Calin Plesa is an Assistant Professor in the Phil and Penny Knight Campus for Accelerating Scientific Impact at the University of Oregon. He received a BASc in Engineering Physics from Simon Fraser University, a MSc in Nanoscience from Chalmers University of Technology, and a PhD from Delft University of Technology in Bionanoscience. As an HFSP Fellow in the Kosuri lab at UCLA he developed DropSynth, a low-cost scalable method to synthesize thousands of genes. Calin holds a CASI award from the Burroughs Wellcome Fund and started his lab at the University of Oregon in 2019.
The Plesa lab focuses on accelerating the pace at which we understand and engineer biological protein-based systems. Towards this end, we develop new technologies for gene synthesis, multiplex functional assays, in-vivo mutagenesis, and genotype-phenotype linkages for a number of different research areas and applications. These allow us to both access the huge sequence diversity present in natural systems as well as carry out testing of rationally designed hypotheses encoded onto DNA at much larger scales than previously possible.