Nucleic Acid Synthesis Screening elements of EO 14292: Improving the Safety and Security of Biological Research

Publication Date: June 2025

The Trump Administration released Executive Order 14292: Improving the Safety and Security of Biological Research in May 2025. The EO directed the Office of Science and Technology Policy (OSTP) to develop an updated framework for nucleic acid synthesis screening. This EBRC comment highlights reasonable strategies for screening assessments and the need for regular updates to screening standards.

Keywords: nucleic acid synthesis screening, biosecurity policy, sequences of concern

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