to make fuels and chemicals, including sustainable jet fuel and products you use every day. The technology is like retrofitting a brewery onto an emission source like a steel mill or a landfill site, but instead of using sugars and yeast to make beer, pollution is converted by biology to fuels and chemicals! Imagine a day when your plane is powered by recycled emissions, when your yoga pants started life as pollution from a steel mill. This future is possible using LanzaTech technology.

    • 2021 Biofuels Digest #1 Hottest Company in Renewable Fuels, Chemicals & Biomaterials
    • 2020 Biofuels Digest #3 Best Company to work for in the Advanced Bioeconomy
    • 2020 Fast Company World Changing Company
    • 2020 CNBC #43 on Top 50 Disrupter Companies list
    • 2019 Chicago Innovation Awards Winner
    • 2019 Fortune Magazine – Change the World – Companies to watch
    • 2019 Kirkpatrick Chemical Engineering Achievement Award

    LanzaTech is committed to Diversity, Equity & Inclusion as part of our mission, culture & core values
    This position is open to candidates authorized to work in the United States on a full-time basis for any employer. LanzaTech is an Equal Employment Opportunity employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, gender, sexual orientation, gender identity or expression, national origin, age, genetic information, disability, or veteran status.

    About the Role

    We are seeking a Research Associate to improve laboratory processes and support metabolic engineering and characterization of LanzaTech’s proprietary gas fermenting microbes. The Research Associate will be joining LanzaTech’s Synthetic Biology team, working in the lab and interacting with other teams across the company. This role will support Senior Scientists on project-based work as well as a variety of lab management tasks. The Research Associate will work towards both specific goals and towards improving workflows to benefit all Synthetic Biology team members. Types of activities include plasmid construction, bacterial transformation and culturing, confirmation of clones, product screening, genetic parts characterization, curating strain and plasmid repositories, preparing buffer and media, stocking consumables, authoring training and protocol documents, etc.

    Duties & Responsibilities:

    Design, cloning and assembly of multi-fragment DNA constructs for heterologous pathway expression
    Genetic modification and selection of LanzaTech proprietary microbes
    High-throughput cultivation and screening of LanzaTech proprietary microbes
    Analysis of data and interpretation of results against model predictions
    Use of computational tools and databases
    Learn established workflows and implement improvements
    Support organization of training, protocol, and other document development
    Assist in general lab chores such as solution prep, cleaning, organization, etc.
    Maintain a laboratory notebook, track and QC data in LIMS system as required
    Attend seminars and participate in group and project meetings and lab activities

    Requirements:

    M.Sc. or B.Sc. (or equivalent) in Synthetic Biology, Bioengineering, Biochemistry, Molecular Biology, Chemical Engineering or a related field with preferable 1-2 years of relevant experience in a laboratory setting
    Hands-on experience in cloning and assembly of DNA and growth of microbes
    Use of DNA design software, word processing, data collaboration tools, presentation and spreadsheet applications, and familiarity with concepts in statistics and tools to analyze data
    Strong organizational, time management, record keeping, and prioritization skills
    Independent, hard-working, and highly self-motivated
    Excellent communication and interpersonal relationship skills
    Ability to maintain a positive attitude when faced with challenges
    Desire to work in a team and assist other team members
    Awareness of safety issues in the work environment

    Highly preferred:

    Experience with gas fermentation
    Experience in biotech industry
    Experience with metabolic engineering
    Experience different cloning methods such as Gibson or Golden Gate assembly and genetic tools such as CRISPR and homologous recombination
    Experience working with genetic and metabolic pathway databases and DNA design software
    Experience working with anaerobic microbes
    Experience working with automated liquid handler
    Strong computer literacy, including Office, SharePoint; Experience in scripting and working with large datasets is preferred
    Ability to conduct research independently and manage multiple tasks in parallel

    Location

    LanzaTech Headquarters
    Skokie, IL USA

     

    Apply HERE

  • Research Associate, Synthetic Biology

    About LanzaTech

    Mission-driven LanzaTech is a revolutionary solution to climate change, capturing pollution to clean our skies and oceans and create new high value products for a sustainable future. LanzaTech captures pollution to make fuels and chemicals, including sustainable jet fuel and products you use every day. The technology is like retrofitting a brewery onto an emission source like a steel mill or a landfill site, but instead of using sugars and yeast to make beer, pollution is converted by biology to fuels and chemicals! Imagine a day when your plane is powered by recycled emissions, when your yoga pants started life as pollution from a steel mill. This future is possible using LanzaTech technology.

    • 2020 Biofuels Digest #3 Best Company to work for in the Advanced Bioeconomy
    • 2019 Chicago Innovation Awards Winner
    • 2019 CNBC #15 on Top 50 Disrupter Companies
    • 2019 Fortune Magazine – Change the World – Companies to watch
    • 2019 Kirkpatrick Chemical Engineering Achievement Award

    LanzaTech is committed to Diversity, Equity & Inclusion as part of our mission, culture & core values
    This position is open to candidates authorized to work in the United States on a full-time basis for any employer. LanzaTech is an Equal Employment Opportunity employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, gender, sexual orientation, gender identity or expression, national origin, age, genetic information, disability, or veteran status.

    About the role

    We are seeking a Research Associate to improve laboratory processes and support metabolic engineering and characterization of LanzaTech’s proprietary gas fermenting microbes. The Research Associate will be joining LanzaTech’s Synthetic Biology team, working in the lab and interacting with other teams across the company. This role will support Senior Scientists on project-based work as well as a variety of lab management tasks. The Research Associate will work towards both specific goals and towards improving workflows to benefit all Synthetic Biology team members. Types of activities include plasmid construction, bacterial transformation and culturing, confirmation of clones, product screening, genetic parts characterization, curating strain and plasmid repositories, preparing buffer and media, stocking consumables, authoring training and protocol documents, etc.

    Key duties

    Design, cloning and assembly of multi-fragment DNA constructs for heterologous pathway expression
    Genetic modification and selection of LanzaTech proprietary microbes
    High-throughput cultivation and screening of LanzaTech proprietary microbes
    Analysis of data and interpretation of results against model predictions
    Use of computational tools and databases
    Learn established workflows and implement improvements
    Support organization of training, protocol, and other document development
    Assist in general lab chores such as solution prep, cleaning, organization, etc.
    Maintain a laboratory notebook, track and QC data in LIMS system as required
    Attend seminars and participate in group and project meetings and lab activities

    Required Qualifications

    M.Sc. or B.Sc. (or equivalent) in Synthetic Biology, Bioengineering, Biochemistry, Molecular Biology, Chemical Engineering or a related field with preferable 1-2 years of relevant experience in a laboratory setting
    Hands-on experience in cloning and assembly of DNA and growth of microbes
    Use of DNA design software, word processing, data collaboration tools, presentation and spreadsheet applications, and familiarity with concepts in statistics and tools to analyze data
    Strong organizational, time management, record keeping, and prioritization skills
    Independent, hard-working, and highly self-motivated
    Excellent communication and interpersonal relationship skills
    Ability to maintain a positive attitude when faced with challenges
    Desire to work in a team and assist other team members
    Awareness of safety issues in the work environment

    Preferred/Valued

    Experience with gas fermentation
    Experience in biotech industry
    Experience with metabolic engineering
    Experience different cloning methods such as Gibson or Golden Gate assembly and genetic tools such as CRISPR and homologous recombination
    Experience working with genetic and metabolic pathway databases and DNA design software
    Experience working with anaerobic microbes
    Strong computer literacy, including Office, SharePoint; Experience in scripting and working with large datasets is preferred
    Ability to conduct research independently and manage multiple tasks in parallel

    Physical Requirements

    Prolonged periods of sitting at a desk and working on a computer
    Prolonged periods of standing in the lab

    Work Environment

    HQ in Skokie, IL

     

    Apply HERE

  • ORISE fellow (Bachelor’s or Master’s level) – Biomanufacturing

    The Department of Defense (DoD) is offering a post-graduate internship at the U.S. Army Combat Capabilities Development Command – Chemical Biological Center (DEVCOM-CBC) within The Research and Technology (R&T) Directorate.

    As an ORISE participant, you will join a community of scientists and researchers in an effort to support The Research and Technology (R&T) Directorate within CCDC Chemical Biological Center, with a mission to provide integrated science and technology solutions to identify and mitigate novel and emerging chemical and biological threats.

    Why should I apply?
    Under the guidance of a mentor, you will gain hands-on experience to complement your education and support your academic and professional goals. During your appointment, you will participate in the configuration and operation of DEVCOM-CBC’s Biomanufacturing process development pilot plant. You will also have an opportunity to gain experience in fermentation, downstream processing, and biochemical analysis of the products of organisms modified using the techniques of synthetic biology at varying stages of purification and manufacture.

    Along the way, you will collaborate with team personnel to design and implement biological and chemical engineering strategies for production of critical chemicals and precursors, gaining exposure to production techniques including but not limited to medium- and large-scale fermentation, centrifugation, tangential-flow filtration, chromatography, distillation, and/or extraction. Under the mentorship of DEVCOM-CBC senior scientists, you will learn analytical techniques which will include HPLC, LC-MS, and GC-MS.

    In addition, you will learn and engage in activities which include but are not limited to:

    Technoeconomic analyses
    Process safety analysis
    Risk assessment
    Hazard mitigation in large-scale process development

    Where will I be located?
    Aberdeen Proving Ground, Maryland

    What is the anticipated start date?
    The DEVCOM-CBC is ready to make appointments immediately. Exact start dates will be determined at the time of selection and in coordination with the selected candidate. Applications are reviewed on an ongoing basis and internships will be filled as qualified candidates are identified.

    Appointment Length
    This appointment is a twelve month research appointment, with the possibility to be renewed for additional research periods. Appointments may be extended depending on funding availability, project assignment, program rules, and availability of the participant.

    What are the benefits?
    You will receive a stipend to be determined by DEVCOM-CBC. Stipends are typically based on a participant’s academic standing, discipline, experience, and research facility location. Other benefits may include the following:

    Health Insurance Supplement. Participants are eligible to purchase health insurance through ORISE.
    Relocation Allowance
    Training and Travel Allowance
    Nature of Appointment

    You will not enter into an employee/employer relationship with ORISE, ORAU, DoD, or any other office or agency. Instead, you will be affiliated with ORISE for the administration of the appointment through the ORISE appointment letter and Terms of Appointment.

    About DEVCOM-CBC
    U.S. Army Combat Capabilities Development Command Chemical Biological Center (DEVCOM-CBC) conducts applied research and development for the detection and identification of chemical, biological, and explosive materials to provide next-generation detection capabilities to the Warfighter. The Research and Technology (R&T) Directorate operates within CCDC Chemical Biological Center, with a mission to provide integrated science and technology solutions to identify and mitigate novel and emerging chemical and biological threats. The R&T Directorate specializes in the research and development of innovative technological solutions to solve chemical and biological defense threats to our nation—both abroad and in the homeland.

    Beginning in 2021, DEVCOM-CBC’s Biotechnology Branch begins a 2-year modernization and expansion effort of its 25,000 square-foot biomanufacturing research and development laboratory. Currently, the facility houses its bioproduction operations, featuring fermentation vessels up to 1000 liters capacity and downstream processing capability for bacterial and phage-based products. In the coming years, the facility will expand its capabilities to include downstream processing of critical specialty chemicals, precursor molecules, advanced bio-inspired polymer materials, and other military-relevant biologically derived products. At the completion of the modernization effort, the Biotechnology branch will serve the DoD as a pilot-scale biomanufacturing research and process development facility.

  • NRC Research Associate (postdoc or senior associate)

    We are seeking a candidate to work within the Chemical and Biological Center’s 20,000 square foot pilot-scale fermentation facility. DOD is realizing a surge in programs that are metabolically engineering yeast and bacteria to produce chemicals with unique properties. These are being developed into materials to support a wide variety of projects. Each requires scale up to 1500 liters, downstream processing, and characterization at labs located across the Edgewood campus. The successful candidate will interact with a multi-disciplinary team of material scientists, chemists, and biologists. The endeavour has regular interaction with academia and industry as part of a manufacturing consortium that spans the continetal United States. Good communication and problem solving skills are needed. Specific training will be provided with an opportunity for growth and international travel. Please contact for questions and background.

    POCs for questions about this opportunity are
    Peter Emanuel ([email protected])
    Henry Gibbons ([email protected])

  • NRC postdoc – Biomanufacturing

    Biomanufacturing is increasingly being viewed as an important tool to provide alternative and flexible domestic manufacturing capabilities for an agile supply chain. These technologies promise to boost the economy and secure domestic supply of important products, such as medicines or fuels. Traditionally, the vast majority of biomanufacturing efforts use cells in bioreactors to simultaneously grow and produce target products from cheap feedstocks. Cell-free systems are an emerging alternative in which cells are grown first and their expression and metabolic machinery harvested, followed by manufacturing of products using the extracted machinery. This approach has several advantages to cell-based manufacturing, including reduced sensitivity to products that inhibit growth, ability to produce products that are larger than the size of a cell, and rapid design and testing cycles that circumvent cloning. We are seeking NRC candidates that can support our efforts in cell-free biomanufacturing. Qualified candidates will have experience in cell-free systems, biomanufacturing, metabolic engineering, fermentation scale-up, microbiology, or synthetic biology; ideal candidates will have experience in both cell-free systems and biomanufacturing. Candidates will need to be flexible and willing to adapt to multiple roles within a large and evolving program.

    This project is a collaboration between U.S. Army and Northwestern University and offers opportunities for exchange among DOD, academic, and industry partners.

    Any questions can be directed to myself and the primary POC, Matt Lux ([email protected])

  • Lead Scientist, HTP Strain Screening

    Company Overview

    Mission-driven LanzaTech is a revolutionary solution to climate change, capturing pollution to clean our skies and oceans and create new high value products for a sustainable future. LanzaTech captures pollution to make fuels and chemicals, including sustainable jet fuel and products you use every day. The technology is like retrofitting a brewery onto an emission source like a steel mill or a landfill site, but instead of using sugars and yeast to make beer, pollution is converted by biology to fuels and chemicals! Imagine a day when your plane is powered by recycled emissions, when your yoga pants started life as pollution from a steel mill. This future is possible using LanzaTech technology.

    • 2021 Biofuels Digest #1 Hottest Company in Renewable Fuels, Chemicals & Biomaterials
    • 2020 Biofuels Digest #3 Best Company to work for in the Advanced Bioeconomy
    • 2020 Fast Company World Changing Company
    • 2020 CNBC #43 on Top 50 Disrupter Companies list
    • 2019 Chicago Innovation Awards Winner
    • 2019 Fortune Magazine – Change the World – Companies to watch
    • 2019 Kirkpatrick Chemical Engineering Achievement Award

    LanzaTech is committed to Diversity, Equity & Inclusion as part of our mission, culture & core values
    This position is open to candidates authorized to work in the United States on a full-time basis for any employer. LanzaTech is an Equal Employment Opportunity employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, gender, sexual orientation, gender identity or expression, national origin, age, genetic information, disability, or veteran status.

    About the Role

    We are seeking an Automation Scientist to oversee LanzaTech’s biofoundry and high-throughput strain development pipeline, supporting the development of proprietary gas fermenting microbes for production of new molecules from waste gases. LanzaTech has designed, built and operates the world-first anaerobic biofoundry, a fully integrated platform of several automated modules with the capability of growing and manipulating thousands of anaerobic strains on gaseous feedstocks. A successful candidate will join LanzaTech’s Automation team and be a part of an effort pushing the boundaries of automation in context of anaerobic conditions and non-model organisms. The Automation team is a cross-functional team within LanzaTech’s Synthetic Biology group who support a variety of projects both within the group and across the company.

    Activities include automated, high-throughput bacterial transformation and culturing, strain quality control, and product screening as well as integration of new devices and emerging technologies. A successful candidate will also be expected to participate in data capture through both automated and semi-automated data management systems and the daily execution of high-throughput experiments and method development and optimization as well as coordination with various project teams.

    Duties & Responsibilities:

    Oversight and day-to-day operation of LanzaTech’s biofoundry and other automation systems including high-throughput culture, transformation, and screening of LanzaTech proprietary microbes;
    Definition, development and optimization of high-throughput workflows including integration of new instruments, emerging technologies and information systems;
    Aid in the further development of automated samples tracking and data capture by working the Computation Sciences and Computational Biology teams
    Use of laboratory information management systems (LIMS) and bioinformatics software tools and databases including data capture from high-throughput experiments and analysis of statistics and results against model predictions;
    Work in cross-functional setting including coordination with project team leaders;
    Attend seminars and participate in group and project meetings or lab activities as required.

    Requirements:

    M.Sc. or B.Sc. (or equivalent) in Synthetic Biology, Bioengineering, Biochemistry, Molecular Biology, Chemical Engineering or a related field.
    Minimum of 2 years’ experience in biotechnology industry, a biofoundry or a high-throughput environment with hand-on experience in high-throughput workflow development and/or execution, preferentially with high throughput microbial culture screening.
    Proficient in working with laboratory automation software and/or programming as well as statistics. Programming Hamilton liquid handing systems (Venus programming) and Thermo scheduling software (Momentum™) is highly preferred.
    Strong organizational, time management, and interpersonal skills. Ability to multi-task and keep track of multiple tasks and projects at the same time. High attention to detail and careful record keeping.
    Independent and highly self-motivated. Excellent communication skills and team-work oriented.
    Awareness of safety issues in the work environment.

    Desirable Skills:

    Proficiency in programming (e.g. Python)
    Experience with cell sorting
    Experience with microfluidics.
    Experience working with anaerobic microbes.

    Apply HERE

  • Bioinformatics Scientist

    Zymergen is hiring a Bioinformatics Scientist for enzyme optimization in strain engineering programs, via iterative cycles of Design-Build-Test-Learn, each supported by software-aided design and analysis software. The Bioinformatics Scientist will focus on working with colleagues to develop strategies and data-driven approaches to sampling enzyme diversity from metagenomic sequences, as well as enzyme performance optimization via protein engineering. The Scientist will join a team of Bioinformatics and Data Scientists working on metabolic pathway and strain design, genetic construct design, phenotype and genome analysis. Our aim is to improve the performance of microbes via multiple, iterative, rounds of genome engineering. In addition, the Scientist will be part of a larger technical team to develop best practices in designing strain edits and computer-aided learning for strain performance improvement.

    Responsibilities

    Explore state-of-the-art machine learning approaches to structure & function prediction from protein sequences, using our in-house LIMS datasets of sequences paired with enzyme performance data.
    Develop enzyme sequence selection strategies to sample enzyme sequence diversity contained in our proprietary metagenomics libraries, with 250M+ metagenomic sequences
    Evaluate available literature for a variety of metabolic enzymes in order to suggest strategies for metagenomic enzyme selection
    Prepare and present organized work plans and work product to multiple levels of management and diverse audiences
    Collaborate with academic and industrial business partners as needed to evaluate new technologies and/or to pursue joint ventures

    Qualifications/Experience

    • Master’s (or Bachelor’s with 2+ years ML experience) in one of the following relevant disciplines: Computer Science, Bioinformatics, Computational Biology, Biochemistry, Cell Biology,
    • Metabolic Engineering
    • Strong Python coding experience, including object-oriented programming
    • Experience with biological sequence handling (DNA/RNA/protein)
    • Experience with Tensorflow, PyTorch or related ML frameworks
    • Experience with SQL DB access via Python
    • Strong desire to collaborate and work with teams
    • Strong interpersonal skills. As a team, we work from a base of trust and assumption of good will

    Preferred Qualifications

    • Ph.D. in a relevant discipline
    • Rosetta, PyMol or related protein structural analysis
    • Experience with protein engineering
    • Experience in a metabolic engineering lab or company
    • Experience with ‘omics analysis (proteomics, genomics, metabolomics, etc.)
    • Experience with evolutionary and co-evolutionary analysis of protein sequences.
    • Experience with deep neural networks for biological sequences (e.g. Transformers, LSTMs, CNNs)

    Additional Details
    You should be familiar with (at least through coursework) and ideally, have applied current approaches to protein sequence modeling and structure / function prediction. Examples of these include Transformers (e.g. ESM-1b or MSA Transformer), LSTMs (e.g. UniRep), generative adversarial networks (GANs), autoencoders, convolutional neural networks (CNNs), as well as other deep neural network (DNN) architectures.

    You should have some experience in machine learning (ML) frameworks, including (but not limited to) PyTorch, Keras, Tensorflow, scikit-learn, caret (in R language), etc.

    You will need sufficient Python software engineering experience, above the level of a typical bioinformatics scientist (i.e. at the level of a Software Engineer I-II). This candidate should have a good understanding of object oriented programming in Python, as well as the use of integrated development environments (IDE’s), Git/GitHub, Python package management systems like pip, pipenv, conda and poetry, etc.

    Legal authorization to work in the U.S. is required. Zymergen may agree to sponsor an individual for an employment visa now or in the future if there is a shortage of individuals with particular skills for this job.

    In compliance with federal law, all persons hired will be required to verify identity and eligibility to work in the United States and to complete the required employment eligibility verification form upon hire.

  • Bioengineers and Scientists

    We are hiring bioengineers and scientists to help us accelerate the next-generation of medicines using cell-free!

    Who we are:
    SwiftScale Biologics uses our cell-free protein synthesis platform to enable (1) fast protein therapeutic development through to clinical batches and (2) synthesis of proteins that are very difficult to express in cells. Our mission is to enable our partners at top biotechs to advance dozens of novel therapeutics to the clinic. We have recently raised $20M from top investors, and are founded by field-leading professors in cell-free protein synthesis, Mike Jewett and Matt DeLisa.

    What we’re looking for:
    We are looking for someone who shares our goal of getting life-saving therapeutics to patients more quickly to join our tightly-knit team in South San Francisco, CA. You’ll expand the applications of cell-free technology by interfacing with key decision makers in major biotech companies and working with our team to deliver solutions using our growing cell-free platform.

    Key qualifications:
    •Experience with DNA design, molecular cloning, protein expression, purification, and characterization in high-throughput.

    •BS (+experience), MS, or PhD in Bioengineering, Biochemistry, Biomedical Engineering, Biotechnology, Chemical Engineering, or related fields.

    •Experience with automation and in vitro transcription translation or cell-free protein synthesis methods.

    •A drive to creatively solve problems by improving experimental workflows and developing new techniques in a fast-paced small company environment.

    Contact: [email protected]

  • Summer Teaching Assistant for BioBuilder

    About BioBuilder
    BioBuilder converts biological engineering research into hands-on laboratory content and novel problem-based learning modules that can be implemented by high school students and their teachers. Established from MIT’s Dept of BE and with National Science Foundation support, BioBuilder’s accessible curriculum has made a substantial impact on secondary and post-secondary life-science education, impacting teachers and students in nearly every state and more than 30 countries.

    Program Description
    For two weeks this summer, a group of international high school students will receive instruction in synthetic biology and biodesign principles from BioBuilder faculty. They will explore computational and creative thinking to analyze and present data. Teams will incorporate engineering principles into biodesigns of their own creation. Student deliverables will include a video presentation of their final project as well as a white paper summary of their research plan.

    Responsibilities
    The TA will assist students with topics in synthetic biology, computational and visualization techniques for biodesign, and the project design process. Work will require the TA to:
    ●Review and provide feedback to participants on assignments through Canvas platform;
    ●Meet virtually with teams to guide and assist participants through project design framework;
    ●Provide feedback on presentation and white paper drafts;
    ●Collaborate with Instructors on planning and curriculum as needed

    Qualifications
    ●Graduate student or post-doc in biological engineering
    ●Background in basic stats and coding (preferably RStudio)
    ●A strong desire to teach
    ●The ideal candidate will have some familiarity with BioBuilder curriculum and labs, or iGEM

    To apply: send an email expressing your interest in this position to BioBuilder’s Director of Operations, Jessie Klapper Elliott. [email protected]. Hire must complete a W-9 to receive stipend payment

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