Dr. Yasuo Yoshikuni is a staff scientist at Lawrence Berkeley National Lab. He leads the DNA synthesis science user program at the DOE Joint Genome Institute (JGI). His program has already supported more than 200 user projects globally, and several major publications were published through the program. Dr. Yoshikuni’s personal research focus is to study and understand microbe- and plant-microbe communications for sustainable agriculture, developing non-model yeast for fuel and chemical production, and biomaterials synthesis using systems and synthetic biology. Before joining the DOE JGI, Dr. Yoshikuni was co-founder and chief science officer at a clean technology start-up, Bio Architecture Lab, Inc. (BAL), where his significant achievement was using systems and synthetic biology to discover novel pathways assimilating unique sugar polymers in macroalgae and to develop the first microbial platform technologies unlocking the potential of macroalgae as an environmentally sustainable and cost-effective biomass for production of renewable fuels and chemicals. The development of this technology allowed the company to build a strong IP propositions and to raise ~$40 million from private funding sources, receive prestigious national grants, and build a commercial partnership with leading companies in the oil and chemical industries. The work also led to several patents and high-impact scientific publications.