Security & Engineering Biology

As the tools of engineering biology develop and unlock solutions to some of the world’s toughest challenges, the potential grows for those same technologies to be used in ways that ultimately cause harm to people or planet, resulting from either intentional, nefarious use, or from the unintended consequences of well-intentioned efforts. The EBRC Security Focus Area supports activities that bring academic, government, and industry engineering biology stakeholders together to understand the nature of these potential negative outcomes and build strategies to minimize and mitigate them. By weaving engagement with security issues into the fabric of engineering biology training and research, we aim to support the field as it delivers on the promises of engineering biology without assuming unacceptable risks of negative outcomes.

Just Released:

Strengthening a Safe and Secure Nucleic Acid Synthesis Ecosystem

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Programs & Activities

  • Building International Best Practices For Robust Synthetic Nucleic Acid Screening

    This project aims to establish a set of internationally recognized best practices for nucleic acid synthesis screening through a coordinated global approach. This initiative will build on EBRC’s previous work to enhance biosecurity and ensure screening practices are robust and resilient to evolving technological risks.

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  • End-to-End Stress Testing (E2EST) of DNA Synthesis Screening

    This project will conduct end-to-end stress testing (E2EST) of nucleic acid synthesis providers. We will use customers with different attributes and sequences with different biorisk profiles to learn about provider customer, sequence, and follow-up screening practices.

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  • Enabling Quality, Measurable Synthetic DNA Sequence Screening

    This project aims to improve DNA synthesis screening by enabling the development of better tools and mechanisms for screening performance evaluation.

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  • Malice Analysis: Assessing Biotechnology Research for Security Concerns

    EBRC’s Malice Analysis program endeavors to build and support security awareness within the engineering biology community by training participants to evaluate their own work for security concerns. By providing participants with the tools and framework to engage in this type of analysis, EBRC hopes they will be prepared to consider, discuss, and improve security in engineering biology research throughout their careers.

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  • BIoSecurity Opportunities Nexus

    BIoSecurity Opportunities Nexus (BISON) compiles student and postdoc-relevant biosecurity opportunities, including graduate and postdoc academic programs, scholarships, fellowships, and internships. BISON includes both international and domestic (US) opportunities.

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Working Group

The Security Working Group is comprised of synthetic biology professionals from academia, industry, and government who keep abreast of new developments in the field and communicate the security implications of these developments to appropriate stakeholders. This group also serves as a resource for external organizations to draw upon for technical expertise from practitioners with an understanding of security implications.

Chair: Kate Adamala
Staff Director: Becky Mackelprang
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    John Glass
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    Nathan Hillson
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    Laurie Zoloth
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