[CANCELLED] Malice Analysis, North Carolina State University

The Engineering Biology Research Consortium’s Malice Analysis workshop at NCSU on April 8 is cancelled due to the COVID-19 pandemic.

We appreciate your interest. Feel free to reach out to EBRC at helix@ebrc.org if you would like more information on security in engineering biology.

Biology is easier than ever to engineer. This reality requires researchers to take proactive steps to consider the security implications of their work. The Engineering Biology Research Consortium (EBRC) is holding an interactive workshop to help you identify potentially malicious applications of your work, mitigation options, and what to do if you identify something and don’t know how to proceed. This four-hour, technically-focused workshop will include plenary presentations and discussion and small group analysis of participant projects. Refreshments will be served culminating with lunch as part of the final debrief. Participants that complete all aspects of the workshop will receive a certificate of completion which can be noted on your CV.

This workshop is supported by the U.S. Department of Homeland Security under Grant Award Number, 2017‐ST‐108‐FRG002.

[CANCELLED] Malice Analysis, Rice University

The Engineering Biology Research Consortium’s Malice Analysis workshop at Rice University on April 1, 2020 has been cancelled to the COVID-19 pandemic.

We appreciate your interest. Feel free to reach out to EBRC at helix@ebrc.org if you would like more information on security in engineering biology.

Biology is easier than ever to engineer. This reality requires researchers to take proactive steps to consider the security implications of their work. The Engineering Biology Research Consortium (EBRC) is holding an interactive workshop to help you identify potentially malicious applications of your work, mitigation options, and what to do if you identify something and don’t know how to proceed. This four-hour, technically-focused workshop will include plenary presentations and discussion and small group analysis of participant projects. Refreshments will be served culminating with lunch as part of the final debrief. Participants that complete all aspects of the workshop will receive a certificate of completion which can be noted on your CV.

This workshop is supported by the U.S. Department of Homeland Security under Grant Award Number, 2017‐ST‐108‐FRG002.

[VIRTUAL] Writing Workshop: An EBRC Roadmap for Microbiome Engineering

Participation in this workshop is by invitation only.

Registration for this workshop is now closed. Please contact roadmap@ebrc.org for more information.


As a follow-up to EBRC’s 2019 roadmap Engineering Biology, we are developing a technical research roadmap for microbiome engineering, to be published in Summer 2020. Microbiomes have the capacity to substantially influence their environment in novel ways, and therefore engineering and applying these technologies has broad implications for industry, agriculture, medicine, and other biotechnology sectors. Our primary technical themes focus on spatial and temporal microbiome engineering, stably engineering ecological diversity, and engineering cooperative biosynthesis of compounds to facilitate novel biochemistry.

This (now virtual) writing workshop will be a critical opportunity to elaborate on and refine the technical content of the roadmap, and discuss the application and impacts of engineered microbiomes. Workshop activities are expected to include:

  • Plenary discussion of existing technical themes, goals, and breakthrough capabilities;
  • Breakout groups to detail technical milestones, and accompanying Bottlenecks and Potential Solutions;
  • Breakout groups to draft and revise application sector content, with a particular focus on Health & Medicine, Energy, and Industrial Biotechnology; and
  • Plenary and breakout group review of material.

Agenda

[VIRTUAL] Writing Workshop: An EBRC Roadmap for Materials Engineering

Participation in this virtual workshop is by invitation only. Please contact roadmap@ebrc.org for more information.


As a follow-up to EBRC’s 2019 roadmap Engineering Biology, we are developing a technical research roadmap for materials from engineering biology, to be published in Summer 2020, focusing on technologies related to:

  • The structure and functionality of biological and inorganic materials,
  • Production of novel and defined biopolymers,
  • Engineering cells and consortia to produce challenging natural materials and compounds, and
  • Tools and technologies for the production of living materials that incorporate  cells to sustain active and responsive behaviors.

The roadmap will also address applying these technologies, with broad implications for industry, agriculture, medicine, and other biotechnology sectors.

This writing workshop will be a critical opportunity to create the goals, objectives, and milestones of a roadmap for materials from engineering biology, and to articulate the impact of engineering biology applied to novel materials. Workshop activities are expected to include:

  • Plenary discussions addressing scope, high-level goals and challenges, and appropriateness of milestones;
  • Breakout groups to draft and revise content specific to technical themes and/or application spaces; and
  • Plenary and breakout group review of material.

Agenda

Nima Hajinajaf

Nima Hajinajaf is currently a Ph.D. student of Chemical Engineering at Arizona State University in Prof. Varman’s Lab. He received his master’s in Chemical Engineering from the University of Tehran. His previous work was on “Photobioreactor optimization for CO2 removal and wastewater treatment by microalgae”. Currently, his work is on the Metabolic Engineering of Cyanobacteria and Bacteria to produce chemicals

Writing Workshop: An EBRC Roadmap for Microbiomes Engineering

Participation in this workshop is by invitation only. Please contact roadmap@ebrc.org for more information.

Draft Agenda


Microbiomes have the capacity to substantially influence their environment in novel ways, and therefore engineering and applying these technologies has broad implications for industry, agriculture, medicine, and other biotechnology sectors.

This writing workshop will be a critical opportunity to refine the scope, topics, and themes of a roadmap for microbiome engineering, and to create the technical content of the roadmap. Workshop activities are expected to include:

  • Plenary discussions addressing scope, high-level goals and challenges, and appropriateness of milestones;
  • Breakout groups to draft and revise content specific to technical themes and/or application spaces; and
  • Plenary and breakout group review of material.

Malice Analysis, University of Washington

Register Here

Biology is easier than ever to engineer. This reality requires researchers to take proactive steps to consider the security implications of their work. The Engineering Biology Research Consortium (EBRC) is holding an interactive workshop to help you identify potentially malicious applications of your work, mitigation options, and what to do if you identify something and don’t know how to proceed. This four-hour, technically-focused workshop will include plenary presentations and discussion and small group analysis of participant projects. Refreshments will be served culminating with lunch as part of the final debrief. Participants that complete all aspects of the workshop will receive a certificate of completion which can be noted on your CV.

This workshop is supported by the U.S. Department of Homeland Security under Grant Award Number, 2017‐ST‐108‐FRG002.

Malice Analysis, Colorado State University

Biology is easier than ever to engineer. This reality requires researchers to take proactive steps to consider the security implications of their work. The Engineering Biology Research Consortium (EBRC) is holding an interactive workshop to help you identify potentially malicious applications of your work, mitigation options, and what to do if you identify something and don’t know how to proceed. This four-hour, technically-focused workshop will include plenary presentations and discussion and small group analysis of participant projects.  Participants that complete all aspects of the workshop will receive a certificate of completion which can be noted on your CV.

Tuesday, December 8, 2020
1:00-5:00 PM Mountain Time, 12:00-4:00 PM Pacific Time

Register Here

Malice Analysis: Colorado State is being hosted by CSU faculty to better build and support a local security community in Colorado. Thus, this Malice Analysis workshop will preferentially accept participants from the Fort Collins area. However, all are welcome to register and will be admitted based on availability and registration date. Additional workshops will also be forthcoming. Contact Helix@ebrc.org, if you’re interested in hosting a virtual Malice Analysis workshop for your institution.

This workshop is supported by the U.S. Department of Homeland Security under Grant Award Number, 2017‐ST‐108‐FRG002.

Gene Olinger

Dr. Gene Olinger is the Director of the Galveston National Laboratory and a Professor in the Department of Microbiology & Immunology at the University of Texas Medical Branch (UTMB). He also serves as the Sealy Distinguished University Chair in Tropical & Emerging Virology and Co-Director of the Scholarly Concentration in Translational Research (SciTR). For over 20 years, Dr. Olinger has conducted and supervised in vitro and in vivo research in maximum biocontainment laboratories (BSL-2 to BSL-4) across government, industry, and academic institutions. His work has focused on high-consequence pathogens, global health security, and biodefense. Internationally recognized as a subject matter expert in virology, immunology, biorisk, biosecurity, and biosafety, he has played a critical role in outbreak response efforts, coordinating diagnostic, serological, and clinical assays to monitor patients during and after epidemics. Dr. Olinger has extensive experience in the development of medical countermeasures, including prophylactic treatments, vaccines, diagnostics, and therapeutics. In recent years, he has expanded his expertise to synthetic biology, AI/ML as well as innovative workforce development through mixed-reality and blended learning, science policy, and bioeconomy team-building.

Matthew Owens

Matt was an early team member of the NYC-based global education start-up, General Assembly, and helped spearhead GA’s first programs in NYC and Los Angeles. Before this, he worked as a strategy consultant with Stax, Inc. in Boston and as an analyst for a SF-based start-up, Gratio Capital. Matt has also worked with the founding teams of several science based ventures, including Agile Sciences and Innova Dynamics. He is a graduate of the Management and Technology and Integrated Product Design (MSE) programs at the University of Pennsylvania. In Philadelphia, Matt served on the board of Philly Startup Leaders and as an Engagement Manager for the cleantech practice of Wharton’s Small Business Development Center. He is an avid runner and when not at Harlem Biospace he can likely be found running through the city.

Gul Sadiq Afshan

Dr. Gul Sadiq Afshan is a talented biochemist and molecular biologist with 30 years’ teaching, research, and program development experience. She acquired her Ph. D at the University of WI, Milwaukee (UWM) and her post-doctorate at the School of Medicine and Public Health -University of WI, Madison. She envisioned, founded (2009) and governed (2009-2017) the stand-alone, and innovative undergraduate BioMolecular Engineering degree program, as a founding director, that attracts 50% female student population sustainably at the Milwaukee School of Engineering (MSOE). She is a passionate and effective teacher with extensive industry and community outreach experience. She is a recipient of over $6 million in grants from private and governmental bodies like NSF and NIH and is also a recipient of ASEE North Midwest Outstanding Educator Award, Outstanding Mentor Award, and Falk Excellent Engineering Educator Award. She also serves as an affiliate professor for the USA national PLTW program and has been a leader for bringing many university-level curricula, assessment, vision change, and mindset projects to fruition. She currently is a full professor at MSOE teaching BioMolecular Engineering.

Arren Liu

Arren Liu is a postdoctoral research fellow at Johns Hopkins University working with Dr. Jonathan Lynch on unravelling host-microbiota interactions and engineering microbiota for health applications. Arren received his B.S. in Genetics at Purdue University, where he completed an honors research thesis under the guidance of Dr. Kevin Solomon. Arren received his Ph.D. in Biological Design at Arizona State University, where he worked with Dr. David Nielsen and Dr. Arul Varman on metabolic engineering of microbes for the biomanufacturing of petrochemical alternatives from lignocellulosic biomass. Arren is the current EBRC SPA Membership chair and is also a part of the DEI committee for SIMB.

 

Michael Nestor

Dr. Michael W. Nestor is the Director of Neural Stem Cell Research The Hussman Institute for Autism and Co-Chair, Neural Stem Cell Working Group, Center for Stem Cell Biology & Regenerative Medicine at the University of Maryland, School of Medicine. Dr. Nestor received his Ph.D. in Neuroscience from The University of Maryland, School of Medicine and completed postdoctoral fellowships at the National Institutes of Health, Rutgers University as an NIH IRACDA Fellow, and at The New York Stem Cell Foundation, where he was also a Staff Scientist. Dr. Nestor is an AAAS Executive Branch Science & Technology Policy Fellow in the Office of Science and Advanced Scientific Computing Research in the Department of Energy where he is focused on the biosecurity and synthetic biology portfolios in the DOE. Michael is also a Adviser at The University of Maryland, Maryland Momentum Fund/UM Ventures-Department of Technology Transfer and the Abell Foundation. Dr. Nestor is a neurophysiologist with 15 years of experience and a focus on electrophysiology, neural stem cell biology, human genetics and project management. His laboratory works on assay development with an emphasis on cell based pre-clinical high throughput drug screens and phenotyping assays involving human iPSC-derived cortical organoids from individuals with autism.

Travel & Reimbursement Policy

The Engineering Biology Research Consortium is pleased to be able to provide financial support for travel to some events and activities.

Travelers may fall into one of three categories:
Category 1: Flight & Hotel Only
Category 2: Full Reimbursement
Category 3: No support available

Depending on the event, a traveler may fall into a different category than for a previous event. EBRC endeavors to provide clear guidance as to which category is in place for a particular traveler and event.

General
It is the policy of the Engineering Biology Research Consortium to support the (invited) traveler for reasonable and necessary expenses incurred during EBRC-related travel. Funded Travelers should incur the lowest reasonable travel expenses and exercise care to avoid impropriety or the appearance of impropriety. Support is allowed only when travel funding or reimbursement has not been, and will not be, received from other sources. Documentation is required for all reimbursement requests; receipts must be submitted within 30 days of the event (further details below).

  • Category 1 – Flight & Hotel Only: EBRC will provide instructions to book flights and hotel for an event. Both will be paid directly by EBRC and the traveler will not be provided reimbursement after the event. Exceptions may be made on a case-by-case basis in advance of the event.
  • Category 2 – Full Reimbursement: EBRC will provide instructions to book flights and hotel, to be paid directly by EBRC. Following the event, documentation for reimbursements must be submitted within 30 days of the last day of travel. Only actual expenses with receipt documentation can be reimbursed. EBRC does not provide a flat per diem.
  • Category 3 – No support available: Travelers are responsible for booking* and paying for most travel and accommodations. EBRC will not provide reimbursement. If a traveler would experience hardship and be unable to attend the event without support, they may contact us at helix@ebrc.org to discuss options. *For many events, EBRC will have a block of hotel rooms reserved. If given the option, Category 3 travelers may indicate they would like to be included in EBRC’s room block. Category 3 travelers must provide payment at check-in.

Transportation
Transportation expenses for Category 1 and Category 2 travelers will generally be supported based on the most economical and commonly used mode of conveyance taking the most direct route during the authorized travel dates (the days of the meeting and, in most circumstances, one day before and/or after the meeting). If you need to make an additional stop(s) en route to the meeting or after the meeting, or travel outside the travel dates, please contact us at helix@ebrc.org in advance of booking.

Airfare Guidelines
EBRC will provide flight limits for travelers covered under Category 1 and Category 2. Payment will be made directly by the EBRC to the airline. We cannot guarantee full reimbursement for air travel made outside of EBRC. If you are not able to book through EBRC, please contact us at helix@ebrc.org.

  • Only coach/economy class tickets at the lowest reasonable fare and non-refundable tickets are reimbursable. First class, business class, full-fare economy class, and unrestricted/refundable tickets are not reimbursable without advance written approval. All travel should be planned and booked as far in advance as possible to take advantage of the least-expensive fares available. Ancillary fees charged by airlines (i.e., seat selection, excess baggage) are not reimbursable.
  • If the approved process is not used and EBRC has not directly paid the airfare, comparative costs upon which airfare reimbursement can be based must be obtained. This means you will be reimbursed for the cost of a direct round-trip between your place of work and the EBRC event meeting place or the face value of the ticket, whichever is less. If the constructive cost is not determined in advance, EBRC will reference the lowest reasonable fare after the fact, and this may lower your reimbursement. If you expect to be reimbursed by a third party for any part of your travel, costs should be allocated appropriately.
  • The EBRC cannot pay airline change fees after reservations have been ticketed. Except for emergencies, the traveler will be responsible for change fees should changes arise after flights have been confirmed by the traveler and booked by the EBRC.
  • If you are unable to honor a flight reservation, you are responsible for canceling your reservation and notifying EBRC at helix@ebrc.org before the departure. Cancellations arising from non-emergency situations may require reimbursement of EBRC’s costs or restrictions on future travel with EBRC.
  • EBRC is unable to fully cover the airfare costs of international members. International members who would fall into Categories 1 or 2 should communicate their intention to travel to EBRC staff and book their own travel. After the event, such members can be reimbursed up to the highest fare limit designated for that event.

Ground Transportation

  • If driving your personal vehicle, Category 1 and Category 2 travelers may be reimbursed 65.5 cents per mile, based on the most direct route. To determine the number of miles, use an online mapping tool (MapQuest or Google Maps) and submit this documentation to us. The standard mileage rate includes fuel, as well as wear-and-tear on the vehicle. You will be reimbursed the lesser mileage based on the most direct route or an amount equal to the cost of flying coach/economy with advance booking.
  • Rental cars are generally not necessary for EBRC events and will only be supported with explicit notice in advance of an event. If a rental car is allowed, you can rent up to an intermediate-size car.
  • When traveling by train or Amtrak, you must use coach-class accommodations. EBRC can book your ticket prior to the event. Please contact us at helix@ebrc.org to make your reservation.

Lodging
Travelers in Categories 1, 2, and 3 will be invited and encouraged to stay in hotel blocks booked by EBRC. EBRC will pay directly for these accommodations for Category 1 and Category 2 travelers. Category 3 travelers must provide payment at check-in. Room incidentals are not reimbursable and are the responsibility of the traveler (all travelers will be asked to provide a credit card at check-in for incidentals, per a hotel’s policy).

Meals & Incidental Expenses (Category 2 Travelers)
If a trip is less than 24 hours, meals are not reimbursable, unless there is a need for an overnight stay. Most EBRC meetings include catered meals during the meeting; the meeting agenda will indicate when meals are provided. No reimbursement will be allowed when catered meals are provided. When meals are not provided, EBRC will reimburse a traveler’s meals, with receipts, up to the U.S. General Services Administration’s limits. EBRC cannot reimburse for alcohol purchases. If purchased alcohol is included in the submitted receipt documentation, it is the responsibility of the traveler to indicate the expense and deduct the amount from the total request.

Reporting Travel Expenses for Reimbursement (Category 2 Travelers; Category 1 Travelers upon request)
Save your receipts. Business-related expenses can be claimed for actual amounts spent, with submission of itemized receipts for all transportation and meals. A valid receipt contains payee’s name, amount, date, place, identification of what was purchased and proof of payment. EBRC cannot reimburse for alcohol purchases. If purchased alcohol is included in the submitted receipt documentation, it is the responsibility of the traveler to indicate the expense and deduct the amount from the total request. If you have lost a business receipt and have exhausted all efforts to obtain a copy from the merchant, provide an explanation with your reimbursement request including the details of the purchase and your declaration that the amount claimed is the amount actually paid by you and that you have not and will not seek reimbursement from any other source.

Exceptions
Requests for exceptions to this policy should be made as soon as possible. To request an exception, please contact us at helix@ebrc.org. This includes questions or deviations for complex travel situations.

Health and Safety
Vaccination against COVID-19, influenza, and other infectious diseases is highly recommended for in-person event participation. EBRC will employ masking and social distancing requirements per CDC and state and local guidelines to ensure the safety, health, and comfort of our participants.

Matthew Amrofell

Matt is a synthetic biology graduate student researcher at Washington University in St. Louis in the lab of Tae Seok Moon. He engineers probiotic organisms in order to develop the next generation of safe and effective living medicines. Prior to starting graduate school, he worked in Michael Jewett’s lab at Nortwestern studying post-tranlational modifications in cell-free protein synthesis reactions. He also worked several co-op terms at Baxter Healthcare. In his (limited) spare time, Matt likes to bake (and eat!) bread, play soccer, read sci-fi/fantasy, and play with his two dogs, Loki and Baloo.

Kok Zhi Lee

Kok Zhi is a postdoctoral fellow in Fuzhong Zhang’s lab at Washington University in St. Louis. He repurposes/engineers proteins in nature for biotechnology applications, tackling material synthesis and sustainability challenges. He completed his Ph.D. in Bioengineering under Kevin Solomon at Purdue University, where he characterized prokaryotic argonautes for novel gene-editing tool development without sequence-motif restrictions. Outside of research, Kok Zhi serves as a Social Chair in EBRC SPA, dedicated to creating diverse and inclusive environments for networking and career developments in the synthetic biology community.

Merja Penttilä

Merja Penttilä is a research professor in biotechnology at VTT Technical Research Centre of Finland, and an adjunct professor in synthetic biology at Aalto University. Her expertise is on engineering of microbes for the production of fuels, chemicals, enzymes and materials. She has acted as the director of the Academy of Finland CoE on White biotechnology – Green chemistry, and is a PI in the current CoE on Molecular engineering of biosynthetic hybrid materials (Hyber). She has coordinated a large strategic project “Living Factories: Synthetic Biology for a sustainable Bioeconomy”, and led many EU level and industrial projects. She is acting an advisory board or committee member of a number of international organisations. She is the initiator of Synbio Powerhouse, an ecosystem to promote biotechnology and synthetic biology in Finland and beyond. She has total of 334 publications, 14 457 Web of science citations, and h-index of 70.

Synthetic Biology In Space

This video describes how synthetic biology might enable humans to live on another planet for generations, and highlights some of the capabilities we already have and how they could be used to engineer plants – and perhaps even people – to survive and thrive in a new environment. The presenter, Lisa Nip, also touches on the ethical and moral decisions that accompany the required biological engineering feats. While the aerospace engineers are working on getting us to Mars, everyone should take part in the conversation about what we can do when we get there, and this is a great video to start that conversation.

Video from TEDx Talks.

What is a Gene Drive?

“Gene drives” are a hot topic in biotechnology, with many potential applications and ramifications. Gene drives could be used to control disease transmission, perhaps even eradicating certain diseases. There are a host of ethical issues to consider regarding gene drives too, from ecological impacts to nefarious uses by parties with bad intentions. But in order to understand all of this, it is important to have at least an initial, basic understanding of what a “gene drive” is. This video provides a quick, visually-illustrated, easy-to-understand explanation of a gene drive that will let you understand the ongoing conversations about gene drives and also think critically about their future impacts.

EauD’coli

The 2006 MIT iGEM team makes normally stinky smelling bacteria smell like bananas and mint, and openly discuss their design process in a charming presentation of really special work. The control of scent by growth phase increased the tools and the imagination for cellular inputs and outputs.